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Nampt: Intracellular and Extracellular Influence on Diabetes and Obesity

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  • Kevin G Culligan

    (Royal College of Surgeons in Ireland, Bahrain)

Abstract

The prevalence of Type 2 Diabetes Mellitus (T2DM) as a result of increased Obesity, or disability is increasing rapidly. However, only a relatively small percentage of obese individuals develop T2DM, suggesting the contribution of additional factors to whole body insulin resistance. Pharmacological intervention with several anti-diabetic agents, such as Thiazolidinediones (TZDs) can cause increased weight gain, but remain the only option for the majority of obese individuals.

Suggested Citation

  • Kevin G Culligan, 2017. "Nampt: Intracellular and Extracellular Influence on Diabetes and Obesity," Current Research in Diabetes & Obesity Journal, Juniper Publishers Inc., vol. 4(3), pages 62-66, October.
    • Handle: RePEc:adp:jcrdoj:v:4:y:2017:i:3:p:62-66
    DOI: 10.19080/CRDOJ.2017.04.555639
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    References listed on IDEAS

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    1. Frédéric Picard & Martin Kurtev & Namjin Chung & Acharawan Topark-Ngarm & Thanaset Senawong & Rita Machado de Oliveira & Mark Leid & Michael W. McBurney & Leonard Guarente, 2004. "Sirt1 promotes fat mobilization in white adipocytes by repressing PPAR-γ," Nature, Nature, vol. 429(6993), pages 771-776, June.
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    More about this item

    Keywords

    juniper publishers; diabetes journals; diabetes impact factor; endocrinology journal; endocrinology impact factor; endocrinology research journal; endocrinology research articles; diabetes open access journals; Obesity Journal; Diabetes & Obesity Journal;
    All these keywords.

    JEL classification:

    • R00 - Urban, Rural, Regional, Real Estate, and Transportation Economics - - General - - - General
    • Z0 - Other Special Topics - - General

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