IDEAS home Printed from https://ideas.repec.org/a/eee/csdana/v83y2015icp140-150.html
   My bibliography  Save this article

Regression analysis of bivariate current status data under the Gamma-frailty proportional hazards model using the EM algorithm

Author

Listed:
  • Wang, Naichen
  • Wang, Lianming
  • McMahan, Christopher S.

Abstract

The Gamma-frailty proportional hazards (PH) model is commonly used to analyze correlated survival data. Despite this model’s popularity, the analysis of correlated current status data under the Gamma-frailty PH model can prove to be challenging using traditional techniques. Consequently, in this paper we develop a novel expectation–maximization (EM) algorithm under the Gamma-frailty PH model to study bivariate current status data. Our method uses a monotone spline representation to approximate the unknown conditional cumulative baseline hazard functions. Proceeding in this fashion leads to the estimation of a finite number of parameters while simultaneously allowing for modeling flexibility. The derivation of the proposed EM algorithm relies on a three-stage data augmentation involving Poisson latent variables. The resulting algorithm is easy to implement, robust to initialization, and enjoys quick convergence. Simulation results suggest that the proposed method works well and is robust to the misspecification of the frailty distribution. Our methodology is used to analyze chlamydia and gonorrhea data collected by the Nebraska Public Health Laboratory as a part of the Infertility Prevention Project.

Suggested Citation

  • Wang, Naichen & Wang, Lianming & McMahan, Christopher S., 2015. "Regression analysis of bivariate current status data under the Gamma-frailty proportional hazards model using the EM algorithm," Computational Statistics & Data Analysis, Elsevier, vol. 83(C), pages 140-150.
    • Handle: RePEc:eee:csdana:v:83:y:2015:i:c:p:140-150
    DOI: 10.1016/j.csda.2014.10.013
    as

    Download full text from publisher

    File URL: http://www.sciencedirect.com/science/article/pii/S0167947314003053
    Download Restriction: Full text for ScienceDirect subscribers only.
    File URL: https://libkey.io/10.1016/j.csda.2014.10.013?utm_source=ideas
    LibKey link: if access is restricted and if your library uses this service, LibKey will redirect you to where you can use your library subscription to access this item
    ---><---

    As the access to this document is restricted, you may want to search for a different version of it.

    References listed on IDEAS

    as
    1. Cai, Bo & Lin, Xiaoyan & Wang, Lianming, 2011. "Bayesian proportional hazards model for current status data with monotone splines," Computational Statistics & Data Analysis, Elsevier, vol. 55(9), pages 2644-2651, September.
    2. Wen, Chi-Chung & Chen, Yi-Hau, 2011. "Nonparametric maximum likelihood analysis of clustered current status data with the gamma-frailty Cox model," Computational Statistics & Data Analysis, Elsevier, vol. 55(2), pages 1053-1060, February.
    3. Guosheng Yin & Joseph G. Ibrahim, 2005. "A Class of Bayesian Shared Gamma Frailty Models with Multivariate Failure Time Data," Biometrics, The International Biometric Society, vol. 61(1), pages 208-216, March.
    4. David B. Dunson & Gregg E. Dinse, 2002. "Bayesian Models for Multivariate Current Status Data with Informative Censoring," Biometrics, The International Biometric Society, vol. 58(1), pages 79-88, March.
    5. Wang, Lianming & Lin, Xiaoyan, 2011. "A Bayesian approach for analyzing case 2 interval-censored data under the semiparametric proportional odds model," Statistics & Probability Letters, Elsevier, vol. 81(7), pages 876-883, July.
    6. William B. Goggins & Dianne M. Finkelstein, 2000. "A Proportional Hazards Model for Multivariate Interval-Censored Failure Time Data," Biometrics, The International Biometric Society, vol. 56(3), pages 940-943, September.
    Full references (including those not matched with items on IDEAS)

    Citations

    Citations are extracted by the CitEc Project, subscribe to its RSS feed for this item.
    as


    Cited by:

