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Intermittent Fasting, Dietary Modifications, and Exercise for the Control of Gestational Diabetes and Maternal Mood Dysregulation: A Review and a Case Report

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  • Amira Mohammed Ali

    (Department of Mental Disorder Research, National Institute of Neuroscience, National Center of Neurology and Psychiatry, Tokyo 187-0031, Japan
    Department of Psychiatric Nursing and Mental Health, Faculty of Nursing, Alexandria University, Alexandria 21527, Egypt)

  • Hiroshi Kunugi

    (Department of Mental Disorder Research, National Institute of Neuroscience, National Center of Neurology and Psychiatry, Tokyo 187-0031, Japan
    Department of Psychiatry, Teikyo University School of Medicine, Tokyo 173-8605, Japan)

Abstract

Gestational diabetes mellitus (GDM) is a common pregnancy-related condition afflicting 5–36% of pregnancies. It is associated with many morbid maternal and fetal outcomes. Mood dysregulations (MDs, e.g., depression, distress, and anxiety) are common among women with GDM, and they exacerbate its prognosis and hinder its treatment. Hence, in addition to early detection and proper management of GDM, treating the associated MDs is crucial. Maternal hyperglycemia and MDs result from a complex network of genetic, behavioral, and environmental factors. This review briefly explores mechanisms that underlie GDM and prenatal MDs. It also describes the effect of exercise, dietary modification, and intermittent fasting (IF) on metabolic and affective dysfunctions exemplified by a case report. In this patient, interventions such as IF considerably reduced maternal body weight, plasma glucose, and psychological distress without any adverse effects. Thus, IF is one measure that can control GDM and maternal MDs; however, more investigations are warranted.

Suggested Citation

  • Amira Mohammed Ali & Hiroshi Kunugi, 2020. "Intermittent Fasting, Dietary Modifications, and Exercise for the Control of Gestational Diabetes and Maternal Mood Dysregulation: A Review and a Case Report," IJERPH, MDPI, vol. 17(24), pages 1-23, December.
    • Handle: RePEc:gam:jijerp:v:17:y:2020:i:24:p:9379-:d:462304
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    References listed on IDEAS

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    1. Amira Mohammed Ali & Amin Omar Hendawy, 2018. "So, Antidepressant Drugs have Serious Adverse Effects, but what are the Alternatives?," Novel Approaches in Drug Designing & Development, Juniper Publishers Inc., vol. 4(3), pages 58-69, November.
    2. Przemysław Domaszewski & Mariusz Konieczny & Paweł Pakosz & Dawid Bączkowicz & Ewa Sadowska-Krępa, 2020. "Effect of a Six-Week Intermittent Fasting Intervention Program on the Composition of the Human Body in Women over 60 Years of Age," IJERPH, MDPI, vol. 17(11), pages 1-9, June.
    3. Judit Vall Castelló & Charisse Tubianosa, 2020. "Linking Mediterranean Diet and Lifestyle with Cardio Metabolic Disease and Depressive Symptoms: A Study on the Elderly in Europe," IJERPH, MDPI, vol. 17(19), pages 1-16, September.
    4. Amira Mohammed Ali & Afaf Hassan Ahmed & Linda Smail, 2020. "Psychological Climacteric Symptoms and Attitudes toward Menopause among Emirati Women," IJERPH, MDPI, vol. 17(14), pages 1-19, July.
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    1. Amira Mohammed Ali & Abdulmajeed A. Alkhamees & Hiroaki Hori & Yoshiharu Kim & Hiroshi Kunugi, 2021. "The Depression Anxiety Stress Scale 21: Development and Validation of the Depression Anxiety Stress Scale 8-Item in Psychiatric Patients and the General Public for Easier Mental Health Measurement in ," IJERPH, MDPI, vol. 18(19), pages 1-20, September.
    2. Amira Mohammed Ali & Hiroshi Kunugi, 2021. "Approaches to Nutritional Screening in Patients with Coronavirus Disease 2019 (COVID-19)," IJERPH, MDPI, vol. 18(5), pages 1-15, March.
    3. Sohail M. Noman & Jehangir Arshad & Muhammad Zeeshan & Ateeq Ur Rehman & Amir Haider & Shahzada Khurram & Omar Cheikhrouhou & Habib Hamam & Muhammad Shafiq, 2021. "An Empirical Study on Diabetes Depression over Distress Evaluation Using Diagnosis Statistical Manual and Chi-Square Method," IJERPH, MDPI, vol. 18(7), pages 1-11, April.
    4. Amira Mohammed Ali & Amin Omar Hendawy & Abdulaziz Mofdy Almarwani & Naif Alzahrani & Nashwa Ibrahim & Abdulmajeed A. Alkhamees & Hiroshi Kunugi, 2021. "The Six-Item Version of the Internet Addiction Test: Its Development, Psychometric Properties, and Measurement Invariance among Women with Eating Disorders and Healthy School and University Students," IJERPH, MDPI, vol. 18(23), pages 1-26, November.

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