IDEAS home Printed from https://ideas.repec.org/a/sae/somere/v39y2010i2p157-187.html
   My bibliography  Save this article

Assessing Group Differences in Estimated Baseline Survivor Functions From Cox Proportional Hazards Models

Author

Listed:
  • Daniel A. Powers

    (University of Texas at Austin, TX, USA)

Abstract

The author discusses the general problem of evaluating differences in adjusted survivor functions and develops a heuristic approach to generate the expected events that would occur under a Cox proportional hazards model. Differences in the resulting expected survivor distributions can be tested using generalized log rank tests. This method should prove useful for making other kinds of comparisons and generating adjusted life tables. The author also discusses alternative specifications of the classical Cox model that allow time-varying effects and thus permit a more direct assessment of group differences at various points in time. He implements recently developed semiparametric approaches for estimating time-varying effects, which permit statistical tests of group difference in effects as well as tests of time-invariant effects. He shows that these approaches can provide insight into the nature of time-varying effects and can help reveal the temporal dynamic of group differences.

Suggested Citation

  • Daniel A. Powers, 2010. "Assessing Group Differences in Estimated Baseline Survivor Functions From Cox Proportional Hazards Models," Sociological Methods & Research, , vol. 39(2), pages 157-187, November.
    • Handle: RePEc:sae:somere:v:39:y:2010:i:2:p:157-187
    DOI: 10.1177/0049124110384064
    as

    Download full text from publisher

    File URL: https://journals.sagepub.com/doi/10.1177/0049124110384064
    Download Restriction: no
    File URL: https://libkey.io/10.1177/0049124110384064?utm_source=ideas
    LibKey link: if access is restricted and if your library uses this service, LibKey will redirect you to where you can use your library subscription to access this item
    ---><---

    References listed on IDEAS

    as
    1. Thomas H. Scheike & Torben Martinussen, 2004. "On Estimation and Tests of Time‐Varying Effects in the Proportional Hazards Model," Scandinavian Journal of Statistics, Danish Society for Theoretical Statistics;Finnish Statistical Society;Norwegian Statistical Association;Swedish Statistical Association, vol. 31(1), pages 51-62, March.
    2. Thomas H. Scheike & Mei-Jie Zhang, 2003. "Extensions and Applications of the Cox-Aalen Survival Model," Biometrics, The International Biometric Society, vol. 59(4), pages 1036-1045, December.
    3. Torben Martinussen & Thomas H. Scheike & Ib M. Skovgaard, 2002. "Efficient Estimation of Fixed and Time‐varying Covariate Effects in Multiplicative Intensity Models," Scandinavian Journal of Statistics, Danish Society for Theoretical Statistics;Finnish Statistical Society;Norwegian Statistical Association;Swedish Statistical Association, vol. 29(1), pages 57-74, March.
    Full references (including those not matched with items on IDEAS)

