USP5-Beclin 1 axis overrides p53-dependent senescence and drives Kras-induced tumorigenicity
Author
Abstract
Suggested Citation
DOI: 10.1038/s41467-022-35557-y
Download full text from publisher
References listed on IDEAS
- Ting Sun & Xuan Li & Peng Zhang & Wen-Dan Chen & Hai-liang Zhang & Dan-Dan Li & Rong Deng & Xiao-Jun Qian & Lin Jiao & Jiao Ji & Yun-Tian Li & Rui-Yan Wu & Yan Yu & Gong-Kan Feng & Xiao-Feng Zhu, 2015. "Acetylation of Beclin 1 inhibits autophagosome maturation and promotes tumour growth," Nature Communications, Nature, vol. 6(1), pages 1-12, November.
- Lei Ji & Bo Lu & Raffaella Zamponi & Olga Charlat & Robert Aversa & Zinger Yang & Frederic Sigoillot & Xiaoping Zhu & Tiancen Hu & John S. Reece-Hoyes & Carsten Russ & Gregory Michaud & Jan S. Tchorz , 2019. "USP7 inhibits Wnt/β-catenin signaling through promoting stabilization of Axin," Nature Communications, Nature, vol. 10(1), pages 1-14, December.
- Manuel Collado & Jesús Gil & Alejo Efeyan & Carmen Guerra & Alberto J. Schuhmacher & Marta Barradas & Alberto Benguría & Angel Zaballos & Juana M. Flores & Mariano Barbacid & David Beach & Manuel Serr, 2005. "Senescence in premalignant tumours," Nature, Nature, vol. 436(7051), pages 642-642, August.
- Rebecca Aron & Pasquale Pellegrini & Edward W. Green & Daniel C. Maddison & Kwadwo Opoku-Nsiah & Ana Osório Oliveira & Jinny S. Wong & Aaron C. Daub & Flaviano Giorgini & Paul Muchowski & Steven Finkb, 2020. "Publisher Correction: Deubiquitinase Usp12 functions noncatalytically to induce autophagy and confer neuroprotection in models of Huntington’s disease," Nature Communications, Nature, vol. 11(1), pages 1-1, December.
- Rebecca Aron & Pasquale Pellegrini & Edward W. Green & Daniel C. Maddison & Kwadwo Opoku-Nsiah & Ana Osório Oliveira & Jinny S. Wong & Aaron C. Daub & Flaviano Giorgini & Paul Muchowski & Steven Finkb, 2020. "Author Correction: Deubiquitinase Usp12 functions noncatalytically to induce autophagy and confer neuroprotection in models of Huntington’s disease," Nature Communications, Nature, vol. 11(1), pages 1-1, December.
- Michael S. Lawrence & Petar Stojanov & Craig H. Mermel & James T. Robinson & Levi A. Garraway & Todd R. Golub & Matthew Meyerson & Stacey B. Gabriel & Eric S. Lander & Gad Getz, 2014. "Discovery and saturation analysis of cancer genes across 21 tumour types," Nature, Nature, vol. 505(7484), pages 495-501, January.
- Zhixun Dou & Caiyue Xu & Greg Donahue & Takeshi Shimi & Ji-An Pan & Jiajun Zhu & Andrejs Ivanov & Brian C. Capell & Adam M. Drake & Parisha P. Shah & Joseph M. Catanzaro & M. Daniel Ricketts & Trond L, 2015. "Autophagy mediates degradation of nuclear lamina," Nature, Nature, vol. 527(7576), pages 105-109, November.
Most related items
These are the items that most often cite the same works as this one and are cited by the same works as this one.- Guozhong Jiang & Zhizhong Wang & Zhenguo Cheng & Weiwei Wang & Shuangshuang Lu & Zifang Zhang & Chinedu A. Anene & Faraz Khan & Yue Chen & Emma Bailey & Huisha Xu & Yunshu Dong & Peinan Chen & Zhongxi, 2024. "The integrated molecular and histological analysis defines subtypes of esophageal squamous cell carcinoma," Nature Communications, Nature, vol. 15(1), pages 1-17, December.
