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Optimal Control Analysis of a Mathematical Model for Recurrent Malaria Dynamics

Author

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  • Samson Olaniyi

    (Ladoke Akintola University of Technology)

  • Olusegun A. Ajala

    (Ladoke Akintola University of Technology)

  • Sulaimon F. Abimbade

    (Ladoke Akintola University of Technology)

Abstract

Recurrence of malaria symptoms after treatment constitutes one of the major factors affecting malaria control in the population. The transmission of malaria will persist in the population, if effective and considerable control measures are not put in place. In this study, a time-dependent deterministic mathematical model focusing on the role of preventing and controlling the transmission dynamics of recurrent malaria is considered and analyzed. The formulated non-autonomous model is justified by exploring the sensitivities of the basic reproduction number to changes in the parameters of its time-invariant version. By using optimal control theory, the existence of four optimal control functions, including personal preventive effort against mosquito bites, anti-relapse measure, anti-malaria treatment and insecticide spraying, is qualitatively established and the control quadruple is characterized using Pontryagin’s maximum principle. Numerical simulations of the optimal control problem are conducted to show the effects of doubling optimal control functions on the recurrent malaria system through graphical demonstrations.

Suggested Citation

  • Samson Olaniyi & Olusegun A. Ajala & Sulaimon F. Abimbade, 2023. "Optimal Control Analysis of a Mathematical Model for Recurrent Malaria Dynamics," SN Operations Research Forum, Springer, vol. 4(1), pages 1-24, March.
    • Handle: RePEc:spr:snopef:v:4:y:2023:i:1:d:10.1007_s43069-023-00197-5
    DOI: 10.1007/s43069-023-00197-5
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    References listed on IDEAS

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    1. Li, Tingting & Guo, Youming, 2022. "Modeling and optimal control of mutated COVID-19 (Delta strain) with imperfect vaccination," Chaos, Solitons & Fractals, Elsevier, vol. 156(C).
    2. Ndii, Meksianis Z. & Adi, Yudi Ari, 2021. "Understanding the effects of individual awareness and vector controls on malaria transmission dynamics using multiple optimal control," Chaos, Solitons & Fractals, Elsevier, vol. 153(P1).
    3. Abid Ali Lashari & Shaban Aly & Khalid Hattaf & Gul Zaman & Il Hyo Jung & Xue-Zhi Li, 2012. "Presentation of Malaria Epidemics Using Multiple Optimal Controls," Journal of Applied Mathematics, Hindawi, vol. 2012, pages 1-17, June.
    4. Ghosh, M. & Olaniyi, S. & Obabiyi, O.S., 2020. "Mathematical analysis of reinfection and relapse in malaria dynamics," Applied Mathematics and Computation, Elsevier, vol. 373(C).
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    Cited by:

    1. Samson Olaniyi & Sulaimon F. Abimbade & Olusegun A. Ajala & Furaha M. Chuma, 2024. "Efficiency and economic analysis of intervention strategies for recurrent malaria transmission," Quality & Quantity: International Journal of Methodology, Springer, vol. 58(1), pages 627-645, February.

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