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Retinal Microvasculature and Neural Changes and Dietary Patterns in an Older Population in Southern Italy

Author

Listed:
  • Rossella Tatoli

    (National Institute of Gastroenterology—IRCCS “Saverio de Bellis”, Research Hospital, 70013 Bari, Italy)

  • Luisa Lampignano

    (National Institute of Gastroenterology—IRCCS “Saverio de Bellis”, Research Hospital, 70013 Bari, Italy)

  • Rossella Donghia

    (National Institute of Gastroenterology—IRCCS “Saverio de Bellis”, Research Hospital, 70013 Bari, Italy)

  • Alfredo Niro

    (Eye Clinic, Hospital “SS. Annunziata”, ASL Taranto, 74100 Taranto, Italy)

  • Fabio Castellana

    (National Institute of Gastroenterology—IRCCS “Saverio de Bellis”, Research Hospital, 70013 Bari, Italy)

  • Ilaria Bortone

    (Department of Translational Biomedicine and Neuroscience “DiBraiN”, University of Bari Aldo Moro, 70121 Bari, Italy)

  • Roberta Zupo

    (National Institute of Gastroenterology—IRCCS “Saverio de Bellis”, Research Hospital, 70013 Bari, Italy)

  • Sarah Tirelli

    (National Institute of Gastroenterology—IRCCS “Saverio de Bellis”, Research Hospital, 70013 Bari, Italy)

  • Madia Lozupone

    (Department of Translational Biomedicine and Neuroscience “DiBraiN”, University of Bari Aldo Moro, 70121 Bari, Italy)

  • Francesco Panza

    (Department of Translational Biomedicine and Neuroscience “DiBraiN”, University of Bari Aldo Moro, 70121 Bari, Italy)

  • Giovanni Alessio

    (Department of Translational Biomedicine and Neuroscience “DiBraiN”, University of Bari Aldo Moro, 70121 Bari, Italy)

  • Francesco Boscia

    (Department of Translational Biomedicine and Neuroscience “DiBraiN”, University of Bari Aldo Moro, 70121 Bari, Italy)

  • Giancarlo Sborgia

    (Department of Translational Biomedicine and Neuroscience “DiBraiN”, University of Bari Aldo Moro, 70121 Bari, Italy)

  • on behalf of the Eye Clinic Research Group

    (Department of Translational Biomedicine and Neuroscience “DiBraiN”, University of Bari Aldo Moro, 70121 Bari, Italy
    Membership of the Eye Clinic Research Group is provided in the Acknowledgments.)

  • Rodolfo Sardone

    (National Institute of Gastroenterology—IRCCS “Saverio de Bellis”, Research Hospital, 70013 Bari, Italy)

Abstract

Background: Like other parts of the body, the retina and its neurovascular system are also affected by age-related changes. The rising age of populations worldwide makes it important to study the pathologies related to age and their potential risk factors, such as diet and eating habits. The aim of this study was to investigate the predictive power of food groups versus retinal features among noninstitutionalized older adults from Southern Italy using a machine learning approach. Methods: We recruited 530 subjects, with a mean age of 74 years, who were drawn from the large population of the Salus in Apulia Study. In the present cross-sectional study, eating habits were assessed with a validated food frequency questionnaire. For the visual assessment, a complete ophthalmic examination and optical coherence tomography-angiography analyses were performed. Results: The analyses identified 13 out of the 28 food groups as predictors of all our retinal variables: grains, legumes, olives-vegetable oil, fruiting vegetables, other vegetables, fruits, sweets, fish, dairy, low-fat dairy, red meat, white meat, and processed meat. Conclusions: Eating habits and food consumption may be important risk factors for age-related retinal changes. A diet that provides the optimal intake of specific nutrients with antioxidant and anti-inflammatory powers, including carotenoids and omega-3 fatty acids, could have beneficial effects.

Suggested Citation

  • Rossella Tatoli & Luisa Lampignano & Rossella Donghia & Alfredo Niro & Fabio Castellana & Ilaria Bortone & Roberta Zupo & Sarah Tirelli & Madia Lozupone & Francesco Panza & Giovanni Alessio & Francesc, 2023. "Retinal Microvasculature and Neural Changes and Dietary Patterns in an Older Population in Southern Italy," IJERPH, MDPI, vol. 20(6), pages 1-17, March.
    • Handle: RePEc:gam:jijerp:v:20:y:2023:i:6:p:5108-:d:1096723
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    References listed on IDEAS

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    1. Ishwaran, Hemant & Kogalur, Udaya B. & Gorodeski, Eiran Z. & Minn, Andy J. & Lauer, Michael S., 2010. "High-Dimensional Variable Selection for Survival Data," Journal of the American Statistical Association, American Statistical Association, vol. 105(489), pages 205-217.
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