MYC promotes immune-suppression in triple-negative breast cancer via inhibition of interferon signaling
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DOI: 10.1038/s41467-022-34000-6
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- Robert T. Manguso & Hans W. Pope & Margaret D. Zimmer & Flavian D. Brown & Kathleen B. Yates & Brian C. Miller & Natalie B. Collins & Kevin Bi & Martin W. LaFleur & Vikram R. Juneja & Sarah A. Weiss &, 2017. "In vivo CRISPR screening identifies Ptpn2 as a cancer immunotherapy target," Nature, Nature, vol. 547(7664), pages 413-418, July.
- Arkajyoti Bhattacharya & Rico D. Bense & Carlos G. Urzúa-Traslaviña & Elisabeth G. E. Vries & Marcel A. T. M. Vugt & Rudolf S. N. Fehrmann, 2020. "Transcriptional effects of copy number alterations in a large set of human cancers," Nature Communications, Nature, vol. 11(1), pages 1-12, December.
- Ekaterini Platanitis & Duygu Demiroz & Anja Schneller & Katrin Fischer & Christophe Capelle & Markus Hartl & Thomas Gossenreiter & Mathias Müller & Maria Novatchkova & Thomas Decker, 2019. "A molecular switch from STAT2-IRF9 to ISGF3 underlies interferon-induced gene transcription," Nature Communications, Nature, vol. 10(1), pages 1-17, December.
- Andrea H. Bild & Guang Yao & Jeffrey T. Chang & Quanli Wang & Anil Potti & Dawn Chasse & Mary-Beth Joshi & David Harpole & Johnathan M. Lancaster & Andrew Berchuck & John A. Olson & Jeffrey R. Marks &, 2006. "Oncogenic pathway signatures in human cancers as a guide to targeted therapies," Nature, Nature, vol. 439(7074), pages 353-357, January.
- Shane M. Harding & Joseph L. Benci & Jerome Irianto & Dennis E. Discher & Andy J. Minn & Roger A. Greenberg, 2017. "Mitotic progression following DNA damage enables pattern recognition within micronuclei," Nature, Nature, vol. 548(7668), pages 466-470, August.
- Karen J. Mackenzie & Paula Carroll & Carol-Anne Martin & Olga Murina & Adeline Fluteau & Daniel J. Simpson & Nelly Olova & Hannah Sutcliffe & Jacqueline K. Rainger & Andrea Leitch & Ruby T. Osborn & A, 2017. "cGAS surveillance of micronuclei links genome instability to innate immunity," Nature, Nature, vol. 548(7668), pages 461-465, August.
- Joshi M. Ramanjulu & G. Scott Pesiridis & Jingsong Yang & Nestor Concha & Robert Singhaus & Shu-Yun Zhang & Jean-Luc Tran & Patrick Moore & Stephanie Lehmann & H. Christian Eberl & Marcel Muelbaier & , 2018. "Design of amidobenzimidazole STING receptor agonists with systemic activity," Nature, Nature, vol. 564(7736), pages 439-443, December.
- Stefano Annunziato & Julian R. de Ruiter & Linda Henneman & Chiara S. Brambillasca & Catrin Lutz & François Vaillant & Federica Ferrante & Anne Paulien Drenth & Eline van der Burg & Bjørn Siteur & Bas, 2019. "Comparative oncogenomics identifies combinations of driver genes and drug targets in BRCA1-mutated breast cancer," Nature Communications, Nature, vol. 10(1), pages 1-12, December.
- Shashank J. Patel & Neville E. Sanjana & Rigel J. Kishton & Arash Eidizadeh & Suman K. Vodnala & Maggie Cam & Jared J. Gartner & Li Jia & Seth M. Steinberg & Tori N. Yamamoto & Anand S. Merchant & Gau, 2017. "Identification of essential genes for cancer immunotherapy," Nature, Nature, vol. 548(7669), pages 537-542, August.
- Caryn S. Ross-Innes & Rory Stark & Andrew E. Teschendorff & Kelly A. Holmes & H. Raza Ali & Mark J. Dunning & Gordon D. Brown & Ondrej Gojis & Ian O. Ellis & Andrew R. Green & Simak Ali & Suet-Feung C, 2012. "Differential oestrogen receptor binding is associated with clinical outcome in breast cancer," Nature, Nature, vol. 481(7381), pages 389-393, January.
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- Rebecca J. Austin & Jasmin Straube & Rohit Halder & Yashaswini Janardhanan & Claudia Bruedigam & Matthew Witkowski & Leanne Cooper & Amy Porter & Matthias Braun & Fernando Souza-Fonseca-Guimaraes & Si, 2023. "Oncogenic drivers dictate immune control of acute myeloid leukemia," Nature Communications, Nature, vol. 14(1), pages 1-14, December.
- Mindy K. Graham & Rulin Wang & Roshan Chikarmane & Bulouere Abel & Ajay Vaghasia & Anuj Gupta & Qizhi Zheng & Jessica Hicks & Polina Sysa-Shah & Xin Pan & Nicole Castagna & Jianyong Liu & Jennifer Mey, 2024. "Convergent alterations in the tumor microenvironment of MYC-driven human and murine prostate cancer," Nature Communications, Nature, vol. 15(1), pages 1-20, December.
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