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A SAS Package for Logistic Two-Phase Studies

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  • Schill, Walter
  • Enders, Dirk
  • Drescher, Karsten

Abstract

Two-phase designs, in which for a large study a dichotomous outcome and partial or proxy information on risk factors is available, whereas precise or complete measurements on covariates have been obtained only in a stratified sub-sample, extend the standard case-control design and have been proven useful in practice. The application of two-phase designs, however, seems to be hampered by the lack of appropriate, easy-to-use software. This paper introduces sas-twophase-package, a collection of SAS-macros, to fulfill this task. sas-twophase-package implements weighted likelihood, pseudo likelihood and semi- parametric maximum likelihood estimation via the EM algorithm and via profile likelihood in two-phase settings with dichotomous outcome and a given stratification.

Suggested Citation

  • Schill, Walter & Enders, Dirk & Drescher, Karsten, 2014. "A SAS Package for Logistic Two-Phase Studies," Journal of Statistical Software, Foundation for Open Access Statistics, vol. 57(i09).
    • Handle: RePEc:jss:jstsof:v:057:i09
    DOI: http://hdl.handle.net/10.18637/jss.v057.i09
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    References listed on IDEAS

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    1. N. E. Breslow & N. Chatterjee, 1999. "Design and analysis of two‐phase studies with binary outcome applied to Wilms tumour prognosis," Journal of the Royal Statistical Society Series C, Royal Statistical Society, vol. 48(4), pages 457-468.
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