IDEAS home Printed from https://ideas.repec.org/a/eee/infome/v2y2008i4p341-353.html
   My bibliography  Save this article

Biomedical innovation at the laboratory, clinical and commercial interface: A new method for mapping research projects, publications and patents in the field of microarrays

Author

Listed:
  • Mogoutov, Andrei
  • Cambrosio, Alberto
  • Keating, Peter
  • Mustar, Philippe

Abstract

Using the example of microarrays, one of the constitutive technologies of post-genomic biomedicine, this paper introduces a method for analyzing publications, patents and research grants as proxies for “triple-helix interfaces” between university, industry and government activities. Our method creates bridges that allow one to move seamlessly between publication, patent and research project databases that use different fields and formats, and contain different information. These links do not require pre-defined categories in order to search for correspondences between sub-topics or research areas in the three databases. Finally, our results are not restricted to quantitative information but, rather, allow one to carry out qualitative investigations of the content of research activities. Our approach draws on a combination of text-mining and network analysis/mapping software packages.

Suggested Citation

  • Mogoutov, Andrei & Cambrosio, Alberto & Keating, Peter & Mustar, Philippe, 2008. "Biomedical innovation at the laboratory, clinical and commercial interface: A new method for mapping research projects, publications and patents in the field of microarrays," Journal of Informetrics, Elsevier, vol. 2(4), pages 341-353.
    • Handle: RePEc:eee:infome:v:2:y:2008:i:4:p:341-353
    DOI: 10.1016/j.joi.2008.06.005
    as

    Download full text from publisher

    File URL: http://www.sciencedirect.com/science/article/pii/S1751157708000333
    Download Restriction: Full text for ScienceDirect subscribers only
    File URL: https://libkey.io/10.1016/j.joi.2008.06.005?utm_source=ideas
    LibKey link: if access is restricted and if your library uses this service, LibKey will redirect you to where you can use your library subscription to access this item
    ---><---

    As the access to this document is restricted, you may want to search for a different version of it.

    References listed on IDEAS

    as
    1. Eric von Hippel, 1986. "Lead Users: A Source of Novel Product Concepts," Management Science, INFORMS, vol. 32(7), pages 791-805, July.
    2. Philippe Mustar, 1997. "How French academics create hi-tech companies: The conditions for success or failure," Science and Public Policy, Oxford University Press, vol. 24(1), pages 37-43, February.
    3. von Hippel, Eric, 1976. "The dominant role of users in the scientific instrument innovation process," Research Policy, Elsevier, vol. 5(3), pages 212-239, July.
    4. Fransman, Martin, 2001. "Designing Dolly: interactions between economics, technology and science and the evolution of hybrid institutions," Research Policy, Elsevier, vol. 30(2), pages 263-273, February.
    5. Arnold Verbeek & Koenraad Debackere & Marc Luwel & Petra Andries & Edwin Zimmermann & Filip Deleus, 2002. "Linking science to technology: Using bibliographic references in patents to build linkage schemes," Scientometrics, Springer;Akadémiai Kiadó, vol. 54(3), pages 399-420, July.
    6. Arnold Verbeek & Koenraad Debackere & Marc Luwel, 2003. "Science cited in patents: A geographic "flow" analysis of bibliographic citation patterns in patents," Scientometrics, Springer;Akadémiai Kiadó, vol. 58(2), pages 241-263, October.
    7. Mogoutov, Andrei & Kahane, Bernard, 2007. "Data search strategy for science and technology emergence: A scalable and evolutionary query for nanotechnology tracking," Research Policy, Elsevier, vol. 36(6), pages 893-903, July.
    Full references (including those not matched with items on IDEAS)

    Citations

    Citations are extracted by the CitEc Project, subscribe to its RSS feed for this item.
    as


    Cited by:

    1. Tomaz Bartol & Karmen Stopar, 2015. "Nano language and distribution of article title terms according to power laws," Scientometrics, Springer;Akadémiai Kiadó, vol. 103(2), pages 435-451, May.
    2. Edgar Schiebel & Marianne Hörlesberger & Ivana Roche & Claire François & Dominique Besagni, 2010. "An advanced diffusion model to identify emergent research issues: the case of optoelectronic devices," Scientometrics, Springer;Akadémiai Kiadó, vol. 83(3), pages 765-781, June.
    3. Patrick Wolf & Tobias Buchmann, 2021. "Analyzing development patterns in research networks and technology," Review of Evolutionary Political Economy, Springer, vol. 2(1), pages 55-81, April.
    4. Jordan A. Comins & Loet Leydesdorff, 2017. "Citation algorithms for identifying research milestones driving biomedical innovation," Scientometrics, Springer;Akadémiai Kiadó, vol. 110(3), pages 1495-1504, March.
    5. Leydesdorff, Loet & Welbers, Kasper, 2011. "The semantic mapping of words and co-words in contexts," Journal of Informetrics, Elsevier, vol. 5(3), pages 469-475.
    6. Gurney, Thomas & Horlings, Edwin & van den Besselaar, Peter & Sumikura, Koichi & Schoen, Antoine & Laurens, Patricia & Pardo, Daniel, 2014. "Analysing knowledge capture mechanisms: Methods and a stylised bioventure case," Journal of Informetrics, Elsevier, vol. 8(1), pages 259-272.
    7. Shin, Hyunjin & Woo, Hyun Goo & Sohn, Kyung-Ah & Lee, Sungjoo, 2023. "Comparing research trends with patenting activities in the biomedical sector: The case of dementia," Technological Forecasting and Social Change, Elsevier, vol. 195(C).