- Marjan M. Naeini & Felicity Newell & Lauren G. Aoude & Vanessa F. Bonazzi & Kalpana Patel & Guy Lampe & Lambros T. Koufariotis & Vanessa Lakis & Venkateswar Addala & Olga Kondrashova & Rebecca L. John, 2023. "Multi-omic features of oesophageal adenocarcinoma in patients treated with preoperative neoadjuvant therapy," Nature Communications, Nature, vol. 14(1), pages 1-17, December.
- Qi Zhao & Feng Wang & Yan-Xing Chen & Shifu Chen & Yi-Chen Yao & Zhao-Lei Zeng & Teng-Jia Jiang & Ying-Nan Wang & Chen-Yi Wu & Ying Jing & You-Sheng Huang & Jing Zhang & Zi-Xian Wang & Ming-Ming He & , 2022. "Comprehensive profiling of 1015 patients’ exomes reveals genomic-clinical associations in colorectal cancer," Nature Communications, Nature, vol. 13(1), pages 1-17, December.
- Rotem Katzir & Noam Rudberg & Keren Yizhak, 2022. "Estimating tumor mutational burden from RNA-sequencing without a matched-normal sample," Nature Communications, Nature, vol. 13(1), pages 1-10, December.
- Martin Boström & Erik Larsson, 2022. "Somatic mutation distribution across tumour cohorts provides a signal for positive selection in cancer," Nature Communications, Nature, vol. 13(1), pages 1-9, December.
- Yidong Zhou & Changjun Wang & Hanjiang Zhu & Yan Lin & Bo Pan & Xiaohui Zhang & Xin Huang & Qianqian Xu & Yali Xu & Qiang Sun, 2016. "Diagnostic Accuracy of PIK3CA Mutation Detection by Circulating Free DNA in Breast Cancer: A Meta-Analysis of Diagnostic Test Accuracy," PLOS ONE, Public Library of Science, vol. 11(6), pages 1-15, June.
- Sumana Srivatsa & Hesam Montazeri & Gaia Bianco & Mairene Coto-Llerena & Mattia Marinucci & Charlotte K. Y. Ng & Salvatore Piscuoglio & Niko Beerenwinkel, 2022. "Discovery of synthetic lethal interactions from large-scale pan-cancer perturbation screens," Nature Communications, Nature, vol. 13(1), pages 1-15, December.
- Josh N. Vo & Yi-Mi Wu & Jeanmarie Mishler & Sarah Hall & Rahul Mannan & Lisha Wang & Yu Ning & Jin Zhou & Alexander C. Hopkins & James C. Estill & Wallace K. B. Chan & Jennifer Yesil & Xuhong Cao & Ar, 2022. "The genetic heterogeneity and drug resistance mechanisms of relapsed refractory multiple myeloma," Nature Communications, Nature, vol. 13(1), pages 1-13, December.
- Phillips, J.C., 2016. "Autoantibody recognition mechanisms of p53 epitopes," Physica A: Statistical Mechanics and its Applications, Elsevier, vol. 451(C), pages 162-170.
- François Serra & Andrea Nieto-Aliseda & Lucía Fanlo-Escudero & Llorenç Rovirosa & Mónica Cabrera-Pasadas & Aleksey Lazarenkov & Blanca Urmeneta & Alvaro Alcalde-Merino & Emanuele M. Nola & Andrei L. O, 2024. "p53 rapidly restructures 3D chromatin organization to trigger a transcriptional response," Nature Communications, Nature, vol. 15(1), pages 1-19, December.
- Meredith L. Jenkins & Harish Ranga-Prasad & Matthew A. H. Parson & Noah J. Harris & Manoj K. Rathinaswamy & John E. Burke, 2023. "Oncogenic mutations of PIK3CA lead to increased membrane recruitment driven by reorientation of the ABD, p85 and C-terminus," Nature Communications, Nature, vol. 14(1), pages 1-14, December.
- Yuan Lin & Theresa A. Ramelot & Simge Senyuz & Attila Gursoy & Hyunbum Jang & Ruth Nussinov & Ozlem Keskin & Yi Zheng, 2024. "Tumor-derived RHOA mutants interact with effectors in the GDP-bound state," Nature Communications, Nature, vol. 15(1), pages 1-14, December.
- Sebastian Carrasco Pro & Heather Hook & David Bray & Daniel Berenzy & Devlin Moyer & Meimei Yin & Adam Thomas Labadorf & Ryan Tewhey & Trevor Siggers & Juan Ignacio Fuxman Bass, 2023. "Widespread perturbation of ETS factor binding sites in cancer," Nature Communications, Nature, vol. 14(1), pages 1-15, December.
