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Comparison of Select Analytes in Exhaled Aerosol from E-Cigarettes with Exhaled Smoke from a Conventional Cigarette and Exhaled Breaths

Author

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  • Gerald A. Long

    (Lorillard Tobacco Company, P.O. Box 21688, Greensboro, NC 27420, USA)

Abstract

Exhaled aerosols were collected following the use of two leading U.S. commercial electronic cigarettes (e-cigarettes) and a conventional cigarette by human subjects and analyzed for phenolics, carbonyls, water, glycerin and nicotine using a vacuum-assisted filter pad capture system. Exhaled breath blanks were determined for each subject prior to each product use and aerosol collection session. Distribution and mass balance of exhaled e-cigarette aerosol composition was greater than 99.9% water and glycerin, and a small amount (<0.06%) of nicotine. Total phenolic content in exhaled e-cigarette aerosol was not distinguishable from exhaled breath blanks, while total phenolics in exhaled cigarette smoke were significantly greater than in exhaled e-cigarette aerosol and exhaled breaths, averaging 66 µg/session (range 36 to 117 µg/session). The total carbonyls in exhaled e-cigarette aerosols were also not distinguishable from exhaled breaths or room air blanks. Total carbonyls in exhaled cigarette smoke was significantly greater than in exhaled e-cigarette aerosols, exhaled breath and room air blanks, averaging 242 µg/session (range 136 to 352 µg/session). These results indicate that exhaled e-cigarette aerosol does not increase bystander exposure for phenolics and carbonyls above the levels observed in exhaled breaths of air.

Suggested Citation

  • Gerald A. Long, 2014. "Comparison of Select Analytes in Exhaled Aerosol from E-Cigarettes with Exhaled Smoke from a Conventional Cigarette and Exhaled Breaths," IJERPH, MDPI, vol. 11(11), pages 1-15, October.
    • Handle: RePEc:gam:jijerp:v:11:y:2014:i:11:p:11177-11191:d:41659
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    Cited by:

    1. Alex P. Carll & Claudia Arab & Renata Salatini & Meredith D. Miles & Matthew A. Nystoriak & Kyle L. Fulghum & Daniel W. Riggs & Gregg A. Shirk & Whitney S. Theis & Nima Talebi & Aruni Bhatnagar & Dani, 2022. "E-cigarettes and their lone constituents induce cardiac arrhythmia and conduction defects in mice," Nature Communications, Nature, vol. 13(1), pages 1-16, December.
    2. Ali A. Rostami & Yezdi B. Pithawalla & Jianmin Liu & Michael J. Oldham & Karl A. Wagner & Kimberly Frost-Pineda & Mohamadi A. Sarkar, 2016. "A Well-Mixed Computational Model for Estimating Room Air Levels of Selected Constituents from E-Vapor Product Use," IJERPH, MDPI, vol. 13(8), pages 1-15, August.
    3. Grant O'Connell & Stéphane Colard & Xavier Cahours & John D. Pritchard, 2015. "An Assessment of Indoor Air Quality before, during and after Unrestricted Use of E-Cigarettes in a Small Room," IJERPH, MDPI, vol. 12(5), pages 1-19, May.
    4. Manoj Misra & Robert D. Leverette & Bethany T. Cooper & Melanee B. Bennett & Steven E. Brown, 2014. "Comparative In Vitro Toxicity Profile of Electronic and Tobacco Cigarettes, Smokeless Tobacco and Nicotine Replacement Therapy Products: E-Liquids, Extracts and Collected Aerosols," IJERPH, MDPI, vol. 11(11), pages 1-23, October.

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