IDEAS home Printed from https://ideas.repec.org/a/eee/matcom/v221y2024icp337-357.html
   My bibliography  Save this article

Role of ART and PrEP treatments in a stochastic HIV/AIDS epidemic model

Author

Listed:
  • Luo, Yantao
  • Huang, Jianhua
  • Teng, Zhidong
  • Liu, Qun

Abstract

In this paper, a stochastic HIV/AIDS epidemic model is presented to study the synthetic effect of ART (antiretroviral therapy) and PrEP (pre-exposure prophylaxis) treatments among MSM ( men who have sex with men). Firstly, we give the global stability of disease-free equilibrium and the endemic equilibrium in terms of basic reproduction number R0 for deterministic model. And then the existence of global positive solutions and the existence of unique ergodic stationary distribution under R0S>1 for stochastic model are given. Further, the long-time stochastic dynamic of the model is investigated, including the criteria on the extinction and persistence in mean for the stochastic model. Finally, we give some numerical simulations to illustrate our theoretical results, and the sensitive analysis shows that ART (antiretroviral therapy) and PrEP (pre-exposure prophylaxis) treatments can effectively control the spread of AIDS among MSM population.

Suggested Citation

  • Luo, Yantao & Huang, Jianhua & Teng, Zhidong & Liu, Qun, 2024. "Role of ART and PrEP treatments in a stochastic HIV/AIDS epidemic model," Mathematics and Computers in Simulation (MATCOM), Elsevier, vol. 221(C), pages 337-357.
    • Handle: RePEc:eee:matcom:v:221:y:2024:i:c:p:337-357
    DOI: 10.1016/j.matcom.2024.03.010
    as

    Download full text from publisher

    File URL: http://www.sciencedirect.com/science/article/pii/S0378475424000909
    Download Restriction: Full text for ScienceDirect subscribers only
    File URL: https://libkey.io/10.1016/j.matcom.2024.03.010?utm_source=ideas
    LibKey link: if access is restricted and if your library uses this service, LibKey will redirect you to where you can use your library subscription to access this item
    ---><---

    As the access to this document is restricted, you may want to search for a different version of it.

    References listed on IDEAS

    as
    1. Tan, Yiping & Cai, Yongli & Sun, Xiaodan & Wang, Kai & Yao, Ruoxia & Wang, Weiming & Peng, Zhihang, 2022. "A stochastic SICA model for HIV/AIDS transmission," Chaos, Solitons & Fractals, Elsevier, vol. 165(P1).
    2. Liu, Qun & Jiang, Daqing, 2020. "Dynamical behavior of a higher order stochastically perturbed HIV/AIDS model with differential infectivity and amelioration," Chaos, Solitons & Fractals, Elsevier, vol. 141(C).
    3. Zhao, Yanan & Jiang, Daqing & O’Regan, Donal, 2013. "The extinction and persistence of the stochastic SIS epidemic model with vaccination," Physica A: Statistical Mechanics and its Applications, Elsevier, vol. 392(20), pages 4916-4927.
    4. Zhai, Xuanpei & Li, Wenshuang & Wei, Fengying & Mao, Xuerong, 2023. "Dynamics of an HIV/AIDS transmission model with protection awareness and fluctuations," Chaos, Solitons & Fractals, Elsevier, vol. 169(C).
    5. Chen, Yiliang & Wen, Buyu & Teng, Zhidong, 2018. "The global dynamics for a stochastic SIS epidemic model with isolation," Physica A: Statistical Mechanics and its Applications, Elsevier, vol. 492(C), pages 1604-1624.
    Full references (including those not matched with items on IDEAS)