    Most related items

    These are the items that most often cite the same works as this one and are cited by the same works as this one.
    1. Arman Avadikyan & Gilles Lambert & Christophe Lerch, 2016. "A Multi-Level Perspective on Ambidexterity: The Case of a Synchrotron Research Facility," Working Papers of BETA 2016-44, Bureau d'Economie Théorique et Appliquée, UDS, Strasbourg.
    2. Habicht, Hagen & Oliveira, Pedro & Shcherbatiuk, Viktoriia, 2012. "User Innovators: When Patients Set Out to Help Themselves and End Up Helping Many," Die Unternehmung - Swiss Journal of Business Research and Practice, Nomos Verlagsgesellschaft mbH & Co. KG, vol. 66(3), pages 277-295.
    3. Pamela D. Morrison & John H. Roberts & Eric von Hippel, 2000. "Determinants of User Innovation and Innovation Sharing in a Local Market," Management Science, INFORMS, vol. 46(12), pages 1513-1527, December.
    4. Leonardo Costa Ribeiro & Glenda Kruss & Gustavo Britto & Américo Tristão Bernardes & Eduardo Motta e Albuquerque, 2014. "A methodology for unveiling global innovation networks: patent citations as clues to cross border knowledge flows," Scientometrics, Springer;Akadémiai Kiadó, vol. 101(1), pages 61-83, October.
    5. repec:wsi:acsxxx:v:21:y:2019:i:08:n:s1363919619500142 is not listed on IDEAS
    6. Nicolai J. Foss & Keld Laursen & Torben Pedersen, 2011. "Linking Customer Interaction and Innovation: The Mediating Role of New Organizational Practices," Organization Science, INFORMS, vol. 22(4), pages 980-999, August.
    7. Bosul Yoo & Sotaro Katsumata & Takeyasu Ichikohji, 2017. "The Impact of Customer Orientation on Quantity and Quality of User-Generated Content: A Multi-Country Case Study of Mobile Applications," Discussion Papers in Economics and Business 17-12, Osaka University, Graduate School of Economics.
    8. Matt, M. & Colinet, L. & Gaunand, A. & Joly, P.B., 2015. "A typology of impact pathways generated by a public agricultural research organization," Working Papers 2015-03, Grenoble Applied Economics Laboratory (GAEL).
    9. Alexander Brem & Volker Bilgram & Adele Gutstein, 2021. "Involving Lead Users in Innovation: A Structured Summary of Research on the Lead User Method," World Scientific Book Chapters, in: Alexander Brem (ed.), Emerging Issues and Trends in INNOVATION AND TECHNOLOGY MANAGEMENT, chapter 2, pages 21-48, World Scientific Publishing Co. Pte. Ltd..
    10. De Marchi, Valentina, 2012. "Environmental innovation and R&D cooperation: Empirical evidence from Spanish manufacturing firms," Research Policy, Elsevier, vol. 41(3), pages 614-623.
    11. Mariia Shkolnykova, 2021. "Who shapes plant biotechnology in Germany? Joint analysis of the evolution of co-authors’ and co-inventors’ networks," Review of Evolutionary Political Economy, Springer, vol. 2(1), pages 27-54, April.
    12. Simon Wiederhold, 2012. "The Role of Public Procurement in Innovation: Theory and Empirical Evidence," ifo Beiträge zur Wirtschaftsforschung, ifo Institute - Leibniz Institute for Economic Research at the University of Munich, number 43.
    13. Guijie Zhang & Yuqiang Feng & Guang Yu & Luning Liu & Yanqiqi Hao, 2017. "Analyzing the time delay between scientific research and technology patents based on the citation distribution model," Scientometrics, Springer;Akadémiai Kiadó, vol. 111(3), pages 1287-1306, June.
    14. Liliana Doganova, 2009. "Entrepreneurship as a process of collective exploration," Working Papers halshs-00431695, HAL.
    15. Zsolt Katona, 2015. "Democracy in product design: Consumer participation and differentiation strategies," Quantitative Marketing and Economics (QME), Springer, vol. 13(4), pages 359-394, December.
    16. Markus Ernst & Alexander Brem, 2017. "Social Media for Identifying Lead Users? Insights into Lead Users’ Social Media Habits," International Journal of Innovation and Technology Management (IJITM), World Scientific Publishing Co. Pte. Ltd., vol. 14(04), pages 1-21, August.
    17. Laura J. Kornish & Jeremy Hutchison‐Krupat, 2017. "Research on Idea Generation and Selection: Implications for Management of Technology," Production and Operations Management, Production and Operations Management Society, vol. 26(4), pages 633-651, April.
    18. Furrer, Olivier & Sudharshan, Devanathan & Tsiotsou, Rodoula H. & Liu, Ben S., 2016. "A framework for innovative service design," FSES Working Papers 476, Faculty of Economics and Social Sciences, University of Freiburg/Fribourg Switzerland.
    19. Schweisfurth, Tim G. & Dharmawan, Magha P., 2019. "Does lead userness foster idea implementation and diffusion? A study of internal shopfloor users," Research Policy, Elsevier, vol. 48(1), pages 289-297.
    20. Edler, Jakob & Georghiou, Luke, 2007. "Public procurement and innovation--Resurrecting the demand side," Research Policy, Elsevier, vol. 36(7), pages 949-963, September.
    21. Yan Qi & Xin Zhang & Zhengyin Hu & Bin Xiang & Ran Zhang & Shu Fang, 2022. "Choosing the right collaboration partner for innovation: a framework based on topic analysis and link prediction," Scientometrics, Springer;Akadémiai Kiadó, vol. 127(9), pages 5519-5550, September.

    Corrections

    All material on this site has been provided by the respective publishers and authors. You can help correct errors and omissions. When requesting a correction, please mention this item's handle: RePEc:eee:infome:v:2:y:2008:i:4:p:341-353. See general information about how to correct material in RePEc.

    If you have authored this item and are not yet registered with RePEc, we encourage you to do it here. This allows to link your profile to this item. It also allows you to accept potential citations to this item that we are uncertain about.

    If CitEc recognized a bibliographic reference but did not link an item in RePEc to it, you can help with this form .

    If you know of missing items citing this one, you can help us creating those links by adding the relevant references in the same way as above, for each refering item. If you are a registered author of this item, you may also want to check the "citations" tab in your RePEc Author Service profile, as there may be some citations waiting for confirmation.

    For technical questions regarding this item, or to correct its authors, title, abstract, bibliographic or download information, contact: Catherine Liu (email available below). General contact details of provider: http://www.elsevier.com/locate/joi .

    Please note that corrections may take a couple of weeks to filter through the various RePEc services.

    IDEAS is a RePEc service. RePEc uses bibliographic data supplied by the respective publishers.