IDEAS home Printed from https://ideas.repec.org/a/eee/csdana/v125y2018icp44-56.html
   My bibliography  Save this article

Unsupervised learning of mixture regression models for longitudinal data

Author

Listed:
  • Xu, Peirong
  • Peng, Heng
  • Huang, Tao

Abstract

This paper is concerned with learning of mixture regression models for individuals that are measured repeatedly. The adjective “unsupervised” implies that the number of mixing components is unknown and has to be determined, ideally by data driven tools. For this purpose, a novel penalized method is proposed to simultaneously select the number of mixing components and to estimate the mixture proportions and unknown parameters in the models. The proposed method is capable of handling both continuous and discrete responses by only requiring the first two moment conditions of the model distribution. It is shown to be consistent in both selecting the number of components and estimating the mixture proportions and unknown regression parameters. Further, a modified EM algorithm is developed to seamlessly integrate model selection and estimation. Simulation studies are conducted to evaluate the finite sample performance of the proposed procedure. And it is further illustrated via an analysis of a primary biliary cirrhosis data set.

Suggested Citation

  • Xu, Peirong & Peng, Heng & Huang, Tao, 2018. "Unsupervised learning of mixture regression models for longitudinal data," Computational Statistics & Data Analysis, Elsevier, vol. 125(C), pages 44-56.
  • Handle: RePEc:eee:csdana:v:125:y:2018:i:c:p:44-56
    DOI: 10.1016/j.csda.2018.03.012
    as

    Download full text from publisher

    File URL: http://www.sciencedirect.com/science/article/pii/S0167947318300720
    Download Restriction: Full text for ScienceDirect subscribers only.

    File URL: https://libkey.io/10.1016/j.csda.2018.03.012?utm_source=ideas
    LibKey link: if access is restricted and if your library uses this service, LibKey will redirect you to where you can use your library subscription to access this item
    ---><---

    As the access to this document is restricted, you may want to search for a different version of it.

    References listed on IDEAS

    as
    1. Jianhua Z. Huang & Liangyue Zhang & Lan Zhou, 2007. "Efficient Estimation in Marginal Partially Linear Models for Longitudinal/Clustered Data Using Splines," Scandinavian Journal of Statistics, Danish Society for Theoretical Statistics;Finnish Statistical Society;Norwegian Statistical Association;Swedish Statistical Association, vol. 34(3), pages 451-477, September.
    2. Christophe Genolini & Bruno Falissard, 2010. "KmL: k-means for longitudinal data," Computational Statistics, Springer, vol. 25(2), pages 317-328, June.
    3. Fan J. & Li R., 2001. "Variable Selection via Nonconcave Penalized Likelihood and its Oracle Properties," Journal of the American Statistical Association, American Statistical Association, vol. 96, pages 1348-1360, December.
    4. Chen, Jiahua & Khalili, Abbas, 2008. "Order Selection in Finite Mixture Models With a Nonsmooth Penalty," Journal of the American Statistical Association, American Statistical Association, vol. 103(484), pages 1674-1683.
    5. Antonello Maruotti, 2011. "Mixed Hidden Markov Models for Longitudinal Data: An Overview," International Statistical Review, International Statistical Institute, vol. 79(3), pages 427-454, December.
    6. Peirong Xu & Jun Zhang & Xingfang Huang & Tao Wang, 2016. "Efficient estimation for marginal generalized partially linear single-index models with longitudinal data," TEST: An Official Journal of the Spanish Society of Statistics and Operations Research, Springer;Sociedad de Estadística e Investigación Operativa, vol. 25(3), pages 413-431, September.
    7. De la Cruz-Mesia, Rolando & Quintana, Fernando A. & Marshall, Guillermo, 2008. "Model-based clustering for longitudinal data," Computational Statistics & Data Analysis, Elsevier, vol. 52(3), pages 1441-1457, January.
    8. Wang, Xianlong & Qu, Annie, 2014. "Efficient classification for longitudinal data," Computational Statistics & Data Analysis, Elsevier, vol. 78(C), pages 119-134.
    9. Komárek, Arnost & Lesaffre, Emmanuel, 2008. "Generalized linear mixed model with a penalized Gaussian mixture as a random effects distribution," Computational Statistics & Data Analysis, Elsevier, vol. 52(7), pages 3441-3458, March.
    10. Xu, Peirong & Zhu, Lixing, 2012. "Estimation for a marginal generalized single-index longitudinal model," Journal of Multivariate Analysis, Elsevier, vol. 105(1), pages 285-299.
    11. James G. Booth & George Casella & James P. Hobert, 2008. "Clustering using objective functions and stochastic search," Journal of the Royal Statistical Society Series B, Royal Statistical Society, vol. 70(1), pages 119-139, February.
    12. Hansheng Wang & Runze Li & Chih-Ling Tsai, 2007. "Tuning parameter selectors for the smoothly clipped absolute deviation method," Biometrika, Biometrika Trust, vol. 94(3), pages 553-568.
    Full references (including those not matched with items on IDEAS)