- Mark Bustoros & Shankara Anand & Romanos Sklavenitis-Pistofidis & Robert Redd & Eileen M. Boyle & Benny Zhitomirsky & Andrew J. Dunford & Yu-Tzu Tai & Selina J. Chavda & Cody Boehner & Carl Jannes Neu, 2022. "Genetic subtypes of smoldering multiple myeloma are associated with distinct pathogenic phenotypes and clinical outcomes," Nature Communications, Nature, vol. 13(1), pages 1-10, December.
- Feifei Xie & Shuzhen Luo & Dongbing Liu & Xiaojing Lu & Ming Wang & Xiaoxiao Liu & Fujian Jia & Yuzhi Pang & Yanying Shen & Chunling Zeng & Xinli Ma & Daoqiang Tang & Lin Tu & Linxi Yang & Yumei Cheng, 2024. "Genomic and transcriptomic landscape of human gastrointestinal stromal tumors," Nature Communications, Nature, vol. 15(1), pages 1-20, December.
- Zhe Jiang & YoungJun Ju & Amjad Ali & Philip E. D. Chung & Patryk Skowron & Dong-Yu Wang & Mariusz Shrestha & Huiqin Li & Jeff C. Liu & Ioulia Vorobieva & Ronak Ghanbari-Azarnier & Ethel Mwewa & Maria, 2023. "Distinct shared and compartment-enriched oncogenic networks drive primary versus metastatic breast cancer," Nature Communications, Nature, vol. 14(1), pages 1-22, December.
- Humza M. Ashraf & Brianna Fernandez & Sabrina L. Spencer, 2023. "The intensities of canonical senescence biomarkers integrate the duration of cell-cycle withdrawal," Nature Communications, Nature, vol. 14(1), pages 1-13, December.
- Mu-Kuei Shieu & Hsin-Yu Ho & Shu-Hui Lin & Yu-Sheng Lo & Chia-Chieh Lin & Yi-Ching Chuang & Ming-Ju Hsieh & Mu-Kuan Chen, 2022. "Association of KMT2C Genetic Variants with the Clinicopathologic Development of Oral Cancer," IJERPH, MDPI, vol. 19(7), pages 1-10, March.
- Yanling Liu & Jonathon Klein & Richa Bajpai & Li Dong & Quang Tran & Pandurang Kolekar & Jenny L. Smith & Rhonda E. Ries & Benjamin J. Huang & Yi-Cheng Wang & Todd A. Alonzo & Liqing Tian & Heather L., 2023. "Etiology of oncogenic fusions in 5,190 childhood cancers and its clinical and therapeutic implication," Nature Communications, Nature, vol. 14(1), pages 1-18, December.
- Donglin Ding & Alexandra M. Blee & Jianong Zhang & Yunqian Pan & Nicole A. Becker & L. James Maher & Rafael Jimenez & Liguo Wang & Haojie Huang, 2023. "Gain-of-function mutant p53 together with ERG proto-oncogene drive prostate cancer by beta-catenin activation and pyrimidine synthesis," Nature Communications, Nature, vol. 14(1), pages 1-19, December.
Corrections
All material on this site has been provided by the respective publishers and authors. You can help correct errors and omissions. When requesting a correction, please mention this item's handle: RePEc:nat:natcom:v:13:y:2022:i:1:d:10.1038_s41467-022-35557-y. See general information about how to correct material in RePEc.
If you have authored this item and are not yet registered with RePEc, we encourage you to do it here. This allows to link your profile to this item. It also allows you to accept potential citations to this item that we are uncertain about.
If CitEc recognized a bibliographic reference but did not link an item in RePEc to it, you can help with this form .
If you know of missing items citing this one, you can help us creating those links by adding the relevant references in the same way as above, for each refering item. If you are a registered author of this item, you may also want to check the "citations" tab in your RePEc Author Service profile, as there may be some citations waiting for confirmation.
For technical questions regarding this item, or to correct its authors, title, abstract, bibliographic or download information, contact: Sonal Shukla or Springer Nature Abstracting and Indexing (email available below). General contact details of provider: http://www.nature.com .
Please note that corrections may take a couple of weeks to filter through the various RePEc services.