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Self‐rated health mediates the association between functional status and health‐related quality of life in Parkinson's disease

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  • Radka Ghorbani Saeedian
  • Iveta Nagyova
  • Daniel Klein
  • Matej Skorvanek
  • Jaroslav Rosenberger
  • Zuzana Gdovinova
  • Johan W Groothoff
  • Jitse P van Dijk

Abstract

Aims and objectives To explore whether self‐rated health acts as a potential mediator in the association between functional status and health‐related quality of life in Parkinson's disease. Background Older persons (as most patients with Parkinson's disease are) who reported poor self‐rated health compared with those with excellent self‐rated health were two‐and‐a‐half times more likely to have experienced a decline in functional ability. Design Cross‐sectional. Methods Socio‐demographic and clinical data of the patients (n = 176) were obtained during a structured interview and from medical records. Functional status was measured with the Unified Parkinson's Disease Rating Scale (total score), self‐rated health with the first item of the Short‐Form 36‐item Health Survey Questionnaire and health‐related quality of life with the disease‐specific questionnaire called the Parkinson's Disease Quality of Life Questionnaire‐39. Multiple linear regression analyses and the Sobel test were employed to assess mediation. Results Self‐rated health seems to have a mediating effect on the association between functional status and health‐related quality of life. The Sobel test confirmed an indirect effect of functional status via self‐rated health on health‐related quality of life and showed a statistically significant indirect effect of functional status on health‐related quality of life via self‐rated health against the direct route without the mediator. Conclusions Self‐rated health partially mediates the deteriorating effect of functional status on health‐related quality of life. Relevance to clinical practice Supportive and adaptation psychosocial intervention programmes leading to restored self‐rated health may enhance the quality of life regardless of disability in Parkinson's disease.

Suggested Citation

  • Radka Ghorbani Saeedian & Iveta Nagyova & Daniel Klein & Matej Skorvanek & Jaroslav Rosenberger & Zuzana Gdovinova & Johan W Groothoff & Jitse P van Dijk, 2014. "Self‐rated health mediates the association between functional status and health‐related quality of life in Parkinson's disease," Journal of Clinical Nursing, John Wiley & Sons, vol. 23(13-14), pages 1970-1977, July.
    • Handle: RePEc:wly:jocnur:v:23:y:2014:i:13-14:p:1970-1977
    DOI: 10.1111/jocn.12442
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