IDEAS home Printed from https://ideas.repec.org/p/iza/izadps/dp7999.html
   My bibliography  Save this paper

A Validation Study of Transgenerational Effects of Childhood Conditions on the Third Generation Offspring's Economic and Health Outcomes Potentially Driven by Epigenetic Imprinting

Author

Listed:
  • van den Berg, Gerard J.

    (University of Groningen)

  • Pinger, Pia

    (University of Cologne)

Abstract

At the crossroads of economics and human biology, this paper examines the extent to which pre-puberty nutritional conditions in one generation affect productivity-related outcomes in later generations. Recent studies have found a negative association between conditions at ages 8-12 and the grandchild's over-all and cardiovascular and diabetes mortality in a single historical dataset. It has been argued that this association reflects epigenetic imprinting, which has been corroborated in animal studies. We provide an external validation by analyzing the impact of the German famine of 1916-1918 on children and grandchildren of those exposed to the famine at ages 8-12. Our findings support and extend the evidence so far. Among the third generation, males (females) tend to have higher mental health scores if their paternal grandfather (maternal grandmother) was exposed. We do not find robust effects on the probability of obtaining an upper secondary education.

Suggested Citation

  • van den Berg, Gerard J. & Pinger, Pia, 2014. "A Validation Study of Transgenerational Effects of Childhood Conditions on the Third Generation Offspring's Economic and Health Outcomes Potentially Driven by Epigenetic Imprinting," IZA Discussion Papers 7999, Institute of Labor Economics (IZA).
  • Handle: RePEc:iza:izadps:dp7999
    as

    Download full text from publisher

    File URL: https://docs.iza.org/dp7999.pdf
    Download Restriction: no
    ---><---

    References listed on IDEAS

    as
    1. Gerard J. van den Berg & Pia R. Pinger & Johannes Schoch, 2016. "Instrumental Variable Estimation of the Causal Effect of Hunger Early in Life on Health Later in Life," Economic Journal, Royal Economic Society, vol. 126(591), pages 465-506, March.
    2. van den Berg, G. J & Lundborg P & Nystedt P & Rooth D, 2009. "Critical Periods During Childhood and Adolescence: A Study of Adult Height Among Immigrant Siblings," Health, Econometrics and Data Group (HEDG) Working Papers 09/20, HEDG, c/o Department of Economics, University of York.
    3. Gerard van den Berg & Gabriele Doblhammer-Reiter & Kaare Christensen, 2011. "Being Born Under Adverse Economic Conditions Leads to a Higher Cardiovascular Mortality Rate Later in Life: Evidence Based on Individuals Born at Different Stages of the Business Cycle," Demography, Springer;Population Association of America (PAA), vol. 48(2), pages 507-530, May.
    4. Sunder, Marco & Woitek, Ulrich, 2005. "Boom, bust, and the human body: Further evidence on the relationship between height and business cycles," Economics & Human Biology, Elsevier, vol. 3(3), pages 450-466, December.
    5. Scholte, Robert S. & van den Berg, Gerard J. & Lindeboom, Maarten, 2015. "Long-run effects of gestation during the Dutch Hunger Winter famine on labor market and hospitalization outcomes," Journal of Health Economics, Elsevier, vol. 39(C), pages 17-30.
    6. Matthias Nübling & Hanfried H. Andersen & Axel Mühlbacher & Jürgen Schupp & Gert G. Wagner, 2007. "Computation of Standard Values for Physical and Mental Health Scale Scores Using the SOEP Version of SF12v2," Schmollers Jahrbuch : Journal of Applied Social Science Studies / Zeitschrift für Wirtschafts- und Sozialwissenschaften, Duncker & Humblot, Berlin, vol. 127(1), pages 171-182.
    7. Richard H. Steckel, 2008. "Biological Measures of the Standard of Living," Journal of Economic Perspectives, American Economic Association, vol. 22(1), pages 129-152, Winter.
    8. Woitek, Ulrich, 2003. "Height cycles in the 18th and 19th centuries," Economics & Human Biology, Elsevier, vol. 1(2), pages 243-257, June.
    9. Gert G. Wagner & Joachim R. Frick & Jürgen Schupp, 2007. "The German Socio-Economic Panel Study (SOEP) – Scope, Evolution and Enhancements," Schmollers Jahrbuch : Journal of Applied Social Science Studies / Zeitschrift für Wirtschafts- und Sozialwissenschaften, Duncker & Humblot, Berlin, vol. 127(1), pages 139-169.
    10. Gabriele Doblhammer & Gerard J van den Berg & Thomas Fritze, 2013. "Economic Conditions at the Time of Birth and Cognitive Abilities Late in Life: Evidence from Ten European Countries," PLOS ONE, Public Library of Science, vol. 8(9), pages 1-12, September.
    11. Blum, Matthias, 2011. "Government decisions before and during the First World War and the living standards in Germany during a drastic natural experiment," Explorations in Economic History, Elsevier, vol. 48(4), pages 556-567.
    12. Wolfgang Mayer & Alain Niveleau & Jörn Walter & Reinald Fundele & Thomas Haaf, 2000. "Demethylation of the zygotic paternal genome," Nature, Nature, vol. 403(6769), pages 501-502, February.
    13. Lundborg, Petter & Stenberg, Anders, 2010. "Nature, nurture and socioeconomic policy--What can we learn from molecular genetics?," Economics & Human Biology, Elsevier, vol. 8(3), pages 320-330, December.
    14. Mamelund, Svenn-Erik, 2003. "Effects of the Spanish Influenza Pandemic of 1918-19 on Later Life Mortality of Norwegian Cohorts Born About 1900," Memorandum 29/2003, Oslo University, Department of Economics.
    15. Lindeboom, Maarten & Portrait, France & van den Berg, Gerard J., 2010. "Long-run effects on longevity of a nutritional shock early in life: The Dutch Potato famine of 1846-1847," Journal of Health Economics, Elsevier, vol. 29(5), pages 617-629, September.
    Full references (including those not matched with items on IDEAS)

