IDEAS home Printed from https://ideas.repec.org/a/gam/jijerp/v18y2021i23p12370-d687133.html
   My bibliography  Save this article

Effect of Physical Activity on Cardiovascular Event Risk in a Population-Based Cohort of Patients with Type 2 Diabetes

Author

Listed:
  • Mónica Enguita-Germán

    (Unidad de Metodología, Navarrabiomed-HUN-UPNA, 31008 Pamplona, Spain
    Instituto de Investigación Sanitaria de Navarra (IdiSNA), 31008 Pamplona, Spain
    Red de Investigación en Servicios Sanitarios y Enfermedades Crónicas (REDISSEC), 48902 Bilbao, Spain)

  • Ibai Tamayo

    (Unidad de Metodología, Navarrabiomed-HUN-UPNA, 31008 Pamplona, Spain
    Instituto de Investigación Sanitaria de Navarra (IdiSNA), 31008 Pamplona, Spain
    Red de Investigación en Servicios Sanitarios y Enfermedades Crónicas (REDISSEC), 48902 Bilbao, Spain)

  • Arkaitz Galbete

    (Unidad de Metodología, Navarrabiomed-HUN-UPNA, 31008 Pamplona, Spain
    Instituto de Investigación Sanitaria de Navarra (IdiSNA), 31008 Pamplona, Spain
    Red de Investigación en Servicios Sanitarios y Enfermedades Crónicas (REDISSEC), 48902 Bilbao, Spain
    Departamento de Estadística, Universidad Pública de Navarra (UPNA), 31008 Pamplona, Spain)

  • Julián Librero

    (Unidad de Metodología, Navarrabiomed-HUN-UPNA, 31008 Pamplona, Spain
    Instituto de Investigación Sanitaria de Navarra (IdiSNA), 31008 Pamplona, Spain
    Red de Investigación en Servicios Sanitarios y Enfermedades Crónicas (REDISSEC), 48902 Bilbao, Spain)

  • Koldo Cambra

    (Red de Investigación en Servicios Sanitarios y Enfermedades Crónicas (REDISSEC), 48902 Bilbao, Spain
    Departamento de Salud, Gobierno Vasco, 01006 Vitoria-Gasteiz, Spain)

  • Berta Ibáñez-Beroiz

    (Unidad de Metodología, Navarrabiomed-HUN-UPNA, 31008 Pamplona, Spain
    Instituto de Investigación Sanitaria de Navarra (IdiSNA), 31008 Pamplona, Spain
    Red de Investigación en Servicios Sanitarios y Enfermedades Crónicas (REDISSEC), 48902 Bilbao, Spain)

Abstract

Cardiovascular disease (CVD) is the most common cause of morbidity and mortality among patients with type 2 diabetes (T2D). Physical activity (PA) is one of the few modifiable factors that can reduce this risk. The aim of this study was to estimate to what extent PA can contribute to reducing CVD risk and all-cause mortality in patients with T2D. Information from a population-based cohort including 26,587 patients with T2D from the Navarre Health System who were followed for five years was gathered from electronic clinical records. Multivariate Cox regression models were fitted to estimate the effect of PA on CVD risk and all-cause mortality, and the approach was complemented using conditional logistic regression models within a matched nested case–control design. A total of 5111 (19.2%) patients died during follow-up, which corresponds to 37.8% of the inactive group, 23.9% of the partially active group and 12.4% of the active group. CVD events occurred in 2362 (8.9%) patients, which corresponds to 11.6%, 10.1% and 7.6% of these groups. Compared with patients in the inactive group, and after matching and adjusting for confounders, the OR of having a CVD event was 0.84 (95% CI: 0.66–1.07) for the partially active group and 0.71 (95% CI: 0.56–0.91) for the active group. A slightly more pronounced gradient was obtained when focused on all-cause mortality, with ORs equal to 0.72 (95% CI: 0.61–0.85) and 0.50 (95% CI: 0.42–0.59), respectively. This study provides further evidence that physically active patients with T2D may have a reduced risk of CVD-related complications and all-cause mortality.

Suggested Citation

  • Mónica Enguita-Germán & Ibai Tamayo & Arkaitz Galbete & Julián Librero & Koldo Cambra & Berta Ibáñez-Beroiz, 2021. "Effect of Physical Activity on Cardiovascular Event Risk in a Population-Based Cohort of Patients with Type 2 Diabetes," IJERPH, MDPI, vol. 18(23), pages 1-13, November.
    • Handle: RePEc:gam:jijerp:v:18:y:2021:i:23:p:12370-:d:687133
    as

    Download full text from publisher

    File URL: https://www.mdpi.com/1660-4601/18/23/12370/pdf
    Download Restriction: no
    File URL: https://www.mdpi.com/1660-4601/18/23/12370/
    Download Restriction: no
    ---><---

    References listed on IDEAS

    as
    1. Mathilde Picard & Igor Tauveron & Salwan Magdasy & Thomas Benichou & Reza Bagheri & Ukadike C Ugbolue & Valentin Navel & Frédéric Dutheil, 2021. "Effect of exercise training on heart rate variability in type 2 diabetes mellitus patients: A systematic review and meta-analysis," PLOS ONE, Public Library of Science, vol. 16(5), pages 1-26, May.
    2. Jian Li & Johannes Siegrist, 2012. "Physical Activity and Risk of Cardiovascular Disease—A Meta-Analysis of Prospective Cohort Studies," IJERPH, MDPI, vol. 9(2), pages 1-17, January.
    Full references (including those not matched with items on IDEAS)