    1. Xu, Yang & Zhao, Shishun & Hu, Tao & Sun, Jianguo, 2021. "Variable selection for generalized odds rate mixture cure models with interval-censored failure time data," Computational Statistics & Data Analysis, Elsevier, vol. 156(C).
    2. Hao Liu & Jing Qin, 2018. "Semiparametric probit models with univariate and bivariate current†status data," Biometrics, The International Biometric Society, vol. 74(1), pages 68-76, March.
    3. Gamage, Prabhashi W. Withana & McMahan, Christopher S. & Wang, Lianming & Tu, Wanzhu, 2018. "A Gamma-frailty proportional hazards model for bivariate interval-censored data," Computational Statistics & Data Analysis, Elsevier, vol. 128(C), pages 354-366.
    4. Qingning Zhou & Tao Hu & Jianguo Sun, 2017. "A Sieve Semiparametric Maximum Likelihood Approach for Regression Analysis of Bivariate Interval-Censored Failure Time Data," Journal of the American Statistical Association, Taylor & Francis Journals, vol. 112(518), pages 664-672, April.
    5. Petti, Danilo & Eletti, Alessia & Marra, Giampiero & Radice, Rosalba, 2022. "Copula link-based additive models for bivariate time-to-event outcomes with general censoring scheme," Computational Statistics & Data Analysis, Elsevier, vol. 175(C).
    6. González, M. & Minuesa, C. & del Puerto, I., 2016. "Maximum likelihood estimation and expectation–maximization algorithm for controlled branching processes," Computational Statistics & Data Analysis, Elsevier, vol. 93(C), pages 209-227.
    7. Prabhashi W. Withana Gamage & Monica Chaudari & Christopher S. McMahan & Edwin H. Kim & Michael R. Kosorok, 2020. "An extended proportional hazards model for interval-censored data subject to instantaneous failures," Lifetime Data Analysis: An International Journal Devoted to Statistical Methods and Applications for Time-to-Event Data, Springer, vol. 26(1), pages 158-182, January.
    8. Donglin Zeng & Fei Gao & D. Y. Lin, 2017. "Maximum likelihood estimation for semiparametric regression models with multivariate interval-censored data," Biometrika, Biometrika Trust, vol. 104(3), pages 505-525.
    9. Li, Shuwei & Hu, Tao & Wang, Peijie & Sun, Jianguo, 2017. "Regression analysis of current status data in the presence of dependent censoring with applications to tumorigenicity experiments," Computational Statistics & Data Analysis, Elsevier, vol. 110(C), pages 75-86.

