IDEAS home Printed from https://ideas.repec.org/a/nat/natcom/v14y2023i1d10.1038_s41467-023-41903-5.html
   My bibliography  Save this article

In situ electron paramagnetic resonance spectroscopy using single nanodiamond sensors

Author

Listed:
  • Zhuoyang Qin

    (University of Science and Technology of China
    University of Science and Technology of China)

  • Zhecheng Wang

    (University of Science and Technology of China
    University of Science and Technology of China)

  • Fei Kong

    (University of Science and Technology of China
    University of Science and Technology of China
    University of Science and Technology of China)

  • Jia Su

    (University of Science and Technology of China
    University of Science and Technology of China)

  • Zhehua Huang

    (University of Science and Technology of China
    University of Science and Technology of China)

  • Pengju Zhao

    (University of Science and Technology of China
    University of Science and Technology of China)

  • Sanyou Chen

    (University of Science and Technology of China
    University of Science and Technology of China
    University of Science and Technology of China)

  • Qi Zhang

    (University of Science and Technology of China
    University of Science and Technology of China
    University of Science and Technology of China)

  • Fazhan Shi

    (University of Science and Technology of China
    University of Science and Technology of China
    University of Science and Technology of China
    University of Science and Technology of China)

  • Jiangfeng Du

    (University of Science and Technology of China
    University of Science and Technology of China
    University of Science and Technology of China
    Zhejiang University)

Abstract

An ultimate goal of electron paramagnetic resonance (EPR) spectroscopy is to analyze molecular dynamics in place where it occurs, such as in a living cell. The nanodiamond (ND) hosting nitrogen-vacancy (NV) centers will be a promising EPR sensor to achieve this goal. However, ND-based EPR spectroscopy remains elusive, due to the challenge of controlling NV centers without well-defined orientations inside a flexible ND. Here, we show a generalized zero-field EPR technique with spectra robust to the sensor’s orientation. The key is applying an amplitude modulation on the control field, which generates a series of equidistant Floquet states with energy splitting being the orientation-independent modulation frequency. We acquire the zero-field EPR spectrum of vanadyl ions in aqueous glycerol solution with embedded single NDs, paving the way towards in vivo EPR.

Suggested Citation

  • Zhuoyang Qin & Zhecheng Wang & Fei Kong & Jia Su & Zhehua Huang & Pengju Zhao & Sanyou Chen & Qi Zhang & Fazhan Shi & Jiangfeng Du, 2023. "In situ electron paramagnetic resonance spectroscopy using single nanodiamond sensors," Nature Communications, Nature, vol. 14(1), pages 1-8, December.
    • Handle: RePEc:nat:natcom:v:14:y:2023:i:1:d:10.1038_s41467-023-41903-5
    DOI: 10.1038/s41467-023-41903-5
    as

    Download full text from publisher

    File URL: https://www.nature.com/articles/s41467-023-41903-5
    File Function: Abstract
    Download Restriction: no
    File URL: https://libkey.io/10.1038/s41467-023-41903-5?utm_source=ideas
    LibKey link: if access is restricted and if your library uses this service, LibKey will redirect you to where you can use your library subscription to access this item
    ---><---

    References listed on IDEAS

    as
    1. L. T. Hall & P. Kehayias & D. A. Simpson & A. Jarmola & A. Stacey & D. Budker & L. C. L. Hollenberg, 2016. "Detection of nanoscale electron spin resonance spectra demonstrated using nitrogen-vacancy centre probes in diamond," Nature Communications, Nature, vol. 7(1), pages 1-9, April.
    2. David A. Simpson & Robert G. Ryan & Liam T. Hall & Evgeniy Panchenko & Simon C. Drew & Steven Petrou & Paul S. Donnelly & Paul Mulvaney & Lloyd C. L. Hollenberg, 2017. "Electron paramagnetic resonance microscopy using spins in diamond under ambient conditions," Nature Communications, Nature, vol. 8(1), pages 1-8, December.
    3. Dinesh Pinto & Domenico Paone & Bastian Kern & Tim Dierker & René Wieczorek & Aparajita Singha & Durga Dasari & Amit Finkler & Wolfgang Harneit & Jörg Wrachtrup & Klaus Kern, 2020. "Readout and control of an endofullerene electronic spin," Nature Communications, Nature, vol. 11(1), pages 1-6, December.
    4. S. Steinert & F. Ziem & L. T. Hall & A. Zappe & M. Schweikert & N. Götz & A. Aird & G. Balasubramanian & L. Hollenberg & J. Wrachtrup, 2013. "Magnetic spin imaging under ambient conditions with sub-cellular resolution," Nature Communications, Nature, vol. 4(1), pages 1-6, June.
    5. T. Staudacher & N. Raatz & S. Pezzagna & J. Meijer & F. Reinhard & C. A. Meriles & J. Wrachtrup, 2015. "Probing molecular dynamics at the nanoscale via an individual paramagnetic centre," Nature Communications, Nature, vol. 6(1), pages 1-7, December.
    6. Shangguo Hou & Jack Exell & Kevin Welsher, 2020. "Real-time 3D single molecule tracking," Nature Communications, Nature, vol. 11(1), pages 1-10, December.
    7. Dominik M. Irber & Francesco Poggiali & Fei Kong & Michael Kieschnick & Tobias Lühmann & Damian Kwiatkowski & Jan Meijer & Jiangfeng Du & Fazhan Shi & Friedemann Reinhard, 2021. "Robust all-optical single-shot readout of nitrogen-vacancy centers in diamond," Nature Communications, Nature, vol. 12(1), pages 1-6, December.
    8. D. Rugar & R. Budakian & H. J. Mamin & B. W. Chui, 2004. "Single spin detection by magnetic resonance force microscopy," Nature, Nature, vol. 430(6997), pages 329-332, July.
    9. G. Kucsko & P. C. Maurer & N. Y. Yao & M. Kubo & H. J. Noh & P. K. Lo & H. Park & M. D. Lukin, 2013. "Nanometre-scale thermometry in a living cell," Nature, Nature, vol. 500(7460), pages 54-58, August.
    Full references (including those not matched with items on IDEAS)

