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Root-n estimability of some missing data models

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  • Yuan, Ao
  • Xu, Jinfeng
  • Zheng, Gang

Abstract

It is known that in many missing data models, for example, survival data models, some parameters are root-n estimable while the others are not. When they are, their limiting distributions are often Gaussian and easy to use. When they are not, their limiting distributions, if exists, are often non-Gaussian and difficult to evaluate. Thus it is important to have some preliminary assessments of the root-n estimability in these models. In this article, we study this problem for four missing data models: two-point interval censoring, double censoring, interval truncation, and a case-control genetic association model. For the first three models, we identify some parameters which are not root-n estimable. For some root-n estimable parameters, we derive the corresponding information bounds when they exist. Also, as the Cox regression model is commonly used for such data, we give asymptotic efficient information for these regression parameters. For the case-control genetic association model, we compute the asymptotic efficient information and relative efficiency, in relation to that of the full data, when only the case-control status data are available, as is often the case in practice.

Suggested Citation

  • Yuan, Ao & Xu, Jinfeng & Zheng, Gang, 2012. "Root-n estimability of some missing data models," Journal of Multivariate Analysis, Elsevier, vol. 106(C), pages 147-166.
  • Handle: RePEc:eee:jmvana:v:106:y:2012:i:c:p:147-166
    DOI: 10.1016/j.jmva.2011.11.007
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    References listed on IDEAS

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    1. Chen, Kani & Guo, Shaojun & Sun, Liuquan & Wang, Jane-Ling, 2010. "Global Partial Likelihood for Nonparametric Proportional Hazards Models," Journal of the American Statistical Association, American Statistical Association, vol. 105(490), pages 750-760.
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    3. J. Huang & J. A. Wellner, 1995. "Asymptotic normality of the NPMLE of linear functionals for interval censored data, case 1," Statistica Neerlandica, Netherlands Society for Statistics and Operations Research, vol. 49(2), pages 153-163, July.
    4. R.D. Gill, 1980. "Censoring and Stochastic Integrals," Statistica Neerlandica, Netherlands Society for Statistics and Operations Research, vol. 34(2), pages 124-124, June.
    5. Xia, Yingcun & Zhang, Dixin & Xu, Jinfeng, 2010. "Dimension Reduction and Semiparametric Estimation of Survival Models," Journal of the American Statistical Association, American Statistical Association, vol. 105(489), pages 278-290.
    6. Mai Zhou, 2005. "Empirical likelihood analysis of the rank estimator for the censored accelerated failure time model," Biometrika, Biometrika Trust, vol. 92(2), pages 492-498, June.
    7. Ishwaran, Hemant & Kogalur, Udaya B. & Gorodeski, Eiran Z. & Minn, Andy J. & Lauer, Michael S., 2010. "High-Dimensional Variable Selection for Survival Data," Journal of the American Statistical Association, American Statistical Association, vol. 105(489), pages 205-217.
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