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Early life programming of adult ischemic heart disease within and across generations: The role of the socioeconomic context

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  • Hossin, Muhammad Zakir
  • Falkstedt, Daniel
  • Allebeck, Peter
  • Mishra, Gita
  • Koupil, Ilona

Abstract

The developmental origins of ischemic heart disease (IHD) have been widely documented but little is known about their persistence across more than one generation. This study aimed to investigate whether the effects of early life disadvantages on adult IHD have changed between generations and are mediated by adult socioeconomic circumstances, and further explore the transgenerational effects of grandparental and parental exposures to disadvantaged circumstances on adult offspring's IHD.

Suggested Citation

  • Hossin, Muhammad Zakir & Falkstedt, Daniel & Allebeck, Peter & Mishra, Gita & Koupil, Ilona, 2021. "Early life programming of adult ischemic heart disease within and across generations: The role of the socioeconomic context," Social Science & Medicine, Elsevier, vol. 275(C).
    • Handle: RePEc:eee:socmed:v:275:y:2021:i:c:s027795362100143x
    DOI: 10.1016/j.socscimed.2021.113811
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    1. Greg J. Duncan & Kenneth T. H. Lee & Maria Rosales-Rueda & Ariel Kalil, 2018. "Maternal Age and Child Development," Demography, Springer;Population Association of America (PAA), vol. 55(6), pages 2229-2255, December.
    2. David W Lawson & Arijeta Makoli & Anna Goodman, 2013. "Sibling Configuration Predicts Individual and Descendant Socioeconomic Success in a Modern Post-Industrial Society," PLOS ONE, Public Library of Science, vol. 8(9), pages 1-9, September.
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    1. van Dijk, Ingrid K. & Nilsson, Therese & Quaranta, Luciana, 2024. "Disease exposure in infancy affects women's reproductive outcomes and offspring health in southern Sweden 1905–2000," Social Science & Medicine, Elsevier, vol. 347(C).

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