Extensive androgen receptor enhancer heterogeneity in primary prostate cancers underlies transcriptional diversity and metastatic potential
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DOI: 10.1038/s41467-022-35135-2
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- Suzan Stelloo & Ekaterina Nevedomskaya & Yongsoo Kim & Karianne Schuurman & Eider Valle-Encinas & João Lobo & Oscar Krijgsman & Daniel Simon Peeper & Seiwon Laura Chang & Felix Yi-Chung Feng & Lodewyk, 2018. "Integrative epigenetic taxonomy of primary prostate cancer," Nature Communications, Nature, vol. 9(1), pages 1-12, December.
- Ken-ichi Takayama & Aya Misawa & Takashi Suzuki & Kiyoshi Takagi & Yoshihide Hayashizaki & Tetsuya Fujimura & Yukio Homma & Satoru Takahashi & Tomohiko Urano & Satoshi Inoue, 2015. "Correction: Corrigendum: TET2 repression by androgen hormone regulates global hydroxymethylation status and prostate cancer progression," Nature Communications, Nature, vol. 6(1), pages 1-1, December.
- Elizabeth J. Adams & Wouter R. Karthaus & Elizabeth Hoover & Deli Liu & Antoine Gruet & Zeda Zhang & Hyunwoo Cho & Rose DiLoreto & Sagar Chhangawala & Yang Liu & Philip A. Watson & Elai Davicioni & An, 2019. "FOXA1 mutations alter pioneering activity, differentiation and prostate cancer phenotypes," Nature, Nature, vol. 571(7765), pages 408-412, July.
- Catherine S. Grasso & Yi-Mi Wu & Dan R. Robinson & Xuhong Cao & Saravana M. Dhanasekaran & Amjad P. Khan & Michael J. Quist & Xiaojun Jing & Robert J. Lonigro & J. Chad Brenner & Irfan A. Asangani & B, 2012. "The mutational landscape of lethal castration-resistant prostate cancer," Nature, Nature, vol. 487(7406), pages 239-243, July.
- Tunç Morova & Daniel R. McNeill & Nada Lallous & Mehmet Gönen & Kush Dalal & David M. Wilson & Attila Gürsoy & Özlem Keskin & Nathan A. Lack, 2020. "Androgen receptor-binding sites are highly mutated in prostate cancer," Nature Communications, Nature, vol. 11(1), pages 1-10, December.
- Peng Zhang & Ji-Han Xia & Jing Zhu & Ping Gao & Yi-Jun Tian & Meijun Du & Yong-Chen Guo & Sufyan Suleman & Qin Zhang & Manish Kohli & Lori S. Tillmans & Stephen N. Thibodeau & Amy J. French & James R., 2018. "High-throughput screening of prostate cancer risk loci by single nucleotide polymorphisms sequencing," Nature Communications, Nature, vol. 9(1), pages 1-12, December.
- Caryn S. Ross-Innes & Rory Stark & Andrew E. Teschendorff & Kelly A. Holmes & H. Raza Ali & Mark J. Dunning & Gordon D. Brown & Ondrej Gojis & Ian O. Ellis & Andrew R. Green & Simak Ali & Suet-Feung C, 2012. "Differential oestrogen receptor binding is associated with clinical outcome in breast cancer," Nature, Nature, vol. 481(7381), pages 389-393, January.
- Michael Lawrence & Wolfgang Huber & Hervé Pagès & Patrick Aboyoun & Marc Carlson & Robert Gentleman & Martin T Morgan & Vincent J Carey, 2013. "Software for Computing and Annotating Genomic Ranges," PLOS Computational Biology, Public Library of Science, vol. 9(8), pages 1-10, August.
- Ken-ichi Takayama & Aya Misawa & Takashi Suzuki & Kiyoshi Takagi & Yoshihide Hayashizaki & Tetsuya Fujimura & Yukio Homma & Satoru Takahashi & Tomohiko Urano & Satoshi Inoue, 2015. "TET2 repression by androgen hormone regulates global hydroxymethylation status and prostate cancer progression," Nature Communications, Nature, vol. 6(1), pages 1-16, November.
- Hong-Jian Jin & Jonathan C. Zhao & Longtao Wu & Jung Kim & Jindan Yu, 2014. "Cooperativity and equilibrium with FOXA1 define the androgen receptor transcriptional program," Nature Communications, Nature, vol. 5(1), pages 1-14, September.
- Stanley Zhou & James R. Hawley & Fraser Soares & Giacomo Grillo & Mona Teng & Seyed Ali Madani Tonekaboni & Junjie Tony Hua & Ken J. Kron & Parisa Mazrooei & Musaddeque Ahmed & Christopher Arlidge & H, 2020. "Noncoding mutations target cis-regulatory elements of the FOXA1 plexus in prostate cancer," Nature Communications, Nature, vol. 11(1), pages 1-13, December.
- Michael Fraser & Veronica Y. Sabelnykova & Takafumi N. Yamaguchi & Lawrence E. Heisler & Julie Livingstone & Vincent Huang & Yu-Jia Shiah & Fouad Yousif & Xihui Lin & Andre P. Masella & Natalie S. Fox, 2017. "Genomic hallmarks of localized, non-indolent prostate cancer," Nature, Nature, vol. 541(7637), pages 359-364, January.
- Bianca Cioni & Anniek Zaalberg & Judy R. Beijnum & Monique H. M. Melis & Johan Burgsteden & Mauro J. Muraro & Erik Hooijberg & Dennis Peters & Ingrid Hofland & Yoni Lubeck & Jeroen Jong & Joyce Sander, 2020. "Androgen receptor signalling in macrophages promotes TREM-1-mediated prostate cancer cell line migration and invasion," Nature Communications, Nature, vol. 11(1), pages 1-17, December.
- S. Taavitsainen & N. Engedal & S. Cao & F. Handle & A. Erickson & S. Prekovic & D. Wetterskog & T. Tolonen & E. M. Vuorinen & A. Kiviaho & R. Nätkin & T. Häkkinen & W. Devlies & S. Henttinen & R. Kaar, 2021. "Single-cell ATAC and RNA sequencing reveal pre-existing and persistent cells associated with prostate cancer relapse," Nature Communications, Nature, vol. 12(1), pages 1-16, December.
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