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An African perspective on genetically diverse human induced pluripotent stem cell lines

Author

Listed:
  • Tracey Hurrell

    (Council for Scientific and Industrial Research)

  • Jerolen Naidoo

    (Council for Scientific and Industrial Research
    University of Cape Town)

  • Tiro Ntlhafu

    (Council for Scientific and Industrial Research)

  • Janine Scholefield

    (Council for Scientific and Industrial Research
    University of Cape Town
    University of the Witwatersrand)

Abstract

Human induced pluripotent stem cell-derived models are a well-established preclinical tool, with the ability to retain the genetics of the individual from which they are derived. Here we comment on the global representation and accessibility of such cellular tools from African population groups.

Suggested Citation

  • Tracey Hurrell & Jerolen Naidoo & Tiro Ntlhafu & Janine Scholefield, 2024. "An African perspective on genetically diverse human induced pluripotent stem cell lines," Nature Communications, Nature, vol. 15(1), pages 1-5, December.
    • Handle: RePEc:nat:natcom:v:15:y:2024:i:1:d:10.1038_s41467-024-52781-w
    DOI: 10.1038/s41467-024-52781-w
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    References listed on IDEAS

    as
    1. Sulagna Ghosh & Ralda Nehme & Lindy E. Barrett, 2022. "Greater genetic diversity is needed in human pluripotent stem cell models," Nature Communications, Nature, vol. 13(1), pages 1-7, December.
    2. Ananyo Choudhury & Shaun Aron & Laura R. Botigué & Dhriti Sengupta & Gerrit Botha & Taoufik Bensellak & Gordon Wells & Judit Kumuthini & Daniel Shriner & Yasmina J. Fakim & Anisah W. Ghoorah & Eileen , 2020. "High-depth African genomes inform human migration and health," Nature, Nature, vol. 586(7831), pages 741-748, October.
    3. Cesar A. Fortes-Lima & Concetta Burgarella & Rickard Hammarén & Anders Eriksson & Mário Vicente & Cecile Jolly & Armando Semo & Hilde Gunnink & Sara Pacchiarotti & Leon Mundeke & Igor Matonda & Joseph, 2024. "The genetic legacy of the expansion of Bantu-speaking peoples in Africa," Nature, Nature, vol. 625(7995), pages 540-547, January.
    Full references (including those not matched with items on IDEAS)

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