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Music and Biomarkers of Stress: A Systematic Review

Author

Listed:
  • Michael W. Ishak

    (Cedars-Sinai Medical Center, Los Angeles, CA, USA)

  • Nathalie Herrera

    (Cedars-Sinai Medical Center, Los Angeles, CA, USA)

  • Alicia Halbert

    (Cedars-Sinai Medical Center, Los Angeles, CA, USA)

  • Jiaobing Tu

    (California Institute of Technology, Pasadena, CA, USA)

  • Wei Gao

    (California Institute of Technology, Pasadena, CA, USA)

Abstract

Objective: The purpose of this paper is to review literature on music and biomarkers of stress in order to (1) Identify music interventions and (2) Detail the biomarkers of stress associated with music. Methods: PRISMA guidelines were followed in performing this systematic review. Studies published from January 1995 to January 2020 that pertain to biomarkers of stress and music were identified through the use of the PubMed database, using the keywords: ‘music’ AND ‘biomarker’ OR ‘marker’ OR ‘hormone’. Two authors independently conducted a focused analysis and reached a final consensus on 16 studies that met the specific selection criteria and passed the study quality checks. Results: The reviewed studies were all randomized controlled trials. Reviewed music interventions included Music Listening (ML), Meditational Music (MM), ‘Guided Imagery and Music’ (GIM), and Singing. The studies showed that music is associated with a decreasing trend in cortisol, salivary ?-amylase, heart rate, and blood pressure, as well as an increasing trend in Immunoglobulin A (IgA), oxytocin, and EEG theta wave, while testosterone was associated with sex-related differences. Conclusion: Music is associated with significant changes in biomarkers of stress, suggesting that it could be utilized for the development of stress reduction tools.

Suggested Citation

  • Michael W. Ishak & Nathalie Herrera & Alicia Halbert & Jiaobing Tu & Wei Gao, 2020. "Music and Biomarkers of Stress: A Systematic Review," International Journal of Healthcare and Medical Sciences, Academic Research Publishing Group, vol. 6(5), pages 82-92, 10-2020.
    • Handle: RePEc:arp:ijohms:2020:p:82-92
    DOI: 10.32861/ijhms.65.82.92
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    References listed on IDEAS

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    1. Bruno Gingras & Gerald Pohler & W Tecumseh Fitch, 2014. "Exploring Shamanic Journeying: Repetitive Drumming with Shamanic Instructions Induces Specific Subjective Experiences but No Larger Cortisol Decrease than Instrumental Meditation Music," PLOS ONE, Public Library of Science, vol. 9(7), pages 1-9, July.
    2. David Moher & Alessandro Liberati & Jennifer Tetzlaff & Douglas G Altman & The PRISMA Group, 2009. "Preferred Reporting Items for Systematic Reviews and Meta-Analyses: The PRISMA Statement," PLOS Medicine, Public Library of Science, vol. 6(7), pages 1-6, July.
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