IDEAS home Printed from https://ideas.repec.org/a/gam/jijerp/v15y2018i10p2236-d175195.html
   My bibliography  Save this article

Small-Scale Variations in Urban Air Pollution Levels Are Significantly Associated with Premature Births: A Case Study in São Paulo, Brazil

Author

Listed:
  • Silvia Regina Dias Medici Saldiva

    (Centro de Pesquisa e Desenvolvimento para o SUS, Instituto de Saúde, Secretaria do Estado da Saúde de São Paulo, Rua Santo Antônio, 590-Bela Vista, São Paulo 01314-000, Brazil)

  • Ligia Vizeu Barrozo

    (Departamento de Geografia da Faculdade de Ciências, Letras e Filosofia da Universidade de São Paulo, Cidade Universitária, Av. Prof. Luciano Gualberto—Butantã, São Paulo 05344-020, Brazil
    Instituto de Estudos Avançados da Universidade de São Paulo, Rua da Praça do Relógio, 109 andar Térreo. Cidade Universitária, São Paulo 05508-050, Brazil)

  • Clea Rodrigues Leone

    (Departamento de Pediatria da Faculdade de Medicina da Universidade de São Paulo, Av. Dr. Enéas de Carvalho Aguiar, 647-Cerqueira César, São Paulo 05403-000, Brazil)

  • Marcelo Antunes Failla

    (Coordenação de Epidemiologia e Informação (CEInfo)—Secretaria Municipal da Saúde de São Paulo, R. General Jardim, 36-5º andar-Vila Buarque, São Paulo 01223-010, Brazil)

  • Eliana De Aquino Bonilha

    (Coordenação de Epidemiologia e Informação (CEInfo)—Secretaria Municipal da Saúde de São Paulo, R. General Jardim, 36-5º andar-Vila Buarque, São Paulo 01223-010, Brazil)

  • Regina Tomie Ivata Bernal

    (Núcleo de Pesquisas Epidemiológicas em Nutrição e Saúde da Faculdade de Saúde Pública da Universidade de São Paulo, Av. Dr. Arnaldo, 715-Cerqueira César, São Paulo 01246-000, Brazil)

  • Regiani Carvalho de Oliveira

    (Laboratório de Poluição Ambiental do Departamento de Patologia da Faculdade de Medicina da Universidade de São Paulo, Av. Dr. Arnaldo, 455-Cerqueira César, São Paulo 01246-903, Brazil)

  • Paulo Hilário Nascimento Saldiva

    (Instituto de Estudos Avançados da Universidade de São Paulo, Rua da Praça do Relógio, 109 andar Térreo. Cidade Universitária, São Paulo 05508-050, Brazil
    Laboratório de Poluição Ambiental do Departamento de Patologia da Faculdade de Medicina da Universidade de São Paulo, Av. Dr. Arnaldo, 455-Cerqueira César, São Paulo 01246-903, Brazil)

Abstract

Premature birth is the result of a complex interaction among genetic, epigenetic, behavioral, socioeconomic, and environmental factors. We evaluated the possible associations between air pollution and the incidence of prematurity in spatial clusters of high and low prevalence in the municipality of São Paulo. It is a spatial case-control study. The residential addresses of mothers with live births that occurred in 2012 and 2013 were geo-coded. A spatial scan statistical test performed to identify possible low-prevalence and high-prevalence clusters of premature births. After identifying, the spatial clusters were drawn samples of cases and controls in each cluster. Mothers were interviewed face-to-face using questionnaires. Air pollution exposure was assessed by passive tubes (NO 2 and O 3 ) as well as by the determination of trace elements’ concentration in tree bark. Binary logistic regression models were applied to determine the significance of the risk of premature birth. Later prenatal care, urinary infection, and hypertension were individual risk factors for prematurity. Particles produced by traffic emissions (estimated by tree bark accumulation) and photochemical pollutants involved in the photochemical cycle (estimated by O 3 and NO 2 passive tubes) also exhibited significant and robust risks for premature births. The results indicate that air pollution is an independent risk factor for prematurity.

Suggested Citation

  • Silvia Regina Dias Medici Saldiva & Ligia Vizeu Barrozo & Clea Rodrigues Leone & Marcelo Antunes Failla & Eliana De Aquino Bonilha & Regina Tomie Ivata Bernal & Regiani Carvalho de Oliveira & Paulo Hi, 2018. "Small-Scale Variations in Urban Air Pollution Levels Are Significantly Associated with Premature Births: A Case Study in São Paulo, Brazil," IJERPH, MDPI, vol. 15(10), pages 1-16, October.
    • Handle: RePEc:gam:jijerp:v:15:y:2018:i:10:p:2236-:d:175195
    as

    Download full text from publisher

    File URL: https://www.mdpi.com/1660-4601/15/10/2236/pdf
    Download Restriction: no
    File URL: https://www.mdpi.com/1660-4601/15/10/2236/
    Download Restriction: no
    ---><---

    References listed on IDEAS

    as
    1. Jichong Huang & Tingting Zhu & Yi Qu & Dezhi Mu, 2016. "Prenatal, Perinatal and Neonatal Risk Factors for Intellectual Disability: A Systemic Review and Meta-Analysis," PLOS ONE, Public Library of Science, vol. 11(4), pages 1-12, April.
    Full references (including those not matched with items on IDEAS)

    Most related items

    These are the items that most often cite the same works as this one and are cited by the same works as this one.
    1. Wafeeq Abdelaziz, Asmaa & Ibrahim Abdelmageed, Reham, 2021. "An overview of non-genetic intellectual disability among Egyptian children and adolescents," Children and Youth Services Review, Elsevier, vol. 127(C).
    2. Andrea K. Bowe & Anthony Staines & Deirdre M. Murray, 2021. "Below Average Cognitive Ability—An under Researched Risk Factor for Emotional-Behavioural Difficulties in Childhood," IJERPH, MDPI, vol. 18(24), pages 1-14, December.
    3. Michal Vostrý & Barbora Lanková & Ilona Pešatová & Otakar Fleischmann & Jaroslava Jelínková, 2022. "Nonpharmacological Compensation of Aggressive Behavior of Individuals with Moderate Intellectual Disability and Behavioral Disorders—A Case Study," IJERPH, MDPI, vol. 19(15), pages 1-12, July.

    Corrections

    All material on this site has been provided by the respective publishers and authors. You can help correct errors and omissions. When requesting a correction, please mention this item's handle: RePEc:gam:jijerp:v:15:y:2018:i:10:p:2236-:d:175195. See general information about how to correct material in RePEc.

    If you have authored this item and are not yet registered with RePEc, we encourage you to do it here. This allows to link your profile to this item. It also allows you to accept potential citations to this item that we are uncertain about.

    If CitEc recognized a bibliographic reference but did not link an item in RePEc to it, you can help with this form .

    If you know of missing items citing this one, you can help us creating those links by adding the relevant references in the same way as above, for each refering item. If you are a registered author of this item, you may also want to check the "citations" tab in your RePEc Author Service profile, as there may be some citations waiting for confirmation.

    For technical questions regarding this item, or to correct its authors, title, abstract, bibliographic or download information, contact: MDPI Indexing Manager (email available below). General contact details of provider: https://www.mdpi.com .

    Please note that corrections may take a couple of weeks to filter through the various RePEc services.

    IDEAS is a RePEc service. RePEc uses bibliographic data supplied by the respective publishers.