IDEAS home Printed from https://ideas.repec.org/a/nat/nature/v417y2002i6890d10.1038_nature00807.html
   My bibliography  Save this article

Role of experience and oscillations in transforming a rate code into a temporal code

Author

Listed:
  • M. R. Mehta

    (Massachusetts Institute of Technology
    Massachusetts Institute of Technology)

  • A. K. Lee

    (Massachusetts Institute of Technology
    Massachusetts Institute of Technology)

  • M. A. Wilson

    (Massachusetts Institute of Technology
    Massachusetts Institute of Technology)

Abstract

In the vast majority of brain areas, the firing rates of neurons, averaged over several hundred milliseconds to several seconds, can be strongly modulated by, and provide accurate information about, properties of their inputs. This is referred to as the rate code. However, the biophysical laws of synaptic plasticity require precise timing of spikes over short timescales (

Suggested Citation

  • M. R. Mehta & A. K. Lee & M. A. Wilson, 2002. "Role of experience and oscillations in transforming a rate code into a temporal code," Nature, Nature, vol. 417(6890), pages 741-746, June.
    • Handle: RePEc:nat:nature:v:417:y:2002:i:6890:d:10.1038_nature00807
    DOI: 10.1038/nature00807
    as

    Download full text from publisher

    File URL: https://www.nature.com/articles/nature00807
    File Function: Abstract
    Download Restriction: Access to the full text of the articles in this series is restricted.
    File URL: https://libkey.io/10.1038/nature00807?utm_source=ideas
    LibKey link: if access is restricted and if your library uses this service, LibKey will redirect you to where you can use your library subscription to access this item
    ---><---

    As the access to this document is restricted, you may want to search for a different version of it.

    Citations

    Citations are extracted by the CitEc Project, subscribe to its RSS feed for this item.
    as


    Cited by:

    1. Zhenrui Liao & Kevin C. Gonzalez & Deborah M. Li & Catalina M. Yang & Donald Holder & Natalie E. McClain & Guofeng Zhang & Stephen W. Evans & Mariya Chavarha & Jane Simko & Christopher D. Makinson & M, 2024. "Functional architecture of intracellular oscillations in hippocampal dendrites," Nature Communications, Nature, vol. 15(1), pages 1-16, December.
    2. Matthieu Gilson & Tomoki Fukai, 2011. "Stability versus Neuronal Specialization for STDP: Long-Tail Weight Distributions Solve the Dilemma," PLOS ONE, Public Library of Science, vol. 6(10), pages 1-18, October.
    3. Eric Reifenstein & Martin Stemmler & Andreas V M Herz & Richard Kempter & Susanne Schreiber, 2014. "Movement Dependence and Layer Specificity of Entorhinal Phase Precession in Two-Dimensional Environments," PLOS ONE, Public Library of Science, vol. 9(6), pages 1-11, June.
    4. Krishna Choudhary & Sven Berberich & Thomas T. G. Hahn & James M. McFarland & Mayank R. Mehta, 2024. "Spontaneous persistent activity and inactivity in vivo reveals differential cortico-entorhinal functional connectivity," Nature Communications, Nature, vol. 15(1), pages 1-15, December.
    5. Louis Kang & Taro Toyoizumi, 2024. "Distinguishing examples while building concepts in hippocampal and artificial networks," Nature Communications, Nature, vol. 15(1), pages 1-19, December.
    6. Eleonora Russo & Nadine Becker & Aleks P. F. Domanski & Timothy Howe & Kipp Freud & Daniel Durstewitz & Matthew W. Jones, 2024. "Integration of rate and phase codes by hippocampal cell-assemblies supports flexible encoding of spatiotemporal context," Nature Communications, Nature, vol. 15(1), pages 1-17, December.
    7. Gosak, Marko & Markovič, Rene & Marhl, Marko, 2012. "The role of neural architecture and the speed of signal propagation in the process of synchronization of bursting neurons," Physica A: Statistical Mechanics and its Applications, Elsevier, vol. 391(8), pages 2764-2770.
    8. Matthieu Gilson & Tomoki Fukai & Anthony N Burkitt, 2012. "Spectral Analysis of Input Spike Trains by Spike-Timing-Dependent Plasticity," PLOS Computational Biology, Public Library of Science, vol. 8(7), pages 1-22, July.
    9. Dhanya Parameshwaran & Upinder S Bhalla, 2013. "Theta Frequency Background Tunes Transmission but Not Summation of Spiking Responses," PLOS ONE, Public Library of Science, vol. 8(1), pages 1-12, January.
    10. Sara Mahallati & James C Bezdek & Milos R Popovic & Taufik A Valiante, 2019. "Cluster tendency assessment in neuronal spike data," PLOS ONE, Public Library of Science, vol. 14(11), pages 1-29, November.

    More about this item

    Statistics

    Access and download statistics

    Corrections

    All material on this site has been provided by the respective publishers and authors. You can help correct errors and omissions. When requesting a correction, please mention this item's handle: RePEc:nat:nature:v:417:y:2002:i:6890:d:10.1038_nature00807. See general information about how to correct material in RePEc.

    If you have authored this item and are not yet registered with RePEc, we encourage you to do it here. This allows to link your profile to this item. It also allows you to accept potential citations to this item that we are uncertain about.

    We have no bibliographic references for this item. You can help adding them by using this form .

    If you know of missing items citing this one, you can help us creating those links by adding the relevant references in the same way as above, for each refering item. If you are a registered author of this item, you may also want to check the "citations" tab in your RePEc Author Service profile, as there may be some citations waiting for confirmation.

    For technical questions regarding this item, or to correct its authors, title, abstract, bibliographic or download information, contact: Sonal Shukla or Springer Nature Abstracting and Indexing (email available below). General contact details of provider: http://www.nature.com .

    Please note that corrections may take a couple of weeks to filter through the various RePEc services.

    IDEAS is a RePEc service. RePEc uses bibliographic data supplied by the respective publishers.