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Health inequalities: Embodied evidence across biological layers

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  • Vineis, Paolo
  • Delpierre, Cyrille
  • Castagné, Raphaële
  • Fiorito, Giovanni
  • McCrory, Cathal
  • Kivimaki, Mika
  • Stringhini, Silvia
  • Carmeli, Cristian
  • Kelly-Irving, Michelle

Abstract

Socioeconomic disparities have been documented in major non-communicable diseases and in their risk factors, such as obesity, hypertension, diabetes, smoking, physical inactivity, unhealthful diet and heavy drinking. However, a key research question has remained unanswered: is there a separate biological embodiment of socio-economic conditions underlying health disparities, additional and independent of those risk factors? As lifelong socioeconomic circumstances cannot be randomised, one way forward is the examination of different biological layers of evidence, including molecular changes.

Suggested Citation

  • Vineis, Paolo & Delpierre, Cyrille & Castagné, Raphaële & Fiorito, Giovanni & McCrory, Cathal & Kivimaki, Mika & Stringhini, Silvia & Carmeli, Cristian & Kelly-Irving, Michelle, 2020. "Health inequalities: Embodied evidence across biological layers," Social Science & Medicine, Elsevier, vol. 246(C).
    • Handle: RePEc:eee:socmed:v:246:y:2020:i:c:s0277953619307762
    DOI: 10.1016/j.socscimed.2019.112781
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    References listed on IDEAS

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    1. Marcus R. Munafò & George Davey Smith, 2018. "Robust research needs many lines of evidence," Nature, Nature, vol. 553(7689), pages 399-401, January.
    2. Barboza Solís, Cristina & Fantin, Romain & Castagné, Raphaële & Lang, Thierry & Delpierre, Cyrille & Kelly-Irving, Michelle, 2016. "Mediating pathways between parental socio-economic position and allostatic load in mid-life: Findings from the 1958 British birth cohort," Social Science & Medicine, Elsevier, vol. 165(C), pages 19-27.
    3. Krieger, N., 2008. "Proximal, distal, and the politics of causation: What's level got to do with it?," American Journal of Public Health, American Public Health Association, vol. 98(2), pages 221-230.
    4. Eloïse Berger & Raphaële Castagné & Marc Chadeau-Hyam & Murielle Bochud & Angelo d’Errico & Martina Gandini & Maryam Karimi & Mika Kivimäki & Vittorio Krogh & Michael Marmot & Salvatore Panico & Marti, 2019. "Multi-cohort study identifies social determinants of systemic inflammation over the life course," Nature Communications, Nature, vol. 10(1), pages 1-10, December.
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    Cited by:

    1. Jennifer Boyd & Clare Bambra & Robin C. Purshouse & John Holmes, 2021. "Beyond Behaviour: How Health Inequality Theory Can Enhance Our Understanding of the ‘Alcohol-Harm Paradox’," IJERPH, MDPI, vol. 18(11), pages 1-12, June.
    2. Oberndorfer, Moritz & Leyland, Alastair H. & Pearce, Jamie & Grabovac, Igor & Hannah, Mary K. & Dorner, Thomas E., 2023. "Unequally Unequal? Contextual-level status inequality and social cohesion moderating the association between individual-level socioeconomic position and systemic chronic inflammation," Social Science & Medicine, Elsevier, vol. 333(C).

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