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Quantum Chemical, Molecular Docking, and ADMET Predictions of Ketorolac and its Modified Analogues

Author

Listed:
  • Moniruzzaman

    (Faculty of Engineering, Department of Applied Chemistry and Biochemical Engineering, Shizuoka University, Japan
    Department of Chemistry, University of Chittagong, Bangladesh)

  • Mohammed Jabedul Hoque

    (Faculty of Engineering, Department of Optoelectronics and Nanostructure Science, Shizuoka University, Japan)

  • Mohammad Nasir Uddin
  • Amrin Ahsan
  • Tareq Mahmud

    (Department of Chemistry, University of Chittagong, Bangladesh)

Abstract

Ketorolac (K) is a non-steroidal agent with potent analgesic and moderate anti-inflammation activity. Adverse health effect and resistant of drugs indicate the importance of the discovery of new potential candidate...

Suggested Citation

  • Moniruzzaman & Mohammed Jabedul Hoque & Mohammad Nasir Uddin & Amrin Ahsan & Tareq Mahmud, 2018. "Quantum Chemical, Molecular Docking, and ADMET Predictions of Ketorolac and its Modified Analogues," Biomedical Journal of Scientific & Technical Research, Biomedical Research Network+, LLC, vol. 11(5), pages 8723-8729, December.
    • Handle: RePEc:abf:journl:v:11:y:2018:i:5:p:8723-8729
    DOI: 10.26717/BJSTR.2018.11.002151
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    References listed on IDEAS

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    1. Michael C. Sanguinetti & Martin Tristani-Firouzi, 2006. "hERG potassium channels and cardiac arrhythmia," Nature, Nature, vol. 440(7083), pages 463-469, March.
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    More about this item

    Keywords

    Biomedical Sciences; Biomedical Research; Technical Research; Drug Design; Ketorolac; Density Functional Theory; HOMO-LUMO; Molecular Docking; ADMET Nonbonding Interactions;
    All these keywords.

    JEL classification:

    • R00 - Urban, Rural, Regional, Real Estate, and Transportation Economics - - General - - - General
    • Z0 - Other Special Topics - - General

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