    Most related items

    These are the items that most often cite the same works as this one and are cited by the same works as this one.
    1. Maria Alzira Pimenta Dinis & Helder Fernando Pedrosa Sousa & Andreia de Moura & Lilian M. F. Viterbo & Ricardo J. Pinto, 2019. "Health Behaviors as a Mediator of the Association Between Interpersonal Relationships and Physical Health in a Workplace Context," IJERPH, MDPI, vol. 16(13), pages 1-9, July.
    2. Marine Kirsch & Damien Vitiello, 2022. "The COVID-19 Pandemic Lowers Active Behavior of Patients with Cardiovascular Diseases, Healthy Peoples and Athletes," IJERPH, MDPI, vol. 19(3), pages 1-14, January.
    3. Elisa Menardo & Stefano De Dominicis & Margherita Pasini, 2022. "Exploring Perceived and Objective Measures of the Neighborhood Environment and Associations with Physical Activity among Adults: A Review and a Meta-Analytic Structural Equation Model," IJERPH, MDPI, vol. 19(5), pages 1-15, February.
    4. Daniel Puciato, 2019. "Sociodemographic Associations of Physical Activity in People of Working Age," IJERPH, MDPI, vol. 16(12), pages 1-12, June.
    5. Xin Tian & Jian Fu & Jiaxue Tian & Yu Yang & Wenjie Liang & Wencui Fan & Renqing Zhao, 2021. "The Efficacy of Brief School-Based Exercise Programs in Improving Pubertal Bone Mass and Physical Fitness: A Randomized Controlled Trial," IJERPH, MDPI, vol. 18(18), pages 1-13, September.
    6. Clemens Drenowatz & Si-Tong Chen & Armando Cocca & Gerson Ferrari & Gerhard Ruedl & Klaus Greier, 2022. "Association of Body Weight and Physical Fitness during the Elementary School Years," IJERPH, MDPI, vol. 19(6), pages 1-12, March.
    7. Veronica Papa & Domenico Tafuri & Mauro Vaccarezza, 2021. "Could Physical Activity Have any Role in Cardiovascular Disease Prevention in Prisoners? A Systematic Review," IJERPH, MDPI, vol. 18(5), pages 1-18, February.
    8. Jeroen H. P. M. Van der Velde & Hans H. C. M. Savelberg & Nicolaas C. Schaper & Annemarie Koster, 2015. "Moderate Activity and Fitness, Not Sedentary Time, Are Independently Associated with Cardio-Metabolic Risk in U.S. Adults Aged 18–49," IJERPH, MDPI, vol. 12(3), pages 1-14, February.
    9. Jan Wilke & Oliver Vogel & Lutz Vogt, 2019. "Why Are You Running and Does It Hurt? Pain, Motivations and Beliefs about Injury Prevention among Participants of a Large-Scale Public Running Event," IJERPH, MDPI, vol. 16(19), pages 1-9, October.
    10. Margo Ketels & Charlotte Lund Rasmussen & Mette Korshøj & Nidhi Gupta & Dirk De Bacquer & Andreas Holtermann & Els Clays, 2020. "The Relation between Domain-Specific Physical Behaviour and Cardiorespiratory Fitness: A Cross-Sectional Compositional Data Analysis on the Physical Activity Health Paradox Using Accelerometer-Assesse," IJERPH, MDPI, vol. 17(21), pages 1-17, October.
    11. Antonio Casanova-Lizón & Agustín Manresa-Rocamora & Andrew A. Flatt & José Manuel Sarabia & Manuel Moya-Ramón, 2022. "Does Exercise Training Improve Cardiac-Parasympathetic Nervous System Activity in Sedentary People? A Systematic Review with Meta-Analysis," IJERPH, MDPI, vol. 19(21), pages 1-20, October.
    12. Takahisa Ohta & Junzo Nagashima & Hiroyuki Sasai & Naokata Ishii, 2019. "Relationship of Cardiorespiratory Fitness and Body Mass Index with the Incidence of Dyslipidemia among Japanese Women: A Cohort Study," IJERPH, MDPI, vol. 16(23), pages 1-9, November.

    Corrections

    All material on this site has been provided by the respective publishers and authors. You can help correct errors and omissions. When requesting a correction, please mention this item's handle: RePEc:gam:jijerp:v:18:y:2021:i:23:p:12370-:d:687133. See general information about how to correct material in RePEc.

    If you have authored this item and are not yet registered with RePEc, we encourage you to do it here. This allows to link your profile to this item. It also allows you to accept potential citations to this item that we are uncertain about.

    If CitEc recognized a bibliographic reference but did not link an item in RePEc to it, you can help with this form .

    If you know of missing items citing this one, you can help us creating those links by adding the relevant references in the same way as above, for each refering item. If you are a registered author of this item, you may also want to check the "citations" tab in your RePEc Author Service profile, as there may be some citations waiting for confirmation.

    For technical questions regarding this item, or to correct its authors, title, abstract, bibliographic or download information, contact: MDPI Indexing Manager (email available below). General contact details of provider: https://www.mdpi.com .

    Please note that corrections may take a couple of weeks to filter through the various RePEc services.

    IDEAS is a RePEc service. RePEc uses bibliographic data supplied by the respective publishers.