    Most related items

    These are the items that most often cite the same works as this one and are cited by the same works as this one.
    1. Tan, Yiping & Cai, Yongli & Sun, Xiaodan & Wang, Kai & Yao, Ruoxia & Wang, Weiming & Peng, Zhihang, 2022. "A stochastic SICA model for HIV/AIDS transmission," Chaos, Solitons & Fractals, Elsevier, vol. 165(P1).
    2. Yassine Sabbar & Mehmet Yavuz & Fatma Özköse, 2022. "Infection Eradication Criterion in a General Epidemic Model with Logistic Growth, Quarantine Strategy, Media Intrusion, and Quadratic Perturbation," Mathematics, MDPI, vol. 10(22), pages 1-16, November.
    3. Chang, Zhengbo & Meng, Xinzhu & Lu, Xiao, 2017. "Analysis of a novel stochastic SIRS epidemic model with two different saturated incidence rates," Physica A: Statistical Mechanics and its Applications, Elsevier, vol. 472(C), pages 103-116.
    4. Alkhazzan, Abdulwasea & Wang, Jungang & Nie, Yufeng & Khan, Hasib & Alzabut, Jehad, 2023. "An effective transport-related SVIR stochastic epidemic model with media coverage and Lévy noise," Chaos, Solitons & Fractals, Elsevier, vol. 175(P1).
    5. Zhao, Dianli & Zhang, Tiansi & Yuan, Sanling, 2016. "The threshold of a stochastic SIVS epidemic model with nonlinear saturated incidence," Physica A: Statistical Mechanics and its Applications, Elsevier, vol. 443(C), pages 372-379.
    6. Wen, Buyu & Teng, Zhidong & Li, Zhiming, 2018. "The threshold of a periodic stochastic SIVS epidemic model with nonlinear incidence," Physica A: Statistical Mechanics and its Applications, Elsevier, vol. 508(C), pages 532-549.
    7. Zhang, Xinhong & Jiang, Daqing & Hayat, Tasawar & Ahmad, Bashir, 2017. "Dynamical behavior of a stochastic SVIR epidemic model with vaccination," Physica A: Statistical Mechanics and its Applications, Elsevier, vol. 483(C), pages 94-108.
    8. Rifhat, Ramziya & Wang, Lei & Teng, Zhidong, 2017. "Dynamics for a class of stochastic SIS epidemic models with nonlinear incidence and periodic coefficients," Physica A: Statistical Mechanics and its Applications, Elsevier, vol. 481(C), pages 176-190.
    9. Wang, Liang & Jiang, Daqing, 2017. "Periodic solution for the stochastic chemostat with general response function," Physica A: Statistical Mechanics and its Applications, Elsevier, vol. 486(C), pages 378-385.
    10. Cao, Boqiang & Shan, Meijing & Zhang, Qimin & Wang, Weiming, 2017. "A stochastic SIS epidemic model with vaccination," Physica A: Statistical Mechanics and its Applications, Elsevier, vol. 486(C), pages 127-143.
    11. Zhai, Xuanpei & Li, Wenshuang & Wei, Fengying & Mao, Xuerong, 2023. "Dynamics of an HIV/AIDS transmission model with protection awareness and fluctuations," Chaos, Solitons & Fractals, Elsevier, vol. 169(C).
    12. Jin, Manli, 2019. "Classification of asymptotic behavior in a stochastic SIS epidemic model with vaccination," Physica A: Statistical Mechanics and its Applications, Elsevier, vol. 521(C), pages 661-666.
    13. Wen, Buyu & Rifhat, Ramziya & Teng, Zhidong, 2019. "The stationary distribution in a stochastic SIS epidemic model with general nonlinear incidence," Physica A: Statistical Mechanics and its Applications, Elsevier, vol. 524(C), pages 258-271.
    14. Zhang, Xinhong & Jiang, Daqing & Hayat, Tasawar & Ahmad, Bashir, 2017. "Dynamics of a stochastic SIS model with double epidemic diseases driven by Lévy jumps," Physica A: Statistical Mechanics and its Applications, Elsevier, vol. 471(C), pages 767-777.
    15. Xu, Xin & Tian, Baodan & Chen, Xingzhi & Qiu, Yanhong, 2024. "Dynamics of a stochastic food chain chemostat model with Monod–Haldane functional response and Ornstein–Uhlenbeck process," Mathematics and Computers in Simulation (MATCOM), Elsevier, vol. 225(C), pages 495-512.
    16. Lin, Yuguo & Jiang, Daqing & Wang, Shuai, 2014. "Stationary distribution of a stochastic SIS epidemic model with vaccination," Physica A: Statistical Mechanics and its Applications, Elsevier, vol. 394(C), pages 187-197.
    17. Wei, Fengying & Chen, Lihong, 2020. "Extinction and stationary distribution of an epidemic model with partial vaccination and nonlinear incidence rate," Physica A: Statistical Mechanics and its Applications, Elsevier, vol. 545(C).
    18. Nafiseh Shamsi Gamchi & S. Ali Torabi & Fariborz Jolai, 2021. "A novel vehicle routing problem for vaccine distribution using SIR epidemic model," OR Spectrum: Quantitative Approaches in Management, Springer;Gesellschaft für Operations Research e.V., vol. 43(1), pages 155-188, March.
    19. Cao, Zhongwei & Feng, Wei & Wen, Xiangdan & Zu, Li, 2019. "Dynamical behavior of a stochastic SEI epidemic model with saturation incidence and logistic growth," Physica A: Statistical Mechanics and its Applications, Elsevier, vol. 523(C), pages 894-907.
    20. Rajasekar, S.P. & Pitchaimani, M., 2019. "Qualitative analysis of stochastically perturbed SIRS epidemic model with two viruses," Chaos, Solitons & Fractals, Elsevier, vol. 118(C), pages 207-221.

    Corrections

    All material on this site has been provided by the respective publishers and authors. You can help correct errors and omissions. When requesting a correction, please mention this item's handle: RePEc:eee:matcom:v:221:y:2024:i:c:p:337-357. See general information about how to correct material in RePEc.

    If you have authored this item and are not yet registered with RePEc, we encourage you to do it here. This allows to link your profile to this item. It also allows you to accept potential citations to this item that we are uncertain about.

    If CitEc recognized a bibliographic reference but did not link an item in RePEc to it, you can help with this form .

    If you know of missing items citing this one, you can help us creating those links by adding the relevant references in the same way as above, for each refering item. If you are a registered author of this item, you may also want to check the "citations" tab in your RePEc Author Service profile, as there may be some citations waiting for confirmation.

    For technical questions regarding this item, or to correct its authors, title, abstract, bibliographic or download information, contact: Catherine Liu (email available below). General contact details of provider: http://www.journals.elsevier.com/mathematics-and-computers-in-simulation/ .

    Please note that corrections may take a couple of weeks to filter through the various RePEc services.

    IDEAS is a RePEc service. RePEc uses bibliographic data supplied by the respective publishers.