Limitations of gene editing assessments in human preimplantation embryos
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DOI: 10.1038/s41467-023-36820-6
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- Fatwa Adikusuma & Sandra Piltz & Mark A. Corbett & Michelle Turvey & Shaun R. McColl & Karla J. Helbig & Michael R. Beard & James Hughes & Richard T. Pomerantz & Paul Q. Thomas, 2018. "Large deletions induced by Cas9 cleavage," Nature, Nature, vol. 560(7717), pages 8-9, August.
- Hong Ma & Nuria Marti-Gutierrez & Sang-Wook Park & Jun Wu & Yeonmi Lee & Keiichiro Suzuki & Amy Koski & Dongmei Ji & Tomonari Hayama & Riffat Ahmed & Hayley Darby & Crystal Van Dyken & Ying Li & Eunju, 2017. "Correction of a pathogenic gene mutation in human embryos," Nature, Nature, vol. 548(7668), pages 413-419, August.
- K. Yoshimi & T. Kaneko & B. Voigt & T. Mashimo, 2014. "Allele-specific genome editing and correction of disease-associated phenotypes in rats using the CRISPR–Cas platform," Nature Communications, Nature, vol. 5(1), pages 1-9, September.
- Stamatis Papathanasiou & Styliani Markoulaki & Logan J. Blaine & Mitchell L. Leibowitz & Cheng-Zhong Zhang & Rudolf Jaenisch & David Pellman, 2021. "Whole chromosome loss and genomic instability in mouse embryos after CRISPR-Cas9 genome editing," Nature Communications, Nature, vol. 12(1), pages 1-7, December.
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