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'At the point at which you can do something about it, then it becomes more relevant': Informed consent in the pharmacogenetic clinic

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  • Hedgecoe, Adam

Abstract

Sociological investigation of informed consent has generated rich and complex descriptions of the clinical encounter, often challenging the straightforward picture painted by medical ethicists. This paper builds on this work, drawing on ideas from the Sociology of Science and Technology, to explore informed consent issues surrounding the use of the drug Herceptin, widely cited as an example of a novel approach to drug development called pharmacogenetics. Drawing on qualitative semi-structured interviews with 25 UK-based breast cancer specialists, this paper explores Herceptin's disputed epistemological status, as an example of pharmacogenetics or as something out of the ordinary in terms of clinical practice. It considers how, in turn, this impacts on the way in which informed consent is sought and influenced by clinicians' desire to protect patients from possibly distressing test results. It highlights the flexible, contingent and context dependent nature of informed consent in the clinical setting.

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  • Hedgecoe, Adam, 2005. "'At the point at which you can do something about it, then it becomes more relevant': Informed consent in the pharmacogenetic clinic," Social Science & Medicine, Elsevier, vol. 61(6), pages 1201-1210, September.
    • Handle: RePEc:eee:socmed:v:61:y:2005:i:6:p:1201-1210
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    1. May, Carl & Ellis, Nicola T., 2001. "When protocols fail: technical evaluation, biomedical knowledge, and the social production of 'facts' about a telemedicine clinic," Social Science & Medicine, Elsevier, vol. 53(8), pages 989-1002, October.
    2. Fujimura, Joan H. & Chou, Danny Y., 1994. "Dissent in science: Styles of scientific practice and the controversy over the cause of AIDS," Social Science & Medicine, Elsevier, vol. 38(8), pages 1017-1036, April.
    3. Salander, Pär, 2002. "Bad news from the patient's perspective: an analysis of the written narratives of newly diagnosed cancer patients," Social Science & Medicine, Elsevier, vol. 55(5), pages 721-732, September.
    4. May, Carl & Gask, Linda & Atkinson, Theresa & Ellis, Nicola & Mair, Frances & Esmail, Aneez, 2001. "Resisting and promoting new technologies in clinical practice: the case of telepsychiatry," Social Science & Medicine, Elsevier, vol. 52(12), pages 1889-1901, June.
    5. Harth, S. C. & Thong, Y. H., 1995. "Parental perceptions and attitudes about informed consent in clinical research involving children," Social Science & Medicine, Elsevier, vol. 41(12), pages 1647-1651, December.
    6. Berg, Marc, 1997. "Problems and promises of the protocol," Social Science & Medicine, Elsevier, vol. 44(8), pages 1081-1088, April.
    7. Harth, S. C. & Thong, Y. H., 1995. "Parental perceptions and attitudes about informed consent in clinical research involving children," Social Science & Medicine, Elsevier, vol. 40(11), pages 1573-1577, June.
    8. Edwards, Sarah J. L. & Lilford, Richard J. & Thornton, Jim & Hewison, Jenny, 1998. "Informed consent for clinical trials: in search of the "best" method," Social Science & Medicine, Elsevier, vol. 47(11), pages 1825-1840, December.
    9. Kent, Gerry, 1996. "Shared understandings for informed consent: The relevance of psychological research on the provision of information," Social Science & Medicine, Elsevier, vol. 43(10), pages 1517-1523, November.
    10. Rodin, Mari, 1992. "The social construction of premenstrual syndrome," Social Science & Medicine, Elsevier, vol. 35(1), pages 49-56, July.
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    1. Gabe, Jonathan & Chamberlain, Kerry & Norris, Pauline & Dew, Kevin & Madden, Helen & Hodgetts, Darrin, 2012. "The debate about the funding of Herceptin: A case study of ‘countervailing powers’," Social Science & Medicine, Elsevier, vol. 75(12), pages 2353-2361.

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