Small molecule branched-chain ketoacid dehydrogenase kinase (BDK) inhibitors with opposing effects on BDK protein levels
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DOI: 10.1038/s41467-023-40536-y
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- Jacquelyn M. Walejko & Bridgette A. Christopher & Scott B. Crown & Guo-Fang Zhang & Adrian Pickar-Oliver & Takeshi Yoneshiro & Matthew W. Foster & Stephani Page & Stephan Vliet & Olga Ilkayeva & Micha, 2021. "Branched-chain α-ketoacids are preferentially reaminated and activate protein synthesis in the heart," Nature Communications, Nature, vol. 12(1), pages 1-14, December.
- Luca A Lotta & Robert A Scott & Stephen J Sharp & Stephen Burgess & Jian’an Luan & Therese Tillin & Amand F Schmidt & Fumiaki Imamura & Isobel D Stewart & John R B Perry & Luke Marney & Albert Koulman, 2016. "Genetic Predisposition to an Impaired Metabolism of the Branched-Chain Amino Acids and Risk of Type 2 Diabetes: A Mendelian Randomisation Analysis," PLOS Medicine, Public Library of Science, vol. 13(11), pages 1-22, November.
- Katherine A. Henzler-Wildman & Ming Lei & Vu Thai & S. Jordan Kerns & Martin Karplus & Dorothee Kern, 2007. "A hierarchy of timescales in protein dynamics is linked to enzyme catalysis," Nature, Nature, vol. 450(7171), pages 913-916, December.
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