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Economic Burden of SARS-CoV-2 Patients with Multi-Morbidity: A Systematic Review Protocol

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  • Amirah Azzeri

    (Faculty of Medicine & Health Science, Universiti Sains Islam Malaysia (USIM), Persiaran Ilmu, Bandar Baru Nilai, Nilai 71800, Negeri Sembilan, Malaysia
    Department of Research Development and Innovation, University of Malaya Medical Centre (UMMC), Lembah Pantai, Kuala Lumpur 59100, Malaysia)

  • Mohd Noor Afiq Ramlee

    (Faculty of Medicine & Health Science, Universiti Sains Islam Malaysia (USIM), Persiaran Ilmu, Bandar Baru Nilai, Nilai 71800, Negeri Sembilan, Malaysia
    Department of Research Development and Innovation, University of Malaya Medical Centre (UMMC), Lembah Pantai, Kuala Lumpur 59100, Malaysia)

  • Mohd Iqbal Mohd Noor

    (Faculty of Business Management, Universiti Teknologi MARA (UiTM) (Pahang), Raub 27600, Pahang, Malaysia
    Institute for Biodiversity and Sustainable Development, Universiti Teknologi MARA (UiTM), Shah Alam 40450, Selangor, Malaysia)

  • Mohd Hafiz Jaafar

    (Faculty of Medicine & Health Science, Universiti Sains Islam Malaysia (USIM), Persiaran Ilmu, Bandar Baru Nilai, Nilai 71800, Negeri Sembilan, Malaysia
    Department of Research Development and Innovation, University of Malaya Medical Centre (UMMC), Lembah Pantai, Kuala Lumpur 59100, Malaysia)

  • Thinni Nurul Rochmah

    (Department of Health Administration and Policy, Faculty of Public Health, Universitas Airlangga, Surabaya 60115, Jawa Timur, Indonesia)

  • Maznah Dahlui

    (Department of Research Development and Innovation, University of Malaya Medical Centre (UMMC), Lembah Pantai, Kuala Lumpur 59100, Malaysia
    Centre of Population Health, Department of Social and Preventive Medicine, Faculty of Medicine, Universiti Malaya, Kuala Lumpur 50603, Malaysia)

Abstract

Economic burden issues in SARS-CoV-2 patients with underlying co-morbidities are enormous resources for patient treatment and management. The uncertainty costs for clinical management render the healthcare system catatonic and incurs deficits in national annual budgets. This article focuses on systematic steps towards selecting and evaluating literature to uncover gaps and ways to help healthcare stakeholders optimize resources in treating and managing COVID-19 patients with multi-morbidity. A systematic review of all COVID-19 treatment procedures with co-morbidities or multi-morbidity for the period from 2019 to 2022 was conducted. The search includes studies describing treatment costs associated with multi- or co-morbidity cases for infected patients and, if concurrently reported, determining recurring expenses. Study selection will follow the Preferred Reporting Items for Systematic Reviews and Meta-Analyses (PRISMA) guidelines. Galbraith plots and I 2 statistics will be deployed to assess heterogeneity and to identify potential sources. A backward elimination process will be applied in the regression modelling procedure. Based on the number of studies retrieved and their sample size, the subgroup analysis will be stratified on participant disease category, associated total costs, and degree of freedom in cost estimation. These studies were registered in the PROSPERO registry (ID: CRD42022323071).

Suggested Citation

  • Amirah Azzeri & Mohd Noor Afiq Ramlee & Mohd Iqbal Mohd Noor & Mohd Hafiz Jaafar & Thinni Nurul Rochmah & Maznah Dahlui, 2022. "Economic Burden of SARS-CoV-2 Patients with Multi-Morbidity: A Systematic Review Protocol," IJERPH, MDPI, vol. 19(20), pages 1-11, October.
    • Handle: RePEc:gam:jijerp:v:19:y:2022:i:20:p:13157-:d:940786
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    References listed on IDEAS

    as
    1. Thinni Nurul Rochmah & Indana Tri Rahmawati & Maznah Dahlui & Wasis Budiarto & Nabilah Bilqis, 2021. "Economic Burden of Stroke Disease: A Systematic Review," IJERPH, MDPI, vol. 18(14), pages 1-16, July.
    2. Amirah Azzeri & Goh Hong Ching & Hafiz Jaafar & Mohd Iqbal Mohd Noor & Nurain Amirah Razi & Amy Yee-Hui Then & Julia Suhaimi & Fatimah Kari & Maznah Dahlui, 2020. "A Review of Published Literature Regarding Health Issues of Coastal Communities in Sabah, Malaysia," IJERPH, MDPI, vol. 17(5), pages 1-14, February.
    3. Alessandro Liberati & Douglas G Altman & Jennifer Tetzlaff & Cynthia Mulrow & Peter C Gøtzsche & John P A Ioannidis & Mike Clarke & P J Devereaux & Jos Kleijnen & David Moher, 2009. "The PRISMA Statement for Reporting Systematic Reviews and Meta-Analyses of Studies That Evaluate Health Care Interventions: Explanation and Elaboration," PLOS Medicine, Public Library of Science, vol. 6(7), pages 1-28, July.
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