    Most related items

    These are the items that most often cite the same works as this one and are cited by the same works as this one.
    1. Alexander Savvin & Alexander Dormidonov & Evgeniya Smetanina & Vladimir Mitrokhin & Evgeniy Lipatov & Dmitriy Genin & Sergey Potanin & Alexander Yelisseyev & Viktor Vins, 2021. "NV– diamond laser," Nature Communications, Nature, vol. 12(1), pages 1-8, December.
    2. Sedmak, Ivan & Urbančič, Iztok & Podlipec, Rok & Štrancar, Janez & Mortier, Michel & Golobič, Iztok, 2016. "Submicron thermal imaging of a nucleate boiling process using fluorescence microscopy," Energy, Elsevier, vol. 109(C), pages 436-445.
    3. Jiaze Yin & Lu Lan & Yi Zhang & Hongli Ni & Yuying Tan & Meng Zhang & Yeran Bai & Ji-Xin Cheng, 2021. "Nanosecond-resolution photothermal dynamic imaging via MHZ digitization and match filtering," Nature Communications, Nature, vol. 12(1), pages 1-11, December.
    4. Elias Amselem & Bo Broadwater & Tora Hävermark & Magnus Johansson & Johan Elf, 2023. "Real-time single-molecule 3D tracking in E. coli based on cross-entropy minimization," Nature Communications, Nature, vol. 14(1), pages 1-11, December.
    5. Andrea Bucci & Giorgio Tortarolo & Marcus Oliver Held & Luca Bega & Eleonora Perego & Francesco Castagnetti & Irene Bozzoni & Eli Slenders & Giuseppe Vicidomini, 2024. "4D Single-particle tracking with asynchronous read-out single-photon avalanche diode array detector," Nature Communications, Nature, vol. 15(1), pages 1-12, December.
    6. Michael P Lake & Louis-S Bouchard, 2017. "Targeted nanodiamonds for identification of subcellular protein assemblies in mammalian cells," PLOS ONE, Public Library of Science, vol. 12(6), pages 1-18, June.
    7. Durga Bhaktavatsala Rao Dasari & Sen Yang & Arnab Chakrabarti & Amit Finkler & Gershon Kurizki & Jörg Wrachtrup, 2022. "Anti-Zeno purification of spin baths by quantum probe measurements," Nature Communications, Nature, vol. 13(1), pages 1-10, December.
    8. W. S. Huxter & M. L. Palm & M. L. Davis & P. Welter & C.-H. Lambert & M. Trassin & C. L. Degen, 2022. "Scanning gradiometry with a single spin quantum magnetometer," Nature Communications, Nature, vol. 13(1), pages 1-9, December.
    9. Yukai Wu & Fang Li & Yanan Wu & Hao Wang & Liangtao Gu & Jieying Zhang & Yukun Qi & Lingkai Meng & Na Kong & Yingjie Chai & Qian Hu & Zhenyu Xing & Wuwei Ren & Fuyou Li & Xingjun Zhu, 2024. "Lanthanide luminescence nanothermometer with working wavelength beyond 1500 nm for cerebrovascular temperature imaging in vivo," Nature Communications, Nature, vol. 15(1), pages 1-13, December.
    10. Sam Daly & João Ferreira Fernandes & Ezra Bruggeman & Anoushka Handa & Ruby Peters & Sarah Benaissa & Boya Zhang & Joseph S. Beckwith & Edward W. Sanders & Ruth R. Sims & David Klenerman & Simon J. Da, 2024. "High-density volumetric super-resolution microscopy," Nature Communications, Nature, vol. 15(1), pages 1-10, December.
    11. Ruotian Gong & Guanghui He & Xingyu Gao & Peng Ju & Zhongyuan Liu & Bingtian Ye & Erik A. Henriksen & Tongcang Li & Chong Zu, 2023. "Coherent dynamics of strongly interacting electronic spin defects in hexagonal boron nitride," Nature Communications, Nature, vol. 14(1), pages 1-10, December.

    More about this item

    Statistics

    Access and download statistics

    Corrections

    All material on this site has been provided by the respective publishers and authors. You can help correct errors and omissions. When requesting a correction, please mention this item's handle: RePEc:nat:natcom:v:14:y:2023:i:1:d:10.1038_s41467-023-41903-5. See general information about how to correct material in RePEc.

    If you have authored this item and are not yet registered with RePEc, we encourage you to do it here. This allows to link your profile to this item. It also allows you to accept potential citations to this item that we are uncertain about.

    If CitEc recognized a bibliographic reference but did not link an item in RePEc to it, you can help with this form .

    If you know of missing items citing this one, you can help us creating those links by adding the relevant references in the same way as above, for each refering item. If you are a registered author of this item, you may also want to check the "citations" tab in your RePEc Author Service profile, as there may be some citations waiting for confirmation.

    For technical questions regarding this item, or to correct its authors, title, abstract, bibliographic or download information, contact: Sonal Shukla or Springer Nature Abstracting and Indexing (email available below). General contact details of provider: http://www.nature.com .

    Please note that corrections may take a couple of weeks to filter through the various RePEc services.

    IDEAS is a RePEc service. RePEc uses bibliographic data supplied by the respective publishers.