CD8+T cell responsiveness to anti-PD-1 is epigenetically regulated by Suv39h1 in melanomas
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DOI: 10.1038/s41467-022-31504-z
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- Omar Khan & Josephine R. Giles & Sierra McDonald & Sasikanth Manne & Shin Foong Ngiow & Kunal P. Patel & Michael T. Werner & Alexander C. Huang & Katherine A. Alexander & Jennifer E. Wu & John Attanas, 2019. "TOX transcriptionally and epigenetically programs CD8+ T cell exhaustion," Nature, Nature, vol. 571(7764), pages 211-218, July.
- Francesca Alfei & Kristiyan Kanev & Maike Hofmann & Ming Wu & Hazem E. Ghoneim & Patrick Roelli & Daniel T. Utzschneider & Madlaina von Hoesslin & Jolie G. Cullen & Yiping Fan & Vasyl Eisenberg & Dirk, 2019. "TOX reinforces the phenotype and longevity of exhausted T cells in chronic viral infection," Nature, Nature, vol. 571(7764), pages 265-269, July.
- Ben Youngblood & J. Scott Hale & Haydn T. Kissick & Eunseon Ahn & Xiaojin Xu & Andreas Wieland & Koichi Araki & Erin E. West & Hazem E. Ghoneim & Yiping Fan & Pranay Dogra & Carl W. Davis & Bogumila T, 2017. "Effector CD8 T cells dedifferentiate into long-lived memory cells," Nature, Nature, vol. 552(7685), pages 404-409, December.
- Norio Chihara & Asaf Madi & Takaaki Kondo & Huiyuan Zhang & Nandini Acharya & Meromit Singer & Jackson Nyman & Nemanja D. Marjanovic & Monika S. Kowalczyk & Chao Wang & Sema Kurtulus & Travis Law & Ya, 2018. "Induction and transcriptional regulation of the co-inhibitory gene module in T cells," Nature, Nature, vol. 558(7710), pages 454-459, June.
- Andrew C. Scott & Friederike Dündar & Paul Zumbo & Smita S. Chandran & Christopher A. Klebanoff & Mojdeh Shakiba & Prerak Trivedi & Laura Menocal & Heather Appleby & Steven Camara & Dmitriy Zamarin & , 2019. "TOX is a critical regulator of tumour-specific T cell differentiation," Nature, Nature, vol. 571(7764), pages 270-274, July.
- Rhys S. Allan & Elina Zueva & Florence Cammas & Heidi A. Schreiber & Vanessa Masson & Gabrielle T. Belz & Danièle Roche & Christèle Maison & Jean-Pierre Quivy & Geneviève Almouzni & Sebastian Amigoren, 2012. "An epigenetic silencing pathway controlling T helper 2 cell lineage commitment," Nature, Nature, vol. 487(7406), pages 249-253, July.
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