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Modelling latent trends from spatio-temporally grouped data using composite link mixed models

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  • Ayma Anza, Diego Armando
  • Durbán, María
  • Lee, Dae-Jin
  • Van de Kassteele, Jan

Abstract

Epidemiological data are frequently recorded at coarse spatio-temporal resolutions. The aggregation process is done for several reasons: to protect confidential patients' information, to compare with other datasets at a coarser resolution than the original, or to summarize data in a compact manner. However, we lose detailed patterns that follow the original data, which can be of interest for researchers and public health officials. In this paper we propose the use of the penalized composite link model (Eilers, 2007), together with its mixed model representation, to estimate the underlying trend behind grouped data at a finer spatio-temporal resolution. Also, this model allows the incorporation of fine-scale population into the estimation procedure. We assume the underlying trend is smooth across space and time. The mixed model representation enables the use of sophisticated algorithms such as the SAP algorithm of RodríguezÁlvarez et al. (2015) for fast estimation of the amount of smoothness. We illustrate our proposal with the analysis of data obtained during the largest outbreak of Q fever in the Netherlands.

Suggested Citation

  • Ayma Anza, Diego Armando & Durbán, María & Lee, Dae-Jin & Van de Kassteele, Jan, 2016. "Modelling latent trends from spatio-temporally grouped data using composite link mixed models," DES - Working Papers. Statistics and Econometrics. WS 23448, Universidad Carlos III de Madrid. Departamento de Estadística.
    • Handle: RePEc:cte:wsrepe:23448
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    References listed on IDEAS

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    1. I. D. Currie & M. Durban & P. H. C. Eilers, 2006. "Generalized linear array models with applications to multidimensional smoothing," Journal of the Royal Statistical Society Series B, Royal Statistical Society, vol. 68(2), pages 259-280, April.
    2. Eilers, Paul H.C. & Currie, Iain D. & Durban, Maria, 2006. "Fast and compact smoothing on large multidimensional grids," Computational Statistics & Data Analysis, Elsevier, vol. 50(1), pages 61-76, January.
    3. Håvard Rue & Sara Martino & Nicolas Chopin, 2009. "Approximate Bayesian inference for latent Gaussian models by using integrated nested Laplace approximations," Journal of the Royal Statistical Society Series B, Royal Statistical Society, vol. 71(2), pages 319-392, April.
    4. X. Lin & D. Zhang, 1999. "Inference in generalized additive mixed modelsby using smoothing splines," Journal of the Royal Statistical Society Series B, Royal Statistical Society, vol. 61(2), pages 381-400, April.
    5. Ying C. MacNab & C. B. Dean, 2001. "Autoregressive Spatial Smoothing and Temporal Spline Smoothing for Mapping Rates," Biometrics, The International Biometric Society, vol. 57(3), pages 949-956, September.
    6. R. Thompson & R. J. Baker, 1981. "Composite Link Functions in Generalized Linear Models," Journal of the Royal Statistical Society Series C, Royal Statistical Society, vol. 30(2), pages 125-131, June.
    7. Lauren Hund & Jarvis T. Chen & Nancy Krieger & Brent A. Coull, 2012. "A Geostatistical Approach to Large-Scale Disease Mapping with Temporal Misalignment," Biometrics, The International Biometric Society, vol. 68(3), pages 849-858, September.
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    Penalized composite link models;

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