    Citations

    Citations are extracted by the CitEc Project, subscribe to its RSS feed for this item.
    as


    Cited by:

    1. Pei, Youquan & Peng, Heng & Xu, Jinfeng, 2024. "A latent class Cox model for heterogeneous time-to-event data," Journal of Econometrics, Elsevier, vol. 239(2).

    Most related items

    These are the items that most often cite the same works as this one and are cited by the same works as this one.
    1. Wan-Lun Wang, 2019. "Mixture of multivariate t nonlinear mixed models for multiple longitudinal data with heterogeneity and missing values," TEST: An Official Journal of the Spanish Society of Statistics and Operations Research, Springer;Sociedad de Estadística e Investigación Operativa, vol. 28(1), pages 196-222, March.
    2. Ping Zeng & Yongyue Wei & Yang Zhao & Jin Liu & Liya Liu & Ruyang Zhang & Jianwei Gou & Shuiping Huang & Feng Chen, 2014. "Variable selection approach for zero-inflated count data via adaptive lasso," Journal of Applied Statistics, Taylor & Francis Journals, vol. 41(4), pages 879-894, April.
    3. Zhou, Jie & Song, Xinyuan & Sun, Liuquan, 2020. "Continuous time hidden Markov model for longitudinal data," Journal of Multivariate Analysis, Elsevier, vol. 179(C).
    4. Shuang Zhang & Xingdong Feng, 2022. "Distributed identification of heterogeneous treatment effects," Computational Statistics, Springer, vol. 37(1), pages 57-89, March.
    5. Jun Zhu & Hsin‐Cheng Huang & Perla E. Reyes, 2010. "On selection of spatial linear models for lattice data," Journal of the Royal Statistical Society Series B, Royal Statistical Society, vol. 72(3), pages 389-402, June.
    6. Ye, Mao & Lu, Zhao-Hua & Li, Yimei & Song, Xinyuan, 2019. "Finite mixture of varying coefficient model: Estimation and component selection," Journal of Multivariate Analysis, Elsevier, vol. 171(C), pages 452-474.
    7. Kangning Wang & Lu Lin, 2017. "Robust and efficient direction identification for groupwise additive multiple-index models and its applications," TEST: An Official Journal of the Spanish Society of Statistics and Operations Research, Springer;Sociedad de Estadística e Investigación Operativa, vol. 26(1), pages 22-45, March.
    8. Xia Chen & Liyue Mao, 2020. "Penalized empirical likelihood for partially linear errors-in-variables models," AStA Advances in Statistical Analysis, Springer;German Statistical Society, vol. 104(4), pages 597-623, December.
    9. Tizheng Li & Xiaojuan Kang, 2022. "Variable selection of higher-order partially linear spatial autoregressive model with a diverging number of parameters," Statistical Papers, Springer, vol. 63(1), pages 243-285, February.
    10. Fei Jin & Lung-fei Lee, 2018. "Lasso Maximum Likelihood Estimation of Parametric Models with Singular Information Matrices," Econometrics, MDPI, vol. 6(1), pages 1-24, February.
    11. Xinyang Wang & Dehui Wang & Kai Yang, 2021. "Integer-valued time series model order shrinkage and selection via penalized quasi-likelihood approach," Metrika: International Journal for Theoretical and Applied Statistics, Springer, vol. 84(5), pages 713-750, July.
    12. Yongjin Li & Qingzhao Zhang & Qihua Wang, 2017. "Penalized estimation equation for an extended single-index model," Annals of the Institute of Statistical Mathematics, Springer;The Institute of Statistical Mathematics, vol. 69(1), pages 169-187, February.
    13. Guang Cheng & Hao Zhang & Zuofeng Shang, 2015. "Sparse and efficient estimation for partial spline models with increasing dimension," Annals of the Institute of Statistical Mathematics, Springer;The Institute of Statistical Mathematics, vol. 67(1), pages 93-127, February.
