IDEAS home Printed from https://ideas.repec.org/a/gam/jijerp/v15y2018i10p2191-d174113.html
   My bibliography  Save this article

A Comprehensive Review of Arsenic Exposure and Risk from Rice and a Risk Assessment among a Cohort of Adolescents in Kunming, China

Author

Listed:
  • Noelle Liao

    (Department of Preventive Medicine, Keck School of Medicine, University of Southern California, Los Angeles, CA 90033, USA)

  • Edmund Seto

    (Department of Environmental & Occupational Health Sciences, School of Public Health, University of Washington, Seattle, WA 98195, USA)

  • Brenda Eskenazi

    (Department of Maternal and Child Health, School of Public Health, University of California, Berkeley, CA 94720, USA)

  • May Wang

    (Department of Community Health Sciences, School of Public Health, University of California, Los Angeles, CA 90095, USA)

  • Yan Li

    (Kunming Medical University, Kunming 650221, Yunnan, China)

  • Jenna Hua

    (Stanford Prevention Research Center, School of Medicine, Stanford University, Stanford, CA 94305, USA)

Abstract

Inorganic arsenic (iAs) is carcinogenic and highly concentrated in rice. Dietary exposure to iAs is concerning among adolescents due to their developmental stage and iAs’s long-latency effects. This paper aimed to assess iAs exposure from rice and related lifetime cancer risks (LCR) among adolescents in Kunming, China. A comprehensive literature review of iAs levels in rice and LCR in humans was also conducted. Average daily consumption of rice (ADC) was estimated from 267 adolescents (15–18 years). Rice samples obtained from 6 markets were analyzed for iAs concentration (AC). Estimated daily intake (EDI) of iAs was calculated using ADC, AC, and average body weight (BW). Lifetime Cancer Risk (LCR) was calculated using EDI and U.S. EPA derived iAs oral slope factor. The AC was 0.058 mg/kg and the average BW and ADC were 67.5 kg and 410 g/day for males and 55.5 kg and 337 g/day for females. The EDI and LCR were 3.52 × 10 −4 mg/kg-BW/day and 5.28 × 10 −4 for both males and females, with LCR 5 times above the U.S. LCR upper limit of 1.0 × 10 −4 . While the AC was below the Chinese maximum contaminant level of 0.2 mg/kg, study results indicated that Kunming adolescents may be at increased risk for iAs-related cancers.

Suggested Citation

  • Noelle Liao & Edmund Seto & Brenda Eskenazi & May Wang & Yan Li & Jenna Hua, 2018. "A Comprehensive Review of Arsenic Exposure and Risk from Rice and a Risk Assessment among a Cohort of Adolescents in Kunming, China," IJERPH, MDPI, vol. 15(10), pages 1-17, October.
  • Handle: RePEc:gam:jijerp:v:15:y:2018:i:10:p:2191-:d:174113
    as

    Download full text from publisher

    File URL: https://www.mdpi.com/1660-4601/15/10/2191/pdf
    Download Restriction: no

    File URL: https://www.mdpi.com/1660-4601/15/10/2191/
    Download Restriction: no
    ---><---

    References listed on IDEAS

    as
    1. Miwako Dakeishi & Katsuyuki Murata & Akiko Tamura & Toyoto Iwata, 2006. "Relation Between Benchmark Dose and No‐Observed‐Adverse‐Effect Level in Clinical Research: Effects of Daily Alcohol Intake on Blood Pressure in Japanese Salesmen," Risk Analysis, John Wiley & Sons, vol. 26(1), pages 115-123, February.
    2. Tomoyuki Shibata & Can Meng & Josephine Umoren & Heidi West, 2016. "Risk Assessment of Arsenic in Rice Cereal and Other Dietary Sources for Infants and Toddlers in the U.S," IJERPH, MDPI, vol. 13(4), pages 1-10, March.
    Full references (including those not matched with items on IDEAS)

    Citations

    Citations are extracted by the CitEc Project, subscribe to its RSS feed for this item.
    as


    Cited by:

    1. Shengfa F. Liao & M. Shamimul Hasan & Zhongyue Yang & Andrew W. Stevens & James Brett & Zhaohua Peng, 2020. "Feeding Arsenic-Containing Rice Bran to Growing Pigs: Growth Performance, Arsenic Tissue Distribution, and Arsenic Excretion," IJERPH, MDPI, vol. 17(22), pages 1-14, November.

