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Unsupervised learning of mixture regression models for longitudinal data

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  • Xu, Peirong
  • Peng, Heng
  • Huang, Tao

Abstract

This paper is concerned with learning of mixture regression models for individuals that are measured repeatedly. The adjective “unsupervised” implies that the number of mixing components is unknown and has to be determined, ideally by data driven tools. For this purpose, a novel penalized method is proposed to simultaneously select the number of mixing components and to estimate the mixture proportions and unknown parameters in the models. The proposed method is capable of handling both continuous and discrete responses by only requiring the first two moment conditions of the model distribution. It is shown to be consistent in both selecting the number of components and estimating the mixture proportions and unknown regression parameters. Further, a modified EM algorithm is developed to seamlessly integrate model selection and estimation. Simulation studies are conducted to evaluate the finite sample performance of the proposed procedure. And it is further illustrated via an analysis of a primary biliary cirrhosis data set.

Suggested Citation

  • Xu, Peirong & Peng, Heng & Huang, Tao, 2018. "Unsupervised learning of mixture regression models for longitudinal data," Computational Statistics & Data Analysis, Elsevier, vol. 125(C), pages 44-56.
  • Handle: RePEc:eee:csdana:v:125:y:2018:i:c:p:44-56
    DOI: 10.1016/j.csda.2018.03.012
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    References listed on IDEAS

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    1. Antonello Maruotti, 2011. "Mixed Hidden Markov Models for Longitudinal Data: An Overview," International Statistical Review, International Statistical Institute, vol. 79(3), pages 427-454, December.
    2. Peirong Xu & Jun Zhang & Xingfang Huang & Tao Wang, 2016. "Efficient estimation for marginal generalized partially linear single-index models with longitudinal data," TEST: An Official Journal of the Spanish Society of Statistics and Operations Research, Springer;Sociedad de Estadística e Investigación Operativa, vol. 25(3), pages 413-431, September.
    3. De la Cruz-Mesia, Rolando & Quintana, Fernando A. & Marshall, Guillermo, 2008. "Model-based clustering for longitudinal data," Computational Statistics & Data Analysis, Elsevier, vol. 52(3), pages 1441-1457, January.
    4. Wang, Xianlong & Qu, Annie, 2014. "Efficient classification for longitudinal data," Computational Statistics & Data Analysis, Elsevier, vol. 78(C), pages 119-134.
    5. Komárek, Arnost & Lesaffre, Emmanuel, 2008. "Generalized linear mixed model with a penalized Gaussian mixture as a random effects distribution," Computational Statistics & Data Analysis, Elsevier, vol. 52(7), pages 3441-3458, March.
    6. Xu, Peirong & Zhu, Lixing, 2012. "Estimation for a marginal generalized single-index longitudinal model," Journal of Multivariate Analysis, Elsevier, vol. 105(1), pages 285-299.
    7. Jianhua Z. Huang & Liangyue Zhang & Lan Zhou, 2007. "Efficient Estimation in Marginal Partially Linear Models for Longitudinal/Clustered Data Using Splines," Scandinavian Journal of Statistics, Danish Society for Theoretical Statistics;Finnish Statistical Society;Norwegian Statistical Association;Swedish Statistical Association, vol. 34(3), pages 451-477, September.
    8. Christophe Genolini & Bruno Falissard, 2010. "KmL: k-means for longitudinal data," Computational Statistics, Springer, vol. 25(2), pages 317-328, June.
    9. Fan J. & Li R., 2001. "Variable Selection via Nonconcave Penalized Likelihood and its Oracle Properties," Journal of the American Statistical Association, American Statistical Association, vol. 96, pages 1348-1360, December.
    10. James G. Booth & George Casella & James P. Hobert, 2008. "Clustering using objective functions and stochastic search," Journal of the Royal Statistical Society Series B, Royal Statistical Society, vol. 70(1), pages 119-139, February.
    11. Hansheng Wang & Runze Li & Chih-Ling Tsai, 2007. "Tuning parameter selectors for the smoothly clipped absolute deviation method," Biometrika, Biometrika Trust, vol. 94(3), pages 553-568.
    12. Chen, Jiahua & Khalili, Abbas, 2008. "Order Selection in Finite Mixture Models With a Nonsmooth Penalty," Journal of the American Statistical Association, American Statistical Association, vol. 103(484), pages 1674-1683.
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    Cited by:

    1. Pei, Youquan & Peng, Heng & Xu, Jinfeng, 2024. "A latent class Cox model for heterogeneous time-to-event data," Journal of Econometrics, Elsevier, vol. 239(2).

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