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The wild bootstrap for multivariate Nelson–Aalen estimators

Author

Listed:
  • Tobias Bluhmki

    (Ulm University)

  • Dennis Dobler

    (Vrije Universiteit Amsterdam)

  • Jan Beyersmann

    (Ulm University)

  • Markus Pauly

    (Ulm University)

Abstract

We rigorously extend the widely used wild bootstrap resampling technique to the multivariate Nelson–Aalen estimator under Aalen’s multiplicative intensity model. Aalen’s model covers general Markovian multistate models including competing risks subject to independent left-truncation and right-censoring. This leads to various statistical applications such as asymptotically valid confidence bands or tests for equivalence and proportional hazards. This is exemplified in a data analysis examining the impact of ventilation on the duration of intensive care unit stay. The finite sample properties of the new procedures are investigated in a simulation study.

Suggested Citation

  • Tobias Bluhmki & Dennis Dobler & Jan Beyersmann & Markus Pauly, 2019. "The wild bootstrap for multivariate Nelson–Aalen estimators," Lifetime Data Analysis: An International Journal Devoted to Statistical Methods and Applications for Time-to-Event Data, Springer, vol. 25(1), pages 97-127, January.
    • Handle: RePEc:spr:lifeda:v:25:y:2019:i:1:d:10.1007_s10985-018-9423-x
    DOI: 10.1007/s10985-018-9423-x
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    References listed on IDEAS

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