    Most related items

    These are the items that most often cite the same works as this one and are cited by the same works as this one.
    1. Bhattacharjee, Arnab, 2009. "Testing for Proportional Hazards with Unrestricted Univariate Unobserved Heterogeneity," SIRE Discussion Papers 2009-22, Scottish Institute for Research in Economics (SIRE).
    2. Sun, Liuquan & Zhu, Liang & Sun, Jianguo, 2009. "Regression analysis of multivariate recurrent event data with time-varying covariate effects," Journal of Multivariate Analysis, Elsevier, vol. 100(10), pages 2214-2223, November.
    3. Guanghui Wei & Douglas E. Schaubel, 2008. "Estimating Cumulative Treatment Effects in the Presence of Nonproportional Hazards," Biometrics, The International Biometric Society, vol. 64(3), pages 724-732, September.
    4. Tobias Bluhmki & Dennis Dobler & Jan Beyersmann & Markus Pauly, 2019. "The wild bootstrap for multivariate Nelson–Aalen estimators," Lifetime Data Analysis: An International Journal Devoted to Statistical Methods and Applications for Time-to-Event Data, Springer, vol. 25(1), pages 97-127, January.
    5. Yanqing Sun & Rajeshwari Sundaram & Yichuan Zhao, 2009. "Empirical Likelihood Inference for the Cox Model with Time‐dependent Coefficients via Local Partial Likelihood," Scandinavian Journal of Statistics, Danish Society for Theoretical Statistics;Finnish Statistical Society;Norwegian Statistical Association;Swedish Statistical Association, vol. 36(3), pages 444-462, September.
    6. Tobias Bluhmki & Claudia Schmoor & Dennis Dobler & Markus Pauly & Juergen Finke & Martin Schumacher & Jan Beyersmann, 2018. "A wild bootstrap approach for the Aalen–Johansen estimator," Biometrics, The International Biometric Society, vol. 74(3), pages 977-985, September.
    7. Marc Ditzhaus & Arnold Janssen, 2020. "Bootstrap and permutation rank tests for proportional hazards under right censoring," Lifetime Data Analysis: An International Journal Devoted to Statistical Methods and Applications for Time-to-Event Data, Springer, vol. 26(3), pages 493-517, July.
    8. Wang, Qizhen & Zhu, Yingming & Wang, Yudong, 2017. "The effects of oil shocks on export duration of China," Energy, Elsevier, vol. 125(C), pages 55-61.
    9. Yassin Mazroui & Audrey Mauguen & Simone Mathoulin-Pélissier & Gaetan MacGrogan & Véronique Brouste & Virginie Rondeau, 2016. "Time-varying coefficients in a multivariate frailty model: Application to breast cancer recurrences of several types and death," Lifetime Data Analysis: An International Journal Devoted to Statistical Methods and Applications for Time-to-Event Data, Springer, vol. 22(2), pages 191-215, April.
    10. Jun Yan & Jian Huang, 2009. "Partly Functional Temporal Process Regression with Semiparametric Profile Estimating Functions," Biometrics, The International Biometric Society, vol. 65(2), pages 431-440, June.
    11. Zhengnan Huang & Hongjiu Zhang & Jonathan Boss & Stephen A Goutman & Bhramar Mukherjee & Ivo D Dinov & Yuanfang Guan & for the Pooled Resource Open-Access ALS Clinical Trials Consortium, 2017. "Complete hazard ranking to analyze right-censored data: An ALS survival study," PLOS Computational Biology, Public Library of Science, vol. 13(12), pages 1-21, December.
    12. Kang, Fangyuan & Sun, Liuquan & Zhao, Xingqiu, 2015. "A class of transformed hazards models for recurrent gap times," Computational Statistics & Data Analysis, Elsevier, vol. 83(C), pages 151-167.
    13. Hao, Meiling & Zhao, Xingqiu & Xu, Wei, 2020. "Competing risk modeling and testing for X-chromosome genetic association," Computational Statistics & Data Analysis, Elsevier, vol. 151(C).
    14. Bunea, Florentina & McKeague, Ian W., 2005. "Covariate selection for semiparametric hazard function regression models," Journal of Multivariate Analysis, Elsevier, vol. 92(1), pages 186-204, January.
    15. Zahra Mansourvar & Torben Martinussen, 2017. "Estimation of average causal effect using the restricted mean residual lifetime as effect measure," Lifetime Data Analysis: An International Journal Devoted to Statistical Methods and Applications for Time-to-Event Data, Springer, vol. 23(3), pages 426-438, July.
    16. Möst Lisa & Hothorn Torsten, 2015. "Conditional Transformation Models for Survivor Function Estimation," The International Journal of Biostatistics, De Gruyter, vol. 11(1), pages 23-50, May.
    17. Bhattacharjee, Arnab, 2004. "Estimation in hazard regression models under ordered departures from proportionality," Computational Statistics & Data Analysis, Elsevier, vol. 47(3), pages 517-536, October.
    18. Thomas H. Scheike & Mei-Jie Zhang, 2003. "Extensions and Applications of the Cox-Aalen Survival Model," Biometrics, The International Biometric Society, vol. 59(4), pages 1036-1045, December.
    19. Qu, Lianqiang & Song, Xinyuan & Sun, Liuquan, 2018. "Identification of local sparsity and variable selection for varying coefficient additive hazards models," Computational Statistics & Data Analysis, Elsevier, vol. 125(C), pages 119-135.
    20. Peng He & Frank Eriksson & Thomas H. Scheike & Mei-Jie Zhang, 2016. "A Proportional Hazards Regression Model for the Subdistribution with Covariates-adjusted Censoring Weight for Competing Risks Data," Scandinavian Journal of Statistics, Danish Society for Theoretical Statistics;Finnish Statistical Society;Norwegian Statistical Association;Swedish Statistical Association, vol. 43(1), pages 103-122, March.

    Corrections

    All material on this site has been provided by the respective publishers and authors. You can help correct errors and omissions. When requesting a correction, please mention this item's handle: RePEc:sae:somere:v:39:y:2010:i:2:p:157-187. See general information about how to correct material in RePEc.

    If you have authored this item and are not yet registered with RePEc, we encourage you to do it here. This allows to link your profile to this item. It also allows you to accept potential citations to this item that we are uncertain about.

    If CitEc recognized a bibliographic reference but did not link an item in RePEc to it, you can help with this form .

    If you know of missing items citing this one, you can help us creating those links by adding the relevant references in the same way as above, for each refering item. If you are a registered author of this item, you may also want to check the "citations" tab in your RePEc Author Service profile, as there may be some citations waiting for confirmation.

    For technical questions regarding this item, or to correct its authors, title, abstract, bibliographic or download information, contact: SAGE Publications (email available below). General contact details of provider: .

    Please note that corrections may take a couple of weeks to filter through the various RePEc services.

    IDEAS is a RePEc service. RePEc uses bibliographic data supplied by the respective publishers.