NPC1 controls TGFBR1 stability in a cholesterol transport-independent manner and promotes hepatocellular carcinoma progression
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DOI: 10.1038/s41467-024-55788-5
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- Ting-Ting Chu & Xintao Tu & Kun Yang & Jianjun Wu & Joyce J. Repa & Nan Yan, 2021. "Tonic prime-boost of STING signalling mediates Niemann–Pick disease type C," Nature, Nature, vol. 596(7873), pages 570-575, August.
- Jan E. Carette & Matthijs Raaben & Anthony C. Wong & Andrew S. Herbert & Gregor Obernosterer & Nirupama Mulherkar & Ana I. Kuehne & Philip J. Kranzusch & April M. Griffin & Gordon Ruthel & Paola Dal C, 2011. "Ebola virus entry requires the cholesterol transporter Niemann–Pick C1," Nature, Nature, vol. 477(7364), pages 340-343, September.
- Marceline Côté & John Misasi & Tao Ren & Anna Bruchez & Kyungae Lee & Claire Marie Filone & Lisa Hensley & Qi Li & Daniel Ory & Kartik Chandran & James Cunningham, 2011. "Small molecule inhibitors reveal Niemann–Pick C1 is essential for Ebola virus infection," Nature, Nature, vol. 477(7364), pages 344-348, September.
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