The transcription factor ChREBP Orchestrates liver carcinogenesis by coordinating the PI3K/AKT signaling and cancer metabolism
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DOI: 10.1038/s41467-024-45548-w
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- Dannielle DeWaal & Veronique Nogueira & Alexander R. Terry & Krushna C. Patra & Sang-Min Jeon & Grace Guzman & Jennifer Au & Christopher P. Long & Maciek R. Antoniewicz & Nissim Hay, 2018. "Author Correction: Hexokinase-2 depletion inhibits glycolysis and induces oxidative phosphorylation in hepatocellular carcinoma and sensitizes to metformin," Nature Communications, Nature, vol. 9(1), pages 1-1, December.
- Quentin Bayard & Léa Meunier & Camille Peneau & Victor Renault & Jayendra Shinde & Jean-Charles Nault & Iadh Mami & Gabrielle Couchy & Giuliana Amaddeo & Emmanuel Tubacher & Delphine Bacq & Vincent Me, 2018. "Cyclin A2/E1 activation defines a hepatocellular carcinoma subclass with a rearrangement signature of replication stress," Nature Communications, Nature, vol. 9(1), pages 1-14, December.
- Richard Possemato & Kevin M. Marks & Yoav D. Shaul & Michael E. Pacold & Dohoon Kim & Kıvanç Birsoy & Shalini Sethumadhavan & Hin-Koon Woo & Hyun G. Jang & Abhishek K. Jha & Walter W. Chen & Francesca, 2011. "Functional genomics reveal that the serine synthesis pathway is essential in breast cancer," Nature, Nature, vol. 476(7360), pages 346-350, August.
- Ji Hoon Kim & Bo Hwa Sohn & Hyun-Sung Lee & Sang-Bae Kim & Jeong Eun Yoo & Yun-Yong Park & Woojin Jeong & Sung Sook Lee & Eun Sung Park & Ahmed Kaseb & Baek Hui Kim & Wan Bae Kim & Jong Eun Yeon & Kwa, 2014. "Genomic Predictors for Recurrence Patterns of Hepatocellular Carcinoma: Model Derivation and Validation," PLOS Medicine, Public Library of Science, vol. 11(12), pages 1-16, December.
- Dannielle DeWaal & Veronique Nogueira & Alexander R. Terry & Krushna C. Patra & Sang-Min Jeon & Grace Guzman & Jennifer Au & Christopher P. Long & Maciek R. Antoniewicz & Nissim Hay, 2018. "Hexokinase-2 depletion inhibits glycolysis and induces oxidative phosphorylation in hepatocellular carcinoma and sensitizes to metformin," Nature Communications, Nature, vol. 9(1), pages 1-14, December.
- Eline Sijbesma & Emira Visser & Kathrin Plitzko & Philipp Thiel & Lech-Gustav Milroy & Markus Kaiser & Luc Brunsveld & Christian Ottmann, 2020. "Structure-based evolution of a promiscuous inhibitor to a selective stabilizer of protein–protein interactions," Nature Communications, Nature, vol. 11(1), pages 1-9, December.
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