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Anti-depressants, suicide, and drug regulation

Author

Listed:
  • Jens Ludwig

    (Georgetown University)

  • Dave E. Marcotte

    (University of Maryland, Baltimore County)

Abstract

Policymakers are increasingly concerned that a relatively new class of anti-depressant drugs, selective serotonin re-uptake inhibitors (SSRI), may increase the risk of suicide for at least some patients, particularly children. Prior randomized trials are not informative on this question because of small sample sizes and other limitations. Using variation across countries over time in SSRI sales and suicide, we find that an increase of one pill per capita (a 13 percent increase over 1999 levels) is associated with a 2.5 percent reduction in suicide rates, a relationship that is more pronounced for adults than for children. Our findings suggest that expanding access to SSRIs for adults may be a cost-effective way to save lives, although policymakers are right to remain cautious about pediatric use of SSRIs. © 2005 by the Association for Public Policy Analysis and Management

Suggested Citation

  • Jens Ludwig & Dave E. Marcotte, 2005. "Anti-depressants, suicide, and drug regulation," Journal of Policy Analysis and Management, John Wiley & Sons, Ltd., vol. 24(2), pages 249-272.
    • Handle: RePEc:wly:jpamgt:v:24:y:2005:i:2:p:249-272
    DOI: 10.1002/pam.20089
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    References listed on IDEAS

    as
    1. Morrall, John F, III, 2003. "Saving Lives: A Review of the Record," Journal of Risk and Uncertainty, Springer, vol. 27(3), pages 221-237, December.
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    5. Dahlberg, Matz & Lundin, Douglas, 2005. "Antidepressants and the Suicide Rate: Is There Really a Connection?," Working Paper Series 2005:4, Uppsala University, Department of Economics.
    6. repec:reg:rpubli:282 is not listed on IDEAS
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    Cited by:

    1. Ludwig, Jens & Marcotte, Dave E. & Norberg, Karen, 2009. "Anti-depressants and suicide," Journal of Health Economics, Elsevier, vol. 28(3), pages 659-676, May.
    2. Kristy Parkinson & Joseph Price & Kosali Simon & Sharon Tennyson, 2014. "The influence of FDA advisory information and black box warnings on individual use of prescription antidepressants," Review of Economics of the Household, Springer, vol. 12(4), pages 771-790, December.
    3. Katolik, Aleksandra & Oswald, Andrew J., 2017. "Antidepressants for Economists and Business-School Researchers: An Introduction and Review," Die Unternehmung - Swiss Journal of Business Research and Practice, Nomos Verlagsgesellschaft mbH & Co. KG, vol. 71(4), pages 448-463.
    4. Cuellar, Alison Evans & Markowitz, Sara, 2007. "Medicaid policy changes in mental health care and their effect on mental health outcomes," Health Economics, Policy and Law, Cambridge University Press, vol. 2(1), pages 23-49, January.
    5. Dahlberg, Matz & Lundin, Douglas, 2005. "Antidepressants and the Suicide Rate: Is There Really a Connection?," Working Paper Series 2005:4, Uppsala University, Department of Economics.
    6. Markowitz, Sara & Cuellar, Alison, 2007. "Antidepressants and youth: Healing or harmful?," Social Science & Medicine, Elsevier, vol. 64(10), pages 2138-2151, May.
    7. Katolik, Aleksandra & Oswald, Andrew J., 2017. "Antidepressants for Economists and Business-School Researchers: An Introduction and Review," CAGE Online Working Paper Series 338, Competitive Advantage in the Global Economy (CAGE).
    8. Manoj K. Pandey & Charanjit Kaur, 2009. "Investigating Suicidal Trend and its Economic Determinants: Evidence from India," ASARC Working Papers 2009-08, The Australian National University, Australia South Asia Research Centre.

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