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Magnaporthe oryzae effector MoSPAB1 directly activates rice Bsr-d1 expression to facilitate pathogenesis

Author

Listed:
  • Ziwei Zhu

    (Sichuan Agricultural University
    Chengdu University)

  • Jun Xiong

    (Sichuan Agricultural University)

  • Hao Shi

    (Sichuan Agricultural University)

  • Yuchen Liu

    (Sichuan Agricultural University)

  • Junjie Yin

    (Sichuan Agricultural University)

  • Kaiwei He

    (Sichuan Agricultural University)

  • Tianyu Zhou

    (Sichuan Agricultural University)

  • Liting Xu

    (Sichuan Agricultural University)

  • Xiaobo Zhu

    (Sichuan Agricultural University)

  • Xiang Lu

    (Sichuan Agricultural University)

  • Yongyan Tang

    (Sichuan Agricultural University)

  • Li Song

    (Sichuan Agricultural University)

  • Qingqing Hou

    (Sichuan Agricultural University)

  • Qing Xiong

    (Sichuan Agricultural University)

  • Long Wang

    (Sichuan Agricultural University)

  • Daihua Ye

    (Sichuan Agricultural University)

  • Tuo Qi

    (Mianyang Teachers’ College)

  • Lijuan Zou

    (Mianyang Teachers’ College)

  • Guobang Li

    (Sichuan Agricultural University)

  • Changhui Sun

    (Sichuan Agricultural University)

  • Zhiyue Wu

    (Sichuan Agricultural University)

  • Peili Li

    (Sichuan Agricultural University)

  • Jiali Liu

    (Sichuan Agricultural University)

  • Yu Bi

    (Sichuan Agricultural University)

  • Yihua Yang

    (Sichuan Agricultural University)

  • Chunxian Jiang

    (Sichuan Agricultural University)

  • Jing Fan

    (Sichuan Agricultural University)

  • Guoshu Gong

    (Sichuan Agricultural University)

  • Min He

    (Sichuan Agricultural University)

  • Jing Wang

    (Sichuan Agricultural University)

  • Xuewei Chen

    (Sichuan Agricultural University)

  • Weitao Li

    (Sichuan Agricultural University)

Abstract

Fungal pathogens typically use secreted effector proteins to suppress host immune activators to facilitate invasion. However, there is rarely evidence supporting the idea that fungal secretory proteins contribute to pathogenesis by transactivating host genes that suppress defense. We previously found that pathogen Magnaporthe oryzae induces rice Bsr-d1 to facilitate infection and hypothesized that a fungal effector mediates this induction. Here, we report that MoSPAB1 secreted by M. oryzae directly binds to the Bsr-d1 promoter to induce its expression, facilitating pathogenesis. Amino acids 103-123 of MoSPAB1 are required for its binding to the Bsr-d1 promoter. Both MoSPAB1 and rice MYBS1 compete for binding to the Bsr-d1 promoter to regulate Bsr-d1 expression. Furthermore, MoSPAB1 homologues are highly conserved among fungi. In particular, Colletotrichum fructicola CfSPAB1 and Colletotrichum sublineola CsSPAB1 activate kiwifruit AcBsr-d1 and sorghum SbBsr-d1 respectively, to facilitate pathogenesis. Taken together, our findings reveal a conserved module that may be widely utilized by fungi to enhance pathogenesis.

Suggested Citation

  • Ziwei Zhu & Jun Xiong & Hao Shi & Yuchen Liu & Junjie Yin & Kaiwei He & Tianyu Zhou & Liting Xu & Xiaobo Zhu & Xiang Lu & Yongyan Tang & Li Song & Qingqing Hou & Qing Xiong & Long Wang & Daihua Ye & T, 2023. "Magnaporthe oryzae effector MoSPAB1 directly activates rice Bsr-d1 expression to facilitate pathogenesis," Nature Communications, Nature, vol. 14(1), pages 1-12, December.
  • Handle: RePEc:nat:natcom:v:14:y:2023:i:1:d:10.1038_s41467-023-44197-9
    DOI: 10.1038/s41467-023-44197-9
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    References listed on IDEAS

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