IDEAS home Printed from https://ideas.repec.org/a/bla/biomet/v71y2015i3p782-791.html
   My bibliography  Save this article

Penalized regression for interval‐censored times of disease progression: Selection of HLA markers in psoriatic arthritis

Author

Listed:
  • Ying Wu
  • Richard J. Cook

Abstract

Times of disease progression are interval‐censored when progression status is only known at a series of assessment times. This situation arises routinely in clinical trials and cohort studies when events of interest are only detectable upon imaging, based on blood tests, or upon careful clinical examination. We consider the problem of selecting important prognostic biomarkers from a large set of candidates when disease progression status is only known at irregularly spaced and individual‐specific assessment times. Penalized regression techniques (e.g., LASSO, adaptive LASSO, and SCAD) are adapted to handle interval‐censored time of disease progression. An expectation–maximization algorithm is described which is empirically shown to perform well. Application to the motivating study of the development of arthritis mutilans in patients with psoriatic arthritis is given and several important human leukocyte antigen (HLA) variables are identified for further investigation.

Suggested Citation

  • Ying Wu & Richard J. Cook, 2015. "Penalized regression for interval‐censored times of disease progression: Selection of HLA markers in psoriatic arthritis," Biometrics, The International Biometric Society, vol. 71(3), pages 782-791, September.
    • Handle: RePEc:bla:biomet:v:71:y:2015:i:3:p:782-791
    DOI: 10.1111/biom.12302
    as

    Download full text from publisher

    File URL: https://doi.org/10.1111/biom.12302
    Download Restriction: no
    File URL: https://libkey.io/10.1111/biom.12302?utm_source=ideas
    LibKey link: if access is restricted and if your library uses this service, LibKey will redirect you to where you can use your library subscription to access this item
    ---><---

    References listed on IDEAS

    as
    1. Zou, Hui, 2006. "The Adaptive Lasso and Its Oracle Properties," Journal of the American Statistical Association, American Statistical Association, vol. 101, pages 1418-1429, December.
    2. Tianxi Cai & Rebecca A. Betensky, 2003. "Hazard Regression for Interval-Censored Data with Penalized Spline," Biometrics, The International Biometric Society, vol. 59(3), pages 570-579, September.
    3. Hui Zou & Trevor Hastie, 2005. "Addendum: Regularization and variable selection via the elastic net," Journal of the Royal Statistical Society Series B, Royal Statistical Society, vol. 67(5), pages 768-768, November.
    4. Hui Zou & Trevor Hastie, 2005. "Regularization and variable selection via the elastic net," Journal of the Royal Statistical Society Series B, Royal Statistical Society, vol. 67(2), pages 301-320, April.
    5. Fan J. & Li R., 2001. "Variable Selection via Nonconcave Penalized Likelihood and its Oracle Properties," Journal of the American Statistical Association, American Statistical Association, vol. 96, pages 1348-1360, December.
    Full references (including those not matched with items on IDEAS)

    Citations

    Citations are extracted by the CitEc Project, subscribe to its RSS feed for this item.
    as


    Cited by:

    1. Ying Wu & Richard J. Cook, 2018. "Variable selection and prediction in biased samples with censored outcomes," Lifetime Data Analysis: An International Journal Devoted to Statistical Methods and Applications for Time-to-Event Data, Springer, vol. 24(1), pages 72-93, January.
    2. Xu, Yang & Zhao, Shishun & Hu, Tao & Sun, Jianguo, 2021. "Variable selection for generalized odds rate mixture cure models with interval-censored failure time data," Computational Statistics & Data Analysis, Elsevier, vol. 156(C).
    3. Du, Mingyue & Zhao, Xingqiu & Sun, Jianguo, 2022. "Variable selection for case-cohort studies with informatively interval-censored outcomes," Computational Statistics & Data Analysis, Elsevier, vol. 172(C).
    4. Du, Mingyue & Zhao, Xingqiu, 2024. "A conditional approach for regression analysis of case K interval-censored failure time data with informative censoring," Computational Statistics & Data Analysis, Elsevier, vol. 198(C).
    5. Fengting Yi & Niansheng Tang & Jianguo Sun, 2022. "Simultaneous variable selection and estimation for joint models of longitudinal and failure time data with interval censoring," Biometrics, The International Biometric Society, vol. 78(1), pages 151-164, March.