    14. Sakyajit Bhattacharya & Paul McNicholas, 2014. "A LASSO-penalized BIC for mixture model selection," Advances in Data Analysis and Classification, Springer;German Classification Society - Gesellschaft für Klassifikation (GfKl);Japanese Classification Society (JCS);Classification and Data Analysis Group of the Italian Statistical Society (CLADAG);International Federation of Classification Societies (IFCS), vol. 8(1), pages 45-61, March.
    15. Atefeh Zarei & Zahra Khodadadi & Mohsen Maleki & Karim Zare, 2023. "Robust mixture regression modeling based on two-piece scale mixtures of normal distributions," Advances in Data Analysis and Classification, Springer;German Classification Society - Gesellschaft für Klassifikation (GfKl);Japanese Classification Society (JCS);Classification and Data Analysis Group of the Italian Statistical Society (CLADAG);International Federation of Classification Societies (IFCS), vol. 17(1), pages 181-210, March.
    16. Ramon I. Garcia & Joseph G. Ibrahim & Hongtu Zhu, 2010. "Variable Selection in the Cox Regression Model with Covariates Missing at Random," Biometrics, The International Biometric Society, vol. 66(1), pages 97-104, March.
    17. Dengke Xu & Zhongzhan Zhang & Liucang Wu, 2014. "Variable selection in high-dimensional double generalized linear models," Statistical Papers, Springer, vol. 55(2), pages 327-347, May.
    18. Bian, Yuan & Yi, Grace Y. & He, Wenqing, 2024. "A unified framework of analyzing missing data and variable selection using regularized likelihood," Computational Statistics & Data Analysis, Elsevier, vol. 194(C).
    19. Ngai Hang Chan & Linhao Gao & Wilfredo Palma, 2022. "Simultaneous variable selection and structural identification for time‐varying coefficient models," Journal of Time Series Analysis, Wiley Blackwell, vol. 43(4), pages 511-531, July.
    20. Qingliang Fan & Yaqian Wu, 2020. "Endogenous Treatment Effect Estimation with some Invalid and Irrelevant Instruments," Papers 2006.14998, arXiv.org.

    Corrections

    All material on this site has been provided by the respective publishers and authors. You can help correct errors and omissions. When requesting a correction, please mention this item's handle: RePEc:eee:csdana:v:125:y:2018:i:c:p:44-56. See general information about how to correct material in RePEc.

    If you have authored this item and are not yet registered with RePEc, we encourage you to do it here. This allows to link your profile to this item. It also allows you to accept potential citations to this item that we are uncertain about.

    If CitEc recognized a bibliographic reference but did not link an item in RePEc to it, you can help with this form .

    If you know of missing items citing this one, you can help us creating those links by adding the relevant references in the same way as above, for each refering item. If you are a registered author of this item, you may also want to check the "citations" tab in your RePEc Author Service profile, as there may be some citations waiting for confirmation.

    For technical questions regarding this item, or to correct its authors, title, abstract, bibliographic or download information, contact: Catherine Liu (email available below). General contact details of provider: http://www.elsevier.com/locate/csda .

    Please note that corrections may take a couple of weeks to filter through the various RePEc services.

    IDEAS is a RePEc service. RePEc uses bibliographic data supplied by the respective publishers.