TET2 and TET3 loss disrupts small intestine differentiation and homeostasis
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DOI: 10.1038/s41467-023-39512-3
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- Ryan Lister & Mattia Pelizzola & Robert H. Dowen & R. David Hawkins & Gary Hon & Julian Tonti-Filippini & Joseph R. Nery & Leonard Lee & Zhen Ye & Que-Minh Ngo & Lee Edsall & Jessica Antosiewicz-Bourg, 2009. "Human DNA methylomes at base resolution show widespread epigenomic differences," Nature, Nature, vol. 462(7271), pages 315-322, November.
- Adam L. Haber & Moshe Biton & Noga Rogel & Rebecca H. Herbst & Karthik Shekhar & Christopher Smillie & Grace Burgin & Toni M. Delorey & Michael R. Howitt & Yarden Katz & Itay Tirosh & Semir Beyaz & Da, 2017. "A single-cell survey of the small intestinal epithelium," Nature, Nature, vol. 551(7680), pages 333-339, November.
- Hong Ji & Lauren I. R. Ehrlich & Jun Seita & Peter Murakami & Akiko Doi & Paul Lindau & Hwajin Lee & Martin J. Aryee & Rafael A. Irizarry & Kitai Kim & Derrick J. Rossi & Matthew A. Inlay & Thomas Ser, 2010. "Comprehensive methylome map of lineage commitment from haematopoietic progenitors," Nature, Nature, vol. 467(7313), pages 338-342, September.
- Xiaojing Yue & Chan-Wang J. Lio & Daniela Samaniego-Castruita & Xiang Li & Anjana Rao, 2019. "Loss of TET2 and TET3 in regulatory T cells unleashes effector function," Nature Communications, Nature, vol. 10(1), pages 1-14, December.
- Jakob von Moltke & Ming Ji & Hong-Erh Liang & Richard M. Locksley, 2016. "Tuft-cell-derived IL-25 regulates an intestinal ILC2–epithelial response circuit," Nature, Nature, vol. 529(7585), pages 221-225, January.
- Koen Van den Berge & Hector Roux de Bézieux & Kelly Street & Wouter Saelens & Robrecht Cannoodt & Yvan Saeys & Sandrine Dudoit & Lieven Clement, 2020. "Trajectory-based differential expression analysis for single-cell sequencing data," Nature Communications, Nature, vol. 11(1), pages 1-13, December.
- Toshiro Sato & Johan H. van Es & Hugo J. Snippert & Daniel E. Stange & Robert G. Vries & Maaike van den Born & Nick Barker & Noah F. Shroyer & Marc van de Wetering & Hans Clevers, 2011. "Paneth cells constitute the niche for Lgr5 stem cells in intestinal crypts," Nature, Nature, vol. 469(7330), pages 415-418, January.
- Michael Lawrence & Wolfgang Huber & Hervé Pagès & Patrick Aboyoun & Marc Carlson & Robert Gentleman & Martin T Morgan & Vincent J Carey, 2013. "Software for Computing and Annotating Genomic Ranges," PLOS Computational Biology, Public Library of Science, vol. 9(8), pages 1-10, August.
- François Gerbe & Emmanuelle Sidot & Danielle J. Smyth & Makoto Ohmoto & Ichiro Matsumoto & Valérie Dardalhon & Pierre Cesses & Laure Garnier & Marie Pouzolles & Bénédicte Brulin & Marco Bruschi & Yvon, 2016. "Intestinal epithelial tuft cells initiate type 2 mucosal immunity to helminth parasites," Nature, Nature, vol. 529(7585), pages 226-230, January.
- Dominic Grün & Anna Lyubimova & Lennart Kester & Kay Wiebrands & Onur Basak & Nobuo Sasaki & Hans Clevers & Alexander van Oudenaarden, 2015. "Single-cell messenger RNA sequencing reveals rare intestinal cell types," Nature, Nature, vol. 525(7568), pages 251-255, September.
- Jungeun An & Edahí González-Avalos & Ashu Chawla & Mira Jeong & Isaac F. López-Moyado & Wei Li & Margaret A. Goodell & Lukas Chavez & Myunggon Ko & Anjana Rao, 2015. "Acute loss of TET function results in aggressive myeloid cancer in mice," Nature Communications, Nature, vol. 6(1), pages 1-14, December.
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