IDEAS home Printed from https://ideas.repec.org/a/gam/jijerp/v9y2012i5p1732-1747d17584.html
   My bibliography  Save this article

Birth Defects in Gaza: Prevalence, Types, Familiarity and Correlation with Environmental Factors

Author

Listed:
  • Awny Naim

    (Palestinian Energy Authority, Gaza, Palestine)

  • Hedaya Al Dalies

    (Al Shifa Hospital, Gaza, Palestine)

  • Mohammed El Balawi

    (Al Shifa Hospital, Gaza, Palestine)

  • Eman Salem

    (Al Shifa Hospital, Gaza, Palestine)

  • Kholud Al Meziny

    (Al Shifa Hospital, Gaza, Palestine)

  • Raneem Al Shawwa

    (IT consultant, Gaza, Palestine)

  • Roberto Minutolo

    (Nephrology Department, University of Naples, Via Giovanni Paladino, 80138 Napoli, Italy)

  • Paola Manduca

    (Al Shifa Hospital, Gaza, Palestine
    Genetics Department, University of Genoa, C.Europa 26, 16132 Genova, Italy)

Abstract

This is the first report of registration at birth, and of incidence of major structural birth defects (BD) obtained in Gaza at Al Shifa Hospital, where 28% of total births in Gaza Strip occur. Doctors registered 4,027 deliveries, with a protocol comprehensive of clinical, demographic, kin and environmental questions. Prevalence of BD is 14/1,000, without association with intermarriage or gender of the child. Prevalence of late miscarriages and still births are respectively 23.3/1,000 and 7.4/1,000, and of premature births 19.6/1,000. Couples with a BD child have about 10 times higher frequency of recurrence of a BD in their progeny than those with normal children, but none of their 694 siblings and only 10/1,000 of their 1,423 progeny had BD, similar to the frequency in general population. These data suggest occurrence of novel genetic and epigenetic events in determination of BD. Children with BD were born with higher frequency ( p

Suggested Citation

  • Awny Naim & Hedaya Al Dalies & Mohammed El Balawi & Eman Salem & Kholud Al Meziny & Raneem Al Shawwa & Roberto Minutolo & Paola Manduca, 2012. "Birth Defects in Gaza: Prevalence, Types, Familiarity and Correlation with Environmental Factors," IJERPH, MDPI, vol. 9(5), pages 1-16, May.
    • Handle: RePEc:gam:jijerp:v:9:y:2012:i:5:p:1732-1747:d:17584
    as

    Download full text from publisher

    File URL: https://www.mdpi.com/1660-4601/9/5/1732/pdf
    Download Restriction: no
    File URL: https://www.mdpi.com/1660-4601/9/5/1732/
    Download Restriction: no
    ---><---

    References listed on IDEAS

    as
    1. M. Azim Surani, 2001. "Reprogramming of genome function through epigenetic inheritance," Nature, Nature, vol. 414(6859), pages 122-128, November.
    Full references (including those not matched with items on IDEAS)

    Citations

    Citations are extracted by the CitEc Project, subscribe to its RSS feed for this item.
    as


    Cited by:

    1. Paola Manduca & Awny Naim & Simona Signoriello, 2014. "Specific Association of Teratogen and Toxicant Metals in Hair of Newborns with Congenital Birth Defects or Developmentally Premature Birth in a Cohort of Couples with Documented Parental Exposure to M," IJERPH, MDPI, vol. 11(5), pages 1-16, May.
    2. Paola Manduca & Nabil Al Baraquni & Stefano Parodi, 2020. "Long Term Risks to Neonatal Health from Exposure to War—9 Years Long Survey of Reproductive Health and Contamination by Weapon-Delivered Heavy Metals in Gaza, Palestine," IJERPH, MDPI, vol. 17(7), pages 1-20, April.
    3. Mauro Cristaldi & Cristiano Foschi & Germana Szpunar & Carlo Brini & Fiorenzo Marinelli & Lucio Triolo, 2013. "Toxic Emissions from a Military Test Site in the Territory of Sardinia, Italy," IJERPH, MDPI, vol. 10(4), pages 1-16, April.
    4. Nabil al Baraquoni & Samir R. Qouta & Mervi Vänskä & Safwat Y. Diab & Raija-Leena Punamäki & Paola Manduca, 2020. "It Takes Time to Unravel the Ecology of War in Gaza, Palestine: Long-Term Changes in Maternal, Newborn and Toddlers’ Heavy Metal Loads, and Infant and Toddler Developmental Milestones in the Aftermath," IJERPH, MDPI, vol. 17(18), pages 1-18, September.

    Most related items

    These are the items that most often cite the same works as this one and are cited by the same works as this one.
    1. M. Samiec & M. Skrzyszowska, 2005. "Molecular conditions of the cell nucleus remodelling/reprogramming process and nuclear-transferred embryo development in the intraooplasmic karyoplast injection technique: a review," Czech Journal of Animal Science, Czech Academy of Agricultural Sciences, vol. 50(5), pages 185-195.
    2. Samira Alaani & Mozhgan Savabieasfahani & Mohammad Tafash & Paola Manduca, 2010. "Four Polygamous Families with Congenital Birth Defects from Fallujah, Iraq," IJERPH, MDPI, vol. 8(1), pages 1-8, December.

    Corrections

    All material on this site has been provided by the respective publishers and authors. You can help correct errors and omissions. When requesting a correction, please mention this item's handle: RePEc:gam:jijerp:v:9:y:2012:i:5:p:1732-1747:d:17584. See general information about how to correct material in RePEc.

    If you have authored this item and are not yet registered with RePEc, we encourage you to do it here. This allows to link your profile to this item. It also allows you to accept potential citations to this item that we are uncertain about.

    If CitEc recognized a bibliographic reference but did not link an item in RePEc to it, you can help with this form .

    If you know of missing items citing this one, you can help us creating those links by adding the relevant references in the same way as above, for each refering item. If you are a registered author of this item, you may also want to check the "citations" tab in your RePEc Author Service profile, as there may be some citations waiting for confirmation.

    For technical questions regarding this item, or to correct its authors, title, abstract, bibliographic or download information, contact: MDPI Indexing Manager (email available below). General contact details of provider: https://www.mdpi.com .

    Please note that corrections may take a couple of weeks to filter through the various RePEc services.

    IDEAS is a RePEc service. RePEc uses bibliographic data supplied by the respective publishers.