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Moving from non-interventionism to industrial strategy: The roles of tentative and definitive governance in support of the UK biotech sector

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  • Hopkins, Michael M.
  • Crane, Philippa
  • Nightingale, Paul
  • Baden-Fuller, Charles

Abstract

This paper develops a framework for characterising tentative and definitive governance modes. Using investor financing of UK-based therapeutic biotech firms as a context, the paper traces how policy makers have blended tentative and definitive elements in the design and implementation of six different kinds of policies to spur investor support for these firms. We find that tentative and definitive governance are used together to balance the need for certainty with necessary responsiveness to the dynamic circumstances that surround technological emergence. Moreover we show that the relative use of tentative and definitive modes is shaped as much by higher landscape-level influences as by technology or sector-level factors. Challenges are also identified, for instance, how to maintain synergistic rather than either/or relationships between state and non-state actors when both hesitate to engage with markets at different times.

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  • Hopkins, Michael M. & Crane, Philippa & Nightingale, Paul & Baden-Fuller, Charles, 2019. "Moving from non-interventionism to industrial strategy: The roles of tentative and definitive governance in support of the UK biotech sector," Research Policy, Elsevier, vol. 48(5), pages 1113-1127.
    • Handle: RePEc:eee:respol:v:48:y:2019:i:5:p:1113-1127
    DOI: 10.1016/j.respol.2019.01.008
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    1. Lazonick,William, 1993. "Business Organization and the Myth of the Market Economy," Cambridge Books, Cambridge University Press, number 9780521447881, November.
    2. Bronwyn Hall, 2004. "The financing of research and development," Chapters, in: Anthony Bartzokas & Sunil Mani (ed.), Financial Systems, Corporate Investment in Innovation, and Venture Capital, chapter 2, Edward Elgar Publishing.
    3. Salter, Ammon J. & Martin, Ben R., 2001. "The economic benefits of publicly funded basic research: a critical review," Research Policy, Elsevier, vol. 30(3), pages 509-532, March.
    4. Rotolo, Daniele & Hicks, Diana & Martin, Ben R., 2015. "What is an emerging technology?," Research Policy, Elsevier, vol. 44(10), pages 1827-1843.
    5. Michael M. Hopkins & Philippa A. Crane & Paul Nightingale & Charles Baden-Fuller, 2013. "Buying big into biotech: scale, financing, and the industrial dynamics of UK biotech, 1980--2009," Industrial and Corporate Change, Oxford University Press and the Associazione ICC, vol. 22(4), pages 903-952, August.
    6. Arthur, W Brian, 1989. "Competing Technologies, Increasing Returns, and Lock-In by Historical Events," Economic Journal, Royal Economic Society, vol. 99(394), pages 116-131, March.
    7. Owen, Geoffrey & Hopkins, Michael M., 2016. "Science, the State and the City: Britain's Struggle to Succeed in Biotechnology," OUP Catalogue, Oxford University Press, number 9780198728009, Decembrie.
    8. Jacqueline Senker, 2004. "Trends and gaps in biotechnology policies in European Member States since 1994," Science and Public Policy, Oxford University Press, vol. 31(5), pages 385-395, October.
    9. Hopkins, Michael M. & Nightingale, Paul, 2006. "Strategic risk management using complementary assets: Organizational capabilities and the commercialization of human genetic testing in the UK," Research Policy, Elsevier, vol. 35(3), pages 355-374, April.
    10. Philip Scranton, 2006. "Technology, science and American innovation," Business History, Taylor & Francis Journals, vol. 48(3), pages 311-331.
    11. Luigi Orsenigo, 2016. "Industrial Policies for Biotechnology: Limits and New Perspectives," Politica economica, Società editrice il Mulino, issue 2, pages 253-296.
    12. Paul Westhead & David Storey, 1997. "Financial constraints on the growth of high technology small firms in the United Kingdom," Applied Financial Economics, Taylor & Francis Journals, vol. 7(2), pages 197-201.
    13. Reinhart, Carmen & Kirkegaard, Jacob & Sbrancia, Belen, 2011. "Financial repression redux," MPRA Paper 31641, University Library of Munich, Germany.
    14. Valérie Revest & Sandro Sapio, 2008. "Financing Technology-Based Small Firms in Europe: a review of the empirical evidence," LEM Papers Series 2008/23, Laboratory of Economics and Management (LEM), Sant'Anna School of Advanced Studies, Pisa, Italy.
    15. Ramjerdi, Farideh & Fearnley, Nils, 2014. "Risk and irreversibility of transport interventions," Transportation Research Part A: Policy and Practice, Elsevier, vol. 60(C), pages 31-39.
    16. Nathan ROSENBERG, 2009. "Why do firms do basic research (with their own money)?," World Scientific Book Chapters, in: Nathan Rosenberg (ed.), Studies On Science And The Innovation Process Selected Works of Nathan Rosenberg, chapter 11, pages 225-234, World Scientific Publishing Co. Pte. Ltd..
    17. Rogge, Karoline S. & Reichardt, Kristin, 2016. "Policy mixes for sustainability transitions: An extended concept and framework for analysis," Research Policy, Elsevier, vol. 45(8), pages 1620-1635.
    18. Chris Freeman & Luc Soete, 1997. "The Economics of Industrial Innovation, 3rd Edition," MIT Press Books, The MIT Press, edition 3, volume 1, number 0262061953, December.
    19. Kuhlmann, Stefan & Stegmaier, Peter & Konrad, Kornelia, 2019. "The tentative governance of emerging science and technology—A conceptual introduction," Research Policy, Elsevier, vol. 48(5), pages 1091-1097.
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    1. Kuhlmann, Stefan & Stegmaier, Peter & Konrad, Kornelia, 2019. "The tentative governance of emerging science and technology—A conceptual introduction," Research Policy, Elsevier, vol. 48(5), pages 1091-1097.
    2. Gilding, Michael & Brennecke, Julia & Bunton, Vikki & Lusher, Dean & Molloy, Peter L. & Codoreanu, Alex, 2020. "Network failure: Biotechnology firms, clusters and collaborations far from the world superclusters," Research Policy, Elsevier, vol. 49(2).
    3. Josie Coburn & Frederique Bone & Andy C. Stirling & Michael M. Hopkins & Jorge Mestre-Ferrandiz & Stathis Arapostathis & Martin J. Llewelyn, 2021. "Appraising research policy instrument mixes: a multicriteria mapping study in six European countries of diagnostic innovation to manage antimicrobial resistance," SPRU Working Paper Series 2021-03, SPRU - Science Policy Research Unit, University of Sussex Business School.
    4. Coburn, Josie & Bone, Frederique & Hopkins, Michael M. & Stirling, Andy & Mestre-Ferrandiz, Jorge & Arapostathis, Stathis & Llewelyn, Martin J., 2021. "Appraising research policy instrument mixes: a multicriteria mapping study in six European countries of diagnostic innovation to manage antimicrobial resistance," Research Policy, Elsevier, vol. 50(4).
    5. Child, John & Narooz, Rose & Hsieh, Linda & Elbanna, Said & Karmowska, Joanna & Marinova, Svetla & Puthusserry, Pushyarag & Tsai, Terence & Zhang, Yunlu, 2022. "External resource provision and the international performance of SMEs – A contextual analysis," Journal of International Management, Elsevier, vol. 28(3).
    6. Borrás, Susana & Edler, Jakob, 2020. "The roles of the state in the governance of socio-technical systems’ transformation," Research Policy, Elsevier, vol. 49(5).

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