IDEAS home Printed from https://ideas.repec.org/a/spr/lifeda/v29y2023i1d10.1007_s10985-022-09575-3.html
   My bibliography  Save this article

A general class of promotion time cure rate models with a new biological interpretation

Author

Listed:
  • Yolanda M. Gómez

    (Universidad de Atacama)

  • Diego I. Gallardo

    (Universidad de Atacama
    Universidad de Atacama)

  • Marcelo Bourguignon

    (Universidade Federal do Rio Grande do Norte)

  • Eduardo Bertolli

    (A.C.Camargo Cancer Center
    Beneficência Portuguesa)

  • Vinicius F. Calsavara

    (Cedars-Sinai Medical Center)

Abstract

Over the last decades, the challenges in survival models have been changing considerably and full probabilistic modeling is crucial in many medical applications. Motivated from a new biological interpretation of cancer metastasis, we introduce a general method for obtaining more flexible cure rate models. The proposal model extended the promotion time cure rate model. Furthermore, it includes several well-known models as special cases and defines many new special models. We derive several properties of the hazard function for the proposed model and establish mathematical relationships with the promotion time cure rate model. We consider a frequentist approach to perform inferences, and the maximum likelihood method is employed to estimate the model parameters. Simulation studies are conducted to evaluate its performance with a discussion of the obtained results. A real dataset from population-based study of incident cases of melanoma diagnosed in the state of São Paulo, Brazil, is discussed in detail.

Suggested Citation

  • Yolanda M. Gómez & Diego I. Gallardo & Marcelo Bourguignon & Eduardo Bertolli & Vinicius F. Calsavara, 2023. "A general class of promotion time cure rate models with a new biological interpretation," Lifetime Data Analysis: An International Journal Devoted to Statistical Methods and Applications for Time-to-Event Data, Springer, vol. 29(1), pages 66-86, January.
    • Handle: RePEc:spr:lifeda:v:29:y:2023:i:1:d:10.1007_s10985-022-09575-3
    DOI: 10.1007/s10985-022-09575-3
    as

    Download full text from publisher

    File URL: http://link.springer.com/10.1007/s10985-022-09575-3
    File Function: Abstract
    Download Restriction: Access to the full text of the articles in this series is restricted.
    File URL: https://libkey.io/10.1007/s10985-022-09575-3?utm_source=ideas
    LibKey link: if access is restricted and if your library uses this service, LibKey will redirect you to where you can use your library subscription to access this item
    ---><---

    As the access to this document is restricted, you may want to search for a different version of it.

    References listed on IDEAS

    as
    1. Guosheng Yin & Joseph G. Ibrahim, 2005. "A General Class of Bayesian Survival Models with Zero and Nonzero Cure Fractions," Biometrics, The International Biometric Society, vol. 61(2), pages 403-412, June.
    2. Li, Chin-Shang & Taylor, Jeremy M. G. & Sy, Judy P., 2001. "Identifiability of cure models," Statistics & Probability Letters, Elsevier, vol. 54(4), pages 389-395, October.
    3. Hanin, Leonid & Huang, Li-Shan, 2014. "Identifiability of cure models revisited," Journal of Multivariate Analysis, Elsevier, vol. 130(C), pages 261-274.
    4. Cooner, Freda & Banerjee, Sudipto & Carlin, Bradley P. & Sinha, Debajyoti, 2007. "Flexible Cure Rate Modeling Under Latent Activation Schemes," Journal of the American Statistical Association, American Statistical Association, vol. 102, pages 560-572, June.
    5. R. A. Rigby & D. M. Stasinopoulos, 2005. "Generalized additive models for location, scale and shape," Journal of the Royal Statistical Society Series C, Royal Statistical Society, vol. 54(3), pages 507-554, June.
    6. Stasinopoulos, D. Mikis & Rigby, Robert A., 2007. "Generalized Additive Models for Location Scale and Shape (GAMLSS) in R," Journal of Statistical Software, Foundation for Open Access Statistics, vol. 23(i07).
    Full references (including those not matched with items on IDEAS)

