Targeting transcription in heart failure via CDK7/12/13 inhibition
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DOI: 10.1038/s41467-022-31541-8
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- Nadine Czudnochowski & Christian A. Bösken & Matthias Geyer, 2012. "Serine-7 but not serine-5 phosphorylation primes RNA polymerase II CTD for P-TEFb recognition," Nature Communications, Nature, vol. 3(1), pages 1-12, January.
- Nicholas Kwiatkowski & Tinghu Zhang & Peter B. Rahl & Brian J. Abraham & Jessica Reddy & Scott B. Ficarro & Anahita Dastur & Arnaud Amzallag & Sridhar Ramaswamy & Bethany Tesar & Catherine E. Jenkins , 2014. "Targeting transcription regulation in cancer with a covalent CDK7 inhibitor," Nature, Nature, vol. 511(7511), pages 616-620, July.
- Florencia Cayrol & Pannee Praditsuktavorn & Tharu M. Fernando & Nicholas Kwiatkowski & Rosella Marullo & M. Nieves Calvo-Vidal & Jude Phillip & Benet Pera & Shao Ning Yang & Kaipol Takpradit & Lidia R, 2017. "THZ1 targeting CDK7 suppresses STAT transcriptional activity and sensitizes T-cell lymphomas to BCL2 inhibitors," Nature Communications, Nature, vol. 8(1), pages 1-12, April.
- Michael Alexanian & Pawel F. Przytycki & Rudi Micheletti & Arun Padmanabhan & Lin Ye & Joshua G. Travers & Barbara Gonzalez-Teran & Ana Catarina Silva & Qiming Duan & Sanjeev S. Ranade & Franco Felix , 2021. "A transcriptional switch governs fibroblast activation in heart disease," Nature, Nature, vol. 595(7867), pages 438-443, July.
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