    Most related items

    These are the items that most often cite the same works as this one and are cited by the same works as this one.
    1. Tutz, Gerhard & Pößnecker, Wolfgang & Uhlmann, Lorenz, 2015. "Variable selection in general multinomial logit models," Computational Statistics & Data Analysis, Elsevier, vol. 82(C), pages 207-222.
    2. Margherita Giuzio, 2017. "Genetic algorithm versus classical methods in sparse index tracking," Decisions in Economics and Finance, Springer;Associazione per la Matematica, vol. 40(1), pages 243-256, November.
    3. Diego Vidaurre & Concha Bielza & Pedro Larrañaga, 2013. "A Survey of L1 Regression," International Statistical Review, International Statistical Institute, vol. 81(3), pages 361-387, December.
    4. Sheng, Ying & Wang, Qihua, 2019. "Simultaneous variable selection and class fusion with penalized distance criterion based classifiers," Computational Statistics & Data Analysis, Elsevier, vol. 133(C), pages 138-152.
    5. Yize Zhao & Matthias Chung & Brent A. Johnson & Carlos S. Moreno & Qi Long, 2016. "Hierarchical Feature Selection Incorporating Known and Novel Biological Information: Identifying Genomic Features Related to Prostate Cancer Recurrence," Journal of the American Statistical Association, Taylor & Francis Journals, vol. 111(516), pages 1427-1439, October.
    6. Amélie Charles & Olivier Darné, 2022. "Backcasting world trade growth using data reduction methods," The World Economy, Wiley Blackwell, vol. 45(10), pages 3169-3191, October.
    7. Gareth M. James & Peter Radchenko & Jinchi Lv, 2009. "DASSO: connections between the Dantzig selector and lasso," Journal of the Royal Statistical Society Series B, Royal Statistical Society, vol. 71(1), pages 127-142, January.
    8. Härdle, Wolfgang Karl & Chen, Shi & Liang, Chong & Schienle, Melanie, 2018. "Time-varying Limit Order Book Networks," IRTG 1792 Discussion Papers 2018-016, Humboldt University of Berlin, International Research Training Group 1792 "High Dimensional Nonstationary Time Series".
    9. Mike K. P. So & Wing Ki Liu & Amanda M. Y. Chu, 2018. "Bayesian Shrinkage Estimation Of Time-Varying Covariance Matrices In Financial Time Series," Advances in Decision Sciences, Asia University, Taiwan, vol. 22(1), pages 369-404, December.
    10. Wenning Feng & Abdhi Sarkar & Chae Young Lim & Tapabrata Maiti, 2016. "Variable selection for binary spatial regression: Penalized quasi‐likelihood approach," Biometrics, The International Biometric Society, vol. 72(4), pages 1164-1172, December.
    11. Umberto Amato & Anestis Antoniadis & Italia De Feis & Irene Gijbels, 2021. "Penalised robust estimators for sparse and high-dimensional linear models," Statistical Methods & Applications, Springer;Società Italiana di Statistica, vol. 30(1), pages 1-48, March.
    12. Camila Epprecht & Dominique Guegan & Álvaro Veiga & Joel Correa da Rosa, 2017. "Variable selection and forecasting via automated methods for linear models: LASSO/adaLASSO and Autometrics," Post-Print halshs-00917797, HAL.
    13. Wang, Christina Dan & Chen, Zhao & Lian, Yimin & Chen, Min, 2022. "Asset selection based on high frequency Sharpe ratio," Journal of Econometrics, Elsevier, vol. 227(1), pages 168-188.
    14. Bartosz Uniejewski, 2024. "Regularization for electricity price forecasting," Operations Research and Decisions, Wroclaw University of Science and Technology, Faculty of Management, vol. 34(3), pages 267-286.
    15. Peter Bühlmann & Jacopo Mandozzi, 2014. "High-dimensional variable screening and bias in subsequent inference, with an empirical comparison," Computational Statistics, Springer, vol. 29(3), pages 407-430, June.
    16. Peter Martey Addo & Dominique Guegan & Bertrand Hassani, 2018. "Credit Risk Analysis Using Machine and Deep Learning Models," Risks, MDPI, vol. 6(2), pages 1-20, April.
    17. Capanu, Marinela & Giurcanu, Mihai & Begg, Colin B. & Gönen, Mithat, 2023. "Subsampling based variable selection for generalized linear models," Computational Statistics & Data Analysis, Elsevier, vol. 184(C).
    18. Weng, Jiaying, 2022. "Fourier transform sparse inverse regression estimators for sufficient variable selection," Computational Statistics & Data Analysis, Elsevier, vol. 168(C).
    19. Matsui, Hidetoshi, 2014. "Variable and boundary selection for functional data via multiclass logistic regression modeling," Computational Statistics & Data Analysis, Elsevier, vol. 78(C), pages 176-185.
    20. Ander Wilson & Brian J. Reich, 2014. "Confounder selection via penalized credible regions," Biometrics, The International Biometric Society, vol. 70(4), pages 852-861, December.

    More about this item

    Statistics

    Access and download statistics

    Corrections

    All material on this site has been provided by the respective publishers and authors. You can help correct errors and omissions. When requesting a correction, please mention this item's handle: RePEc:bla:biomet:v:71:y:2015:i:3:p:782-791. See general information about how to correct material in RePEc.

    If you have authored this item and are not yet registered with RePEc, we encourage you to do it here. This allows to link your profile to this item. It also allows you to accept potential citations to this item that we are uncertain about.

    If CitEc recognized a bibliographic reference but did not link an item in RePEc to it, you can help with this form .

    If you know of missing items citing this one, you can help us creating those links by adding the relevant references in the same way as above, for each refering item. If you are a registered author of this item, you may also want to check the "citations" tab in your RePEc Author Service profile, as there may be some citations waiting for confirmation.

    For technical questions regarding this item, or to correct its authors, title, abstract, bibliographic or download information, contact: Wiley Content Delivery (email available below). General contact details of provider: http://www.blackwellpublishing.com/journal.asp?ref=0006-341X .

    Please note that corrections may take a couple of weeks to filter through the various RePEc services.

    IDEAS is a RePEc service. RePEc uses bibliographic data supplied by the respective publishers.