    Citations

    Citations are extracted by the CitEc Project, subscribe to its RSS feed for this item.
    as


    Cited by:

    1. Gerard J. van den Berg & Pia R. Pinger & Johannes Schoch, 2016. "Instrumental Variable Estimation of the Causal Effect of Hunger Early in Life on Health Later in Life," Economic Journal, Royal Economic Society, vol. 126(591), pages 465-506, March.
    2. Tan, Chih Ming & Tan, Zhibo & Zhang, Xiaobo, 2014. "Sins of the fathers: The intergenerational legacy of the 1959-1961 Great Chinese Famine on children's cognitive development:," IFPRI discussion papers 1351, International Food Policy Research Institute (IFPRI).
    3. C. Justin Cook & Jason M. Fletcher & Angela Forgues, 2019. "Multigenerational Effects of Early-Life Health Shocks," Demography, Springer;Population Association of America (PAA), vol. 56(5), pages 1855-1874, October.
    4. Richter, André & Robling, Per Olof, 2013. "Multigenerational e ffects of the 1918-19 influenza pandemic in Sweden," Working Paper Series 5/2013, Stockholm University, Swedish Institute for Social Research.

    Most related items

    These are the items that most often cite the same works as this one and are cited by the same works as this one.
    1. van den Berg, Gerard J. & Pinger, Pia R., 2016. "Transgenerational effects of childhood conditions on third generation health and education outcomes," Economics & Human Biology, Elsevier, vol. 23(C), pages 103-120.
    2. Gerard J. van den Berg & Pia R. Pinger & Johannes Schoch, 2016. "Instrumental Variable Estimation of the Causal Effect of Hunger Early in Life on Health Later in Life," Economic Journal, Royal Economic Society, vol. 126(591), pages 465-506, March.
    3. Scholte, Robert S. & van den Berg, Gerard J. & Lindeboom, Maarten, 2015. "Long-run effects of gestation during the Dutch Hunger Winter famine on labor market and hospitalization outcomes," Journal of Health Economics, Elsevier, vol. 39(C), pages 17-30.
    4. van den Berg, Gerard J. & Gupta, Sumedha, 2015. "The role of marriage in the causal pathway from economic conditions early in life to mortality," Journal of Health Economics, Elsevier, vol. 40(C), pages 141-158.
    5. Fritze, Thomas & Doblhammer, Gabriele & van den Berg, Gerard J., 2014. "Can individual conditions during childhood mediate or moderate the long-term cognitive effects of poor economic environments at birth?," Social Science & Medicine, Elsevier, vol. 119(C), pages 240-248.
    6. Komlos, John, 2012. "A Three-Decade “Kuhnian” History of the Antebellum Puzzle: Explaining the shrinking of the US population at the onset of modern economic growth," Discussion Papers in Economics 12758, University of Munich, Department of Economics.
    7. Denis Cogneau & Lionel Kesztenbaum, 2016. "Short and long-term impacts of famines: The case of the siege of Paris 1870-1871," Working Papers halshs-01321939, HAL.
    8. Conti, Gabriella & Poupakis, Stavros & Ekamper, Peter & Bijwaard, Govert E. & Lumey, L.H., 2024. "Severe prenatal shocks and adolescent health: Evidence from the Dutch Hunger Winter," Economics & Human Biology, Elsevier, vol. 53(C).
    9. Gevrek, Deniz & Guven, Cahit & Gevrek, Z. Eylem, 2022. "The relationship between early-life conditions in the home country and adult outcomes among child immigrants in the United States," Economics & Human Biology, Elsevier, vol. 45(C).
    10. Andreella, Claudia & Karlsson, Martin & Nilsson, Therese & Westphal, Matthias, 2015. "The long shadows of past insults intergenerational transmission of health over 130 years," Ruhr Economic Papers 571, RWI - Leibniz-Institut für Wirtschaftsforschung, Ruhr-University Bochum, TU Dortmund University, University of Duisburg-Essen.
    11. Steckel, Richard H., 2009. "Heights and human welfare: Recent developments and new directions," Explorations in Economic History, Elsevier, vol. 46(1), pages 1-23, January.
    12. Komlos, John, 2019. "Shrinking in a growing economy is not so puzzling after all," Economics & Human Biology, Elsevier, vol. 32(C), pages 40-55.