    Most related items

    These are the items that most often cite the same works as this one and are cited by the same works as this one.
    1. Cristine Couto de Almeida & Diego dos Santos Baião & Paloma de Almeida Rodrigues & Tatiana Dillenburg Saint’Pierre & Rachel Ann Hauser-Davis & Katia Christina Leandro & Vania Margaret Flosi Paschoalin, 2022. "Toxic Metals and Metalloids in Infant Formulas Marketed in Brazil, and Child Health Risks According to the Target Hazard Quotients and Target Cancer Risk," IJERPH, MDPI, vol. 19(18), pages 1-14, September.
    2. Michele C. Toledo & Janice S. Lee & Bruno L. Batista & Kelly P. K. Olympio & Adelaide C. Nardocci, 2022. "Exposure to Inorganic Arsenic in Rice in Brazil: A Human Health Risk Assessment," IJERPH, MDPI, vol. 19(24), pages 1-18, December.
    3. Michele C. Toledo & Janice S. Lee & Bruno Lemos Batista & Kelly P. K. Olympio & Adelaide C. Nardocci, 2024. "Essential and Toxic Elements in Infant Cereal in Brazil: Exposure Risk Assessment," IJERPH, MDPI, vol. 21(4), pages 1-17, March.
    4. Zhuyun Gu & Shamali de Silva & Suzie M. Reichman, 2020. "Arsenic Concentrations and Dietary Exposure in Rice-Based Infant Food in Australia," IJERPH, MDPI, vol. 17(2), pages 1-11, January.
    5. Alesia C. Ferguson & Jennifer C. Black & Isaac B. Sims & Jennifer N. Welday & Samir M. Elmir & Kendra F. Goff & J. Mark Higginbotham & Helena M. Solo-Gabriele, 2018. "Risk Assessment for Children Exposed to Arsenic on Baseball Fields with Contaminated Fill Material," IJERPH, MDPI, vol. 15(1), pages 1-23, January.
    6. Yasushi Suwazono & Kouichi Sakata & Mitsuhiro Oishi & Yasushi Okubo & Mirei Dochi & Etsuko Kobayashi & Teruhiko Kido & Koji Nogawa, 2007. "Estimation of Benchmark Dose as the Threshold Amount of Alcohol Consumption for Blood Pressure in Japanese Workers," Risk Analysis, John Wiley & Sons, vol. 27(6), pages 1487-1495, December.
    7. Alesia Ferguson & Helena Solo-Gabriele, 2016. "Children’s Exposure to Environmental Contaminants: An Editorial Reflection of Articles in the IJERPH Special Issue Entitled, “Children’s Exposure to Environmental Contaminants”," IJERPH, MDPI, vol. 13(11), pages 1-10, November.

    Corrections

    All material on this site has been provided by the respective publishers and authors. You can help correct errors and omissions. When requesting a correction, please mention this item's handle: RePEc:gam:jijerp:v:15:y:2018:i:10:p:2191-:d:174113. See general information about how to correct material in RePEc.

    If you have authored this item and are not yet registered with RePEc, we encourage you to do it here. This allows to link your profile to this item. It also allows you to accept potential citations to this item that we are uncertain about.

    If CitEc recognized a bibliographic reference but did not link an item in RePEc to it, you can help with this form .

    If you know of missing items citing this one, you can help us creating those links by adding the relevant references in the same way as above, for each refering item. If you are a registered author of this item, you may also want to check the "citations" tab in your RePEc Author Service profile, as there may be some citations waiting for confirmation.

    For technical questions regarding this item, or to correct its authors, title, abstract, bibliographic or download information, contact: MDPI Indexing Manager (email available below). General contact details of provider: https://www.mdpi.com .

    Please note that corrections may take a couple of weeks to filter through the various RePEc services.

    IDEAS is a RePEc service. RePEc uses bibliographic data supplied by the respective publishers.