    Most related items

    These are the items that most often cite the same works as this one and are cited by the same works as this one.
    1. Gamage, Prabhashi W. Withana & McMahan, Christopher S. & Wang, Lianming & Tu, Wanzhu, 2018. "A Gamma-frailty proportional hazards model for bivariate interval-censored data," Computational Statistics & Data Analysis, Elsevier, vol. 128(C), pages 354-366.
    2. Donglin Zeng & Fei Gao & D. Y. Lin, 2017. "Maximum likelihood estimation for semiparametric regression models with multivariate interval-censored data," Biometrika, Biometrika Trust, vol. 104(3), pages 505-525.
    3. Qingning Zhou & Tao Hu & Jianguo Sun, 2017. "A Sieve Semiparametric Maximum Likelihood Approach for Regression Analysis of Bivariate Interval-Censored Failure Time Data," Journal of the American Statistical Association, Taylor & Francis Journals, vol. 112(518), pages 664-672, April.
    4. Hao Liu & Jing Qin, 2018. "Semiparametric probit models with univariate and bivariate current†status data," Biometrics, The International Biometric Society, vol. 74(1), pages 68-76, March.
    5. Lianming Wang & David B. Dunson, 2010. "Semiparametric Bayes Multiple Testing: Applications to Tumor Data," Biometrics, The International Biometric Society, vol. 66(2), pages 493-501, June.
    6. Ying Zhang & Lei Hua & Jian Huang, 2010. "A Spline‐Based Semiparametric Maximum Likelihood Estimation Method for the Cox Model with Interval‐Censored Data," Scandinavian Journal of Statistics, Danish Society for Theoretical Statistics;Finnish Statistical Society;Norwegian Statistical Association;Swedish Statistical Association, vol. 37(2), pages 338-354, June.
    7. Ying Hung & Li‐Hsiang Lin & C. F. Jeff Wu, 2022. "Varying coefficient frailty models with applications in single molecular experiments," Biometrics, The International Biometric Society, vol. 78(2), pages 474-486, June.
    8. Chen, Ling & Sun, Jianguo, 2010. "A multiple imputation approach to the analysis of interval-censored failure time data with the additive hazards model," Computational Statistics & Data Analysis, Elsevier, vol. 54(4), pages 1109-1116, April.
    9. Sedigheh Mirzaei Salehabadi & Debasis Sengupta & Rituparna Das, 2015. "Parametric Estimation of Menarcheal Age Distribution Based on Recall Data," Scandinavian Journal of Statistics, Danish Society for Theoretical Statistics;Finnish Statistical Society;Norwegian Statistical Association;Swedish Statistical Association, vol. 42(1), pages 290-305, March.
    10. Prabhashi W. Withana Gamage & Christopher S. McMahan & Lianming Wang, 2023. "A flexible parametric approach for analyzing arbitrarily censored data that are potentially subject to left truncation under the proportional hazards model," Lifetime Data Analysis: An International Journal Devoted to Statistical Methods and Applications for Time-to-Event Data, Springer, vol. 29(1), pages 188-212, January.
    11. Du, Mingyue & Li, Huiqiong & Sun, Jianguo, 2021. "Regression analysis of censored data with nonignorable missing covariates and application to Alzheimer Disease," Computational Statistics & Data Analysis, Elsevier, vol. 157(C).
    12. Yichen Lou & Peijie Wang & Jianguo Sun, 2023. "A semi-parametric weighted likelihood approach for regression analysis of bivariate interval-censored outcomes from case-cohort studies," Lifetime Data Analysis: An International Journal Devoted to Statistical Methods and Applications for Time-to-Event Data, Springer, vol. 29(3), pages 628-653, July.
    13. Minggen Lu & Christopher S. McMahan, 2018. "A partially linear proportional hazards model for current status data," Biometrics, The International Biometric Society, vol. 74(4), pages 1240-1249, December.
    14. David B. Dunson & Gregg E. Dinse, 2002. "Bayesian Models for Multivariate Current Status Data with Informative Censoring," Biometrics, The International Biometric Society, vol. 58(1), pages 79-88, March.
    15. Mengzhu Yu & Mingyue Du, 2022. "Regression Analysis of Multivariate Interval-Censored Failure Time Data under Transformation Model with Informative Censoring," Mathematics, MDPI, vol. 10(18), pages 1-17, September.
    16. Chunling Wang & Xiaoyan Lin, 2022. "Bayesian Semiparametric Regression Analysis of Multivariate Panel Count Data," Stats, MDPI, vol. 5(2), pages 1-17, May.
    17. Guosheng Yin & Joseph G. Ibrahim, 2005. "A General Class of Bayesian Survival Models with Zero and Nonzero Cure Fractions," Biometrics, The International Biometric Society, vol. 61(2), pages 403-412, June.
    18. Xiaoming Lu & Zhaozhi Fan, 2015. "Weighted quantile regression for longitudinal data," Computational Statistics, Springer, vol. 30(2), pages 569-592, June.
    19. Baihua He & Yanyan Liu & Yuanshan Wu & Xingqiu Zhao, 2020. "Semiparametric efficient estimation for additive hazards regression with case II interval-censored survival data," Lifetime Data Analysis: An International Journal Devoted to Statistical Methods and Applications for Time-to-Event Data, Springer, vol. 26(4), pages 708-730, October.
    20. Jialiang Li & Tonghui Yu & Jing Lv & Mei‐Ling Ting Lee, 2021. "Semiparametric model averaging prediction for lifetime data via hazards regression," Journal of the Royal Statistical Society Series C, Royal Statistical Society, vol. 70(5), pages 1187-1209, November.

    Corrections

    All material on this site has been provided by the respective publishers and authors. You can help correct errors and omissions. When requesting a correction, please mention this item's handle: RePEc:eee:csdana:v:83:y:2015:i:c:p:140-150. See general information about how to correct material in RePEc.

    If you have authored this item and are not yet registered with RePEc, we encourage you to do it here. This allows to link your profile to this item. It also allows you to accept potential citations to this item that we are uncertain about.

    If CitEc recognized a bibliographic reference but did not link an item in RePEc to it, you can help with this form .

    If you know of missing items citing this one, you can help us creating those links by adding the relevant references in the same way as above, for each refering item. If you are a registered author of this item, you may also want to check the "citations" tab in your RePEc Author Service profile, as there may be some citations waiting for confirmation.

    For technical questions regarding this item, or to correct its authors, title, abstract, bibliographic or download information, contact: Catherine Liu (email available below). General contact details of provider: http://www.elsevier.com/locate/csda .

    Please note that corrections may take a couple of weeks to filter through the various RePEc services.

    IDEAS is a RePEc service. RePEc uses bibliographic data supplied by the respective publishers.