    Most related items

    These are the items that most often cite the same works as this one and are cited by the same works as this one.
    1. Borges, Patrick & Rodrigues, Josemar & Balakrishnan, Narayanaswamy, 2012. "Correlated destructive generalized power series cure rate models and associated inference with an application to a cutaneous melanoma data," Computational Statistics & Data Analysis, Elsevier, vol. 56(6), pages 1703-1713.
    2. Thiago G. Ramires & Niel Hens & Gauss M. Cordeiro & Edwin M. M. Ortega, 2018. "Estimating nonlinear effects in the presence of cure fraction using a semi-parametric regression model," Computational Statistics, Springer, vol. 33(2), pages 709-730, June.
    3. Olayidé Boussari & Laurent Bordes & Gaëlle Romain & Marc Colonna & Nadine Bossard & Laurent Remontet & Valérie Jooste, 2021. "Modeling excess hazard with time‐to‐cure as a parameter," Biometrics, The International Biometric Society, vol. 77(4), pages 1289-1302, December.
    4. Yixuan Wang & Jianzhu Li & Ping Feng & Rong Hu, 2015. "A Time-Dependent Drought Index for Non-Stationary Precipitation Series," Water Resources Management: An International Journal, Published for the European Water Resources Association (EWRA), Springer;European Water Resources Association (EWRA), vol. 29(15), pages 5631-5647, December.
    5. Panayi, Efstathios & Peters, Gareth W. & Danielsson, Jon & Zigrand, Jean-Pierre, 2018. "Designating market maker behaviour in limit order book markets," Econometrics and Statistics, Elsevier, vol. 5(C), pages 20-44.
    6. Gauss Cordeiro & Josemar Rodrigues & Mário Castro, 2012. "The exponential COM-Poisson distribution," Statistical Papers, Springer, vol. 53(3), pages 653-664, August.
    7. Christian Kleiber & Achim Zeileis, 2016. "Visualizing Count Data Regressions Using Rootograms," The American Statistician, Taylor & Francis Journals, vol. 70(3), pages 296-303, July.
    8. Matteo Malavasi & Gareth W. Peters & Pavel V. Shevchenko & Stefan Truck & Jiwook Jang & Georgy Sofronov, 2021. "Cyber Risk Frequency, Severity and Insurance Viability," Papers 2111.03366, arXiv.org, revised Mar 2022.
    9. Lucio Masserini & Matilde Bini & Monica Pratesi, 2017. "Effectiveness of non-selective evaluation test scores for predicting first-year performance in university career: a zero-inflated beta regression approach," Quality & Quantity: International Journal of Methodology, Springer, vol. 51(2), pages 693-708, March.
    10. Tong, Edward N.C. & Mues, Christophe & Thomas, Lyn, 2013. "A zero-adjusted gamma model for mortgage loan loss given default," International Journal of Forecasting, Elsevier, vol. 29(4), pages 548-562.
    11. Alexander Silbersdorff & Kai Sebastian Schneider, 2019. "Distributional Regression Techniques in Socioeconomic Research on the Inequality of Health with an Application on the Relationship between Mental Health and Income," IJERPH, MDPI, vol. 16(20), pages 1-28, October.
    12. Suvra Pal & N. Balakrishnan, 2017. "Likelihood inference for the destructive exponentially weighted Poisson cure rate model with Weibull lifetime and an application to melanoma data," Computational Statistics, Springer, vol. 32(2), pages 429-449, June.
    13. Tong, Edward N.C. & Mues, Christophe & Brown, Iain & Thomas, Lyn C., 2016. "Exposure at default models with and without the credit conversion factor," European Journal of Operational Research, Elsevier, vol. 252(3), pages 910-920.
    14. Micha{l} Narajewski & Florian Ziel, 2020. "Ensemble Forecasting for Intraday Electricity Prices: Simulating Trajectories," Papers 2005.01365, arXiv.org, revised Aug 2020.
    15. D. Chiru Naik & Sagar Rohidas Chavan & P. Sonali, 2023. "Incorporating the climate oscillations in the computation of meteorological drought over India," Natural Hazards: Journal of the International Society for the Prevention and Mitigation of Natural Hazards, Springer;International Society for the Prevention and Mitigation of Natural Hazards, vol. 117(3), pages 2617-2646, July.
    16. Shuhui Guo & Lihua Xiong & Jie Chen & Shenglian Guo & Jun Xia & Ling Zeng & Chong-Yu Xu, 2023. "Nonstationary Regional Flood Frequency Analysis Based on the Bayesian Method," Water Resources Management: An International Journal, Published for the European Water Resources Association (EWRA), Springer;European Water Resources Association (EWRA), vol. 37(2), pages 659-681, January.
    17. Maike Hohberg & Katja Landau & Thomas Kneib & Stephan Klasen & Walter Zucchini, 2018. "Vulnerability to poverty revisited: Flexible modeling and better predictive performance," The Journal of Economic Inequality, Springer;Society for the Study of Economic Inequality, vol. 16(3), pages 439-454, September.
    18. Kuntz, Laura-Chloé, 2020. "Beta dispersion and market timing," Journal of Empirical Finance, Elsevier, vol. 59(C), pages 235-256.
    19. Epstein, Leonardo D. & Inostroza-Quezada, Ignacio E. & Goodstein, Ronald C. & Choi, S. Chan, 2021. "Dynamic effects of store promotions on purchase conversion: Expanding technology applications with innovative analytics," Journal of Business Research, Elsevier, vol. 128(C), pages 279-289.
    20. Serinaldi, Francesco, 2011. "Distributional modeling and short-term forecasting of electricity prices by Generalized Additive Models for Location, Scale and Shape," Energy Economics, Elsevier, vol. 33(6), pages 1216-1226.

    Corrections

    All material on this site has been provided by the respective publishers and authors. You can help correct errors and omissions. When requesting a correction, please mention this item's handle: RePEc:spr:lifeda:v:29:y:2023:i:1:d:10.1007_s10985-022-09575-3. See general information about how to correct material in RePEc.

    If you have authored this item and are not yet registered with RePEc, we encourage you to do it here. This allows to link your profile to this item. It also allows you to accept potential citations to this item that we are uncertain about.

    If CitEc recognized a bibliographic reference but did not link an item in RePEc to it, you can help with this form .

    If you know of missing items citing this one, you can help us creating those links by adding the relevant references in the same way as above, for each refering item. If you are a registered author of this item, you may also want to check the "citations" tab in your RePEc Author Service profile, as there may be some citations waiting for confirmation.

    For technical questions regarding this item, or to correct its authors, title, abstract, bibliographic or download information, contact: Sonal Shukla or Springer Nature Abstracting and Indexing (email available below). General contact details of provider: http://www.springer.com .

    Please note that corrections may take a couple of weeks to filter through the various RePEc services.

    IDEAS is a RePEc service. RePEc uses bibliographic data supplied by the respective publishers.