    13. Gabriella Conti, 2013. "The Developmental Origins of Health Inequality," Research on Economic Inequality, in: Health and Inequality, volume 21, pages 285-309, Emerald Group Publishing Limited.
    14. Reyn van Ewijk & Maarten Lindeboom, 2016. "Why people born during World War II are healthier," Working Papers 1619, Gutenberg School of Management and Economics, Johannes Gutenberg-Universität Mainz.
    15. Schoch, Tobias & Staub, Kaspar & Pfister, Christian, 2012. "Social inequality and the biological standard of living: An anthropometric analysis of Swiss conscription data, 1875–1950," Economics & Human Biology, Elsevier, vol. 10(2), pages 154-173.
    16. Komlos, John & A’Hearn, Brian, 2017. "Hidden negative aspects of industrialization at the onset of modern economic growth in the U.S," Structural Change and Economic Dynamics, Elsevier, vol. 41(C), pages 43-52.
    17. Jürges, Hendrik, 2013. "Collateral damage: The German food crisis, educational attainment and labor market outcomes of German post-war cohorts," Journal of Health Economics, Elsevier, vol. 32(1), pages 286-303.
    18. Dragone, D. & Ziebarth, N.R., 2015. "Non-Separable Time Preferences and Novelty Consumption: Theory and Evidence from the East German Transition to Capitalism," Health, Econometrics and Data Group (HEDG) Working Papers 15/28, HEDG, c/o Department of Economics, University of York.
    19. Sunder, Marco, 2013. "The height gap in 19th-century America: Net-nutritional advantage of the elite increased at the onset of modern economic growth," Economics & Human Biology, Elsevier, vol. 11(3), pages 245-258.
    20. Jo Mhairi Hale, 2017. "Cognitive Disparities: The Impact of the Great Depression and Cumulative Inequality on Later-Life Cognitive Function," Demography, Springer;Population Association of America (PAA), vol. 54(6), pages 2125-2158, December.

    More about this item

    Keywords

    famine; transgenerational transmission; epigenetics; mental health; education; long-run effects; nutrition; intergenerational effects; slow-growth period;
    All these keywords.

    JEL classification:

    • I12 - Health, Education, and Welfare - - Health - - - Health Behavior
    • J11 - Labor and Demographic Economics - - Demographic Economics - - - Demographic Trends, Macroeconomic Effects, and Forecasts

    NEP fields

    This paper has been announced in the following NEP Reports:

    Statistics

    Access and download statistics

    Corrections

    All material on this site has been provided by the respective publishers and authors. You can help correct errors and omissions. When requesting a correction, please mention this item's handle: RePEc:iza:izadps:dp7999. See general information about how to correct material in RePEc.

    If you have authored this item and are not yet registered with RePEc, we encourage you to do it here. This allows to link your profile to this item. It also allows you to accept potential citations to this item that we are uncertain about.

    If CitEc recognized a bibliographic reference but did not link an item in RePEc to it, you can help with this form .

    If you know of missing items citing this one, you can help us creating those links by adding the relevant references in the same way as above, for each refering item. If you are a registered author of this item, you may also want to check the "citations" tab in your RePEc Author Service profile, as there may be some citations waiting for confirmation.

    For technical questions regarding this item, or to correct its authors, title, abstract, bibliographic or download information, contact: Holger Hinte (email available below). General contact details of provider: https://edirc.repec.org/data/izaaade.html .

    Please note that corrections may take a couple of weeks to filter through the various RePEc services.

    IDEAS is a RePEc service. RePEc uses bibliographic data supplied by the respective publishers.