IDEAS home Printed from https://ideas.repec.org/a/nat/natcom/v12y2021i1d10.1038_s41467-021-26237-4.html
   My bibliography  Save this article

Robust hemostatic bandages based on nanoclay electrospun membranes

Author

Listed:
  • Yan Cui

    (Central South University
    Central South University)

  • Zongwang Huang

    (Central South University)

  • Li Lei

    (the Third Xiangya Hospital, Central South University)

  • Qinglin Li

    (Cancer Hospital of the University of Chinese Academy of Sciences (Zhejiang Cancer Hospital)
    Chinese Academy of Sciences)

  • Jinlong Jiang

    (Huaiyin Institute of Technology)

  • Qinghai Zeng

    (the Third Xiangya Hospital, Central South University)

  • Aidong Tang

    (Central South University)

  • Huaming Yang

    (Central South University)

  • Yi Zhang

    (Central South University)

Abstract

Death from acute hemorrhage is a major problem in military conflicts, traffic accidents, and surgical procedures, et al. Achieving rapid effective hemostasis for pre-hospital care is essential to save lives in massive bleeding. An ideal hemostasis material should have those features such as safe, efficient, convenient, economical, which remains challenging and most of them cannot be achieved at the same time. In this work, we report a rapid effective nanoclay-based hemostatic membranes with nanoclay particles incorporate into polyvinylpyrrolidone (PVP) electrospun fibers. The nanoclay electrospun membrane (NEM) with 60 wt% kaolinite (KEM1.5) shows better and faster hemostatic performance in vitro and in vivo with good biocompatibility compared with most other NEMs and clay-based hemostats, benefiting from its enriched hemostatic functional sites, robust fluffy framework, and hydrophilic surface. The robust hemostatic bandages based on nanoclay electrospun membrane is an effective candidate hemostat in practical application.

Suggested Citation

  • Yan Cui & Zongwang Huang & Li Lei & Qinglin Li & Jinlong Jiang & Qinghai Zeng & Aidong Tang & Huaming Yang & Yi Zhang, 2021. "Robust hemostatic bandages based on nanoclay electrospun membranes," Nature Communications, Nature, vol. 12(1), pages 1-11, December.
    • Handle: RePEc:nat:natcom:v:12:y:2021:i:1:d:10.1038_s41467-021-26237-4
    DOI: 10.1038/s41467-021-26237-4
    as

    Download full text from publisher

    File URL: https://www.nature.com/articles/s41467-021-26237-4
    File Function: Abstract
    Download Restriction: no
    File URL: https://libkey.io/10.1038/s41467-021-26237-4?utm_source=ideas
    LibKey link: if access is restricted and if your library uses this service, LibKey will redirect you to where you can use your library subscription to access this item
    ---><---

    References listed on IDEAS

    as
    1. Xin Zhao & Baolin Guo & Hao Wu & Yongping Liang & Peter X. Ma, 2018. "Injectable antibacterial conductive nanocomposite cryogels with rapid shape recovery for noncompressible hemorrhage and wound healing," Nature Communications, Nature, vol. 9(1), pages 1-17, December.
    Full references (including those not matched with items on IDEAS)

    Most related items

    These are the items that most often cite the same works as this one and are cited by the same works as this one.
    1. Guangyu Bao & Qiman Gao & Massimo Cau & Nabil Ali-Mohamad & Mitchell Strong & Shuaibing Jiang & Zhen Yang & Amin Valiei & Zhenwei Ma & Marco Amabili & Zu-Hua Gao & Luc Mongeau & Christian Kastrup & Ji, 2022. "Liquid-infused microstructured bioadhesives halt non-compressible hemorrhage," Nature Communications, Nature, vol. 13(1), pages 1-14, December.
    2. Bin Chen & Yudong Cao & Qiaoyu Li & Zhuo Yan & Rui Liu & Yunjiao Zhao & Xiang Zhang & Minying Wu & Yixiu Qin & Chang Sun & Wei Yao & Ziyi Cao & Pulickel M. Ajayan & Mason Oliver Lam Chee & Pei Dong & , 2022. "Liquid metal-tailored gluten network for protein-based e-skin," Nature Communications, Nature, vol. 13(1), pages 1-12, December.

    More about this item

    Statistics

    Access and download statistics

    Corrections

    All material on this site has been provided by the respective publishers and authors. You can help correct errors and omissions. When requesting a correction, please mention this item's handle: RePEc:nat:natcom:v:12:y:2021:i:1:d:10.1038_s41467-021-26237-4. See general information about how to correct material in RePEc.

    If you have authored this item and are not yet registered with RePEc, we encourage you to do it here. This allows to link your profile to this item. It also allows you to accept potential citations to this item that we are uncertain about.

    If CitEc recognized a bibliographic reference but did not link an item in RePEc to it, you can help with this form .

    If you know of missing items citing this one, you can help us creating those links by adding the relevant references in the same way as above, for each refering item. If you are a registered author of this item, you may also want to check the "citations" tab in your RePEc Author Service profile, as there may be some citations waiting for confirmation.

    For technical questions regarding this item, or to correct its authors, title, abstract, bibliographic or download information, contact: Sonal Shukla or Springer Nature Abstracting and Indexing (email available below). General contact details of provider: http://www.nature.com .

    Please note that corrections may take a couple of weeks to filter through the various RePEc services.

    IDEAS is a RePEc service. RePEc uses bibliographic data supplied by the respective publishers.