IDEAS home Printed from https://ideas.repec.org/a/nat/nature/v415y2002i6868d10.1038_415219a.html
   My bibliography  Save this article

New ideas about atrial fibrillation 50 years on

Author

Listed:
  • Stanley Nattel

    (Montreal Heart Institute Research Center, Montreal Heart Institute and University of Montreal)

Abstract

Atrial fibrillation is a condition in which control of heart rhythm is taken away from the normal sinus node pacemaker by rapid activity in different areas within the upper chambers (atria) of the heart. This results in rapid and irregular atrial activity and, instead of contracting, the atria only quiver. It is the most common cardiac rhythm disturbance and contributes substantially to cardiac morbidity and mortality. For over 50 years, the prevailing model of atrial fibrillation involved multiple simultaneous re-entrant waves, but in light of new discoveries this hypothesis is now undergoing re-evaluation.

Suggested Citation

  • Stanley Nattel, 2002. "New ideas about atrial fibrillation 50 years on," Nature, Nature, vol. 415(6868), pages 219-226, January.
    • Handle: RePEc:nat:nature:v:415:y:2002:i:6868:d:10.1038_415219a
    DOI: 10.1038/415219a
    as

    Download full text from publisher

    File URL: https://www.nature.com/articles/415219a
    File Function: Abstract
    Download Restriction: Access to the full text of the articles in this series is restricted.
    File URL: https://libkey.io/10.1038/415219a?utm_source=ideas
    LibKey link: if access is restricted and if your library uses this service, LibKey will redirect you to where you can use your library subscription to access this item
    ---><---

    As the access to this document is restricted, you may want to search for a different version of it.

    Citations

    Citations are extracted by the CitEc Project, subscribe to its RSS feed for this item.
    as


    Cited by:

    1. Feng Ou & Nini Rao & Xudong Jiang & Mengyao Qian & Wei Feng & Lixue Yin & Xu Chen, 2013. "Analysis on Differential Gene Expression Data for Prediction of New Biological Features in Permanent Atrial Fibrillation," PLOS ONE, Public Library of Science, vol. 8(10), pages 1-8, October.
    2. Eberhard P Scholz & Paola Carrillo-Bustamante & Fathima Fischer & Mathias Wilhelms & Edgar Zitron & Olaf Dössel & Hugo A Katus & Gunnar Seemann, 2013. "Rotor Termination Is Critically Dependent on Kinetic Properties of IKur Inhibitors in an In Silico Model of Chronic Atrial Fibrillation," PLOS ONE, Public Library of Science, vol. 8(12), pages 1-11, December.
    3. Michael A Colman, 2019. "Arrhythmia mechanisms and spontaneous calcium release: Bi-directional coupling between re-entrant and focal excitation," PLOS Computational Biology, Public Library of Science, vol. 15(8), pages 1-34, August.
    4. Daniel M Lombardo & Flavio H Fenton & Sanjiv M Narayan & Wouter-Jan Rappel, 2016. "Comparison of Detailed and Simplified Models of Human Atrial Myocytes to Recapitulate Patient Specific Properties," PLOS Computational Biology, Public Library of Science, vol. 12(8), pages 1-15, August.
    5. Yan-yan Li & Chuan-wei Zhou & Jian Xu & Yun Qian & Bei Wang, 2012. "CYP11B2 T-344C Gene Polymorphism and Atrial Fibrillation: A Meta-Analysis of 2,758 Subjects," PLOS ONE, Public Library of Science, vol. 7(11), pages 1-7, November.
    6. Cui, Xingran & Chang, Hung-Chi & Lin, Lian-Yu & Yu, Chih-Chieh & Hsieh, Wan-Hsin & Li, Weihui & Peng, Chung-Kang & Lin, Jiunn-Lee & Lo, Men-Tzung, 2019. "Prediction of atrial fibrillation recurrence before catheter ablation using an adaptive nonlinear and non-stationary surface ECG analysis," Physica A: Statistical Mechanics and its Applications, Elsevier, vol. 514(C), pages 9-19.
    7. Narin, Ali & Isler, Yalcin & Ozer, Mahmut & Perc, Matjaž, 2018. "Early prediction of paroxysmal atrial fibrillation based on short-term heart rate variability," Physica A: Statistical Mechanics and its Applications, Elsevier, vol. 509(C), pages 56-65.

    More about this item

    Statistics

    Access and download statistics

    Corrections

    All material on this site has been provided by the respective publishers and authors. You can help correct errors and omissions. When requesting a correction, please mention this item's handle: RePEc:nat:nature:v:415:y:2002:i:6868:d:10.1038_415219a. See general information about how to correct material in RePEc.

    If you have authored this item and are not yet registered with RePEc, we encourage you to do it here. This allows to link your profile to this item. It also allows you to accept potential citations to this item that we are uncertain about.

    We have no bibliographic references for this item. You can help adding them by using this form .

    If you know of missing items citing this one, you can help us creating those links by adding the relevant references in the same way as above, for each refering item. If you are a registered author of this item, you may also want to check the "citations" tab in your RePEc Author Service profile, as there may be some citations waiting for confirmation.

    For technical questions regarding this item, or to correct its authors, title, abstract, bibliographic or download information, contact: Sonal Shukla or Springer Nature Abstracting and Indexing (email available below). General contact details of provider: http://www.nature.com .

    Please note that corrections may take a couple of weeks to filter through the various RePEc services.

    IDEAS is a RePEc service. RePEc uses bibliographic data supplied by the respective publishers.