IDEAS home Printed from https://ideas.repec.org/a/gam/jijerp/v19y2022i4p2286-d751577.html
   My bibliography  Save this article

Exploring the Relationship between Frailty, Functional Status, Polypharmacy, and Quality of Life in Elderly and Middle-Aged Patients with Cardiovascular Diseases: A One-Year Follow-Up Study

Author

Listed:
  • Elisabeta Ioana Hiriscau

    (Nursing Department, Faculty of Medicine, University of Medicine and Pharmacy “Iuliu Hatieganu”, 400349 Cluj-Napoca, Romania
    Anaesthesia and Intensive Care Unit, University Clinical Municipal Hospital, 400139 Cluj-Napoca, Romania)

  • Elena-Cristina Buzdugan

    (Internal Medicine Department, Faculty of Medicine, University of Medicine and Pharmacy “Iuliu Hatieganu”, 400012 Cluj-Napoca, Romania
    Cardiology Unit, University Clinical Municipal Hospital, 400139 Cluj-Napoca, Romania)

  • Ligia-Ancuta Hui

    (Pharmaceutical Technology and Biopharmaceutics Department, Faculty of Pharmacy, University of Medicine and Pharmacy “Iuliu Hatieganu”, 400012 Cluj-Napoca, Romania
    University Clinical Municipal Hospital, 400139 Cluj-Napoca, Romania)

  • Constantin Bodolea

    (Anaesthesia and Intensive Care Unit, University Clinical Municipal Hospital, 400139 Cluj-Napoca, Romania
    Anaesthesia and Intensive Care Department, Faculty of Medicine, University of Medicine and Pharmacy “Iuliu Hatieganu”, 400012 Cluj-Napoca, Romania)

Abstract

The association between frailty, disability in activities of daily living (ADL), polypharmacy, and quality of life (QoL) in middle-aged patients with cardiovascular disease (CVD) is little investigated. This study sought (a) to explore this association comparatively in elderly and middle-aged hospitalized patients with CVD and (b) to determine which domains of ADL and QoL might improve the frailty prediction. A one-year follow-up study including 90 elderly (≥65 years old) and 89 middle-aged patients (40–65 years old) was conducted. At baseline, frailty assessment was performed based on the Fried criteria; Barthel Index (BI) and Duke Activity Status Index (DASI) were used for ADL, and European Quality of Life-5 dimensions (EQ-5D) for QoL. At follow-up, data were collected via telephone. At baseline, 79 patients (51 elderly and 28 middle-aged) were frail. The CVD frail patients showed functional dependency and a poor QoL compared to the non-frail ( p < 0.001) and within each subgroup at follow-up. Mobility was found to predict frailty in both elderly (OR = 2.34) (C.I. (1.03–5.29)) and middle-aged patients (OR = 2.58) (C.I. (1.15–5.78)). The ADL assessment and self-reported QoL may help to identify an aggravation or an advanced frailty condition in hospitalized elderly and middle-aged CVD patients.

Suggested Citation

  • Elisabeta Ioana Hiriscau & Elena-Cristina Buzdugan & Ligia-Ancuta Hui & Constantin Bodolea, 2022. "Exploring the Relationship between Frailty, Functional Status, Polypharmacy, and Quality of Life in Elderly and Middle-Aged Patients with Cardiovascular Diseases: A One-Year Follow-Up Study," IJERPH, MDPI, vol. 19(4), pages 1-18, February.
  • Handle: RePEc:gam:jijerp:v:19:y:2022:i:4:p:2286-:d:751577
    as

    Download full text from publisher

    File URL: https://www.mdpi.com/1660-4601/19/4/2286/pdf
    Download Restriction: no

    File URL: https://www.mdpi.com/1660-4601/19/4/2286/
    Download Restriction: no
    ---><---

    References listed on IDEAS

    as
    1. Inmaculada Tornero-Quiñones & Jesús Sáez-Padilla & Alejandro Espina Díaz & Manuel Tomás Abad Robles & Ángela Sierra Robles, 2020. "Functional Ability, Frailty and Risk of Falls in the Elderly: Relations with Autonomy in Daily Living," IJERPH, MDPI, vol. 17(3), pages 1-12, February.
    Full references (including those not matched with items on IDEAS)

    Most related items

    These are the items that most often cite the same works as this one and are cited by the same works as this one.
    1. Noé Labata-Lezaun & Max Canet-Vintró & Carlos López-de-Celis & Jacobo Rodríguez-Sanz & Ramón Aiguadé & Leonor Cuadra-Llopart & Esther Jovell-Fernández & Joan Bosch & Albert Pérez-Bellmunt, 2022. "Effectiveness of a Multicomponent Training Program on Physical Performance and Muscle Quality in Older Adults: A Quasi-Experimental Study," IJERPH, MDPI, vol. 20(1), pages 1-8, December.
    2. Emilio Jofré-Saldía & Álvaro Villalobos-Gorigoitía & Cristián Cofré-Bolados & Gerson Ferrari & Gemma María Gea-García, 2023. "Multicomponent Training in Progressive Phases Improves Functional Capacity, Physical Capacity, Quality of Life, and Exercise Motivation in Community-Dwelling Older Adults: A Randomized Clinical Trial," IJERPH, MDPI, vol. 20(3), pages 1-24, February.
    3. Antonio Granero-Gallegos, 2020. "New Developments in Physical Education and Sport," IJERPH, MDPI, vol. 17(24), pages 1-9, December.
    4. Alexandre Duarte Martins & Orlando Fernandes & Ana Pereira & Rafael Oliveira & Franco David Alderete Goñi & Nilton João Chantre Leite & João Paulo Brito, 2022. "The Effects of High-Speed Resistance Training on Health Outcomes in Independent Older Adults: A Systematic Review and Meta-Analysis," IJERPH, MDPI, vol. 19(9), pages 1-29, April.
    5. María Antonia Parra-Rizo & Gema Sanchís-Soler, 2021. "Physical Activity and the Improvement of Autonomy, Functional Ability, Subjective Health, and Social Relationships in Women over the Age of 60," IJERPH, MDPI, vol. 18(13), pages 1-10, June.
    6. Alejandra Segura Cardona & Doris Cardona Arango & Angela Segura Cardona & Carlos Robledo Marín & Diana Muñoz Rodríguez, 2022. "Friendly Residential Environments That Generate Autonomy in Older Persons," IJERPH, MDPI, vol. 20(1), pages 1-15, December.

    Corrections

    All material on this site has been provided by the respective publishers and authors. You can help correct errors and omissions. When requesting a correction, please mention this item's handle: RePEc:gam:jijerp:v:19:y:2022:i:4:p:2286-:d:751577. See general information about how to correct material in RePEc.

    If you have authored this item and are not yet registered with RePEc, we encourage you to do it here. This allows to link your profile to this item. It also allows you to accept potential citations to this item that we are uncertain about.

    If CitEc recognized a bibliographic reference but did not link an item in RePEc to it, you can help with this form .

    If you know of missing items citing this one, you can help us creating those links by adding the relevant references in the same way as above, for each refering item. If you are a registered author of this item, you may also want to check the "citations" tab in your RePEc Author Service profile, as there may be some citations waiting for confirmation.

    For technical questions regarding this item, or to correct its authors, title, abstract, bibliographic or download information, contact: MDPI Indexing Manager (email available below). General contact details of provider: https://www.mdpi.com .

    Please note that corrections may take a couple of weeks to filter through the various RePEc services.

    IDEAS is a RePEc service. RePEc uses bibliographic data supplied by the respective publishers.