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Assessing real-world effectiveness of therapies: what is the impact of incretin-based treatments on hospital use for patients with type 2 diabetes?

Author

Listed:
  • Clémence Bussiere

    (University of Paris Est Créteil
    MGEN Foundation for Public Health)

  • Pauline Chauvin

    (Université Paris Cité
    Centre des Saints-Pères)

  • Jean-Michel Josselin

    (CREM (CNRS-UMR6211), University of Rennes 1)

  • Christine Sevilla-Dedieu

    (Université Paris Cité)

Abstract

Background Managing type 2 diabetes represents a major public health concern due to its important and increasing prevalence. Our study investigates the impact of taking incretin-based medication on the risk of being hospitalized and the length of hospital stay for individuals with type 2 diabetes. Method We use claim panel data from 2011 to 2015 and provide difference-in-differences (DID) estimations combined with matching techniques to better ensure the treatment and control groups’ comparability. Our propensity score selects individuals according to their probability of taking an incretin-based treatment in 2013 (N = 2,116). The treatment group includes individuals benefiting from incretin-based treatments from 2013 to 2015 and is compared to individuals not benefiting from such a treatment but having a similar probability of taking it. Results After controlling for health-related and socio-economic variables, we show that benefiting from an incretin-based treatment does not significantly impact the probability of being hospitalized but does significantly decrease the annual number of days spent in the hospital by a factor rate of 0.621 compared with the length of hospital stays for patients not benefiting from such a treatment. Conclusion These findings highlight the potential implications for our health care system in case of widespread use of these drugs among patients with severe diabetes.

Suggested Citation

  • Clémence Bussiere & Pauline Chauvin & Jean-Michel Josselin & Christine Sevilla-Dedieu, 2022. "Assessing real-world effectiveness of therapies: what is the impact of incretin-based treatments on hospital use for patients with type 2 diabetes?," Health Economics Review, Springer, vol. 12(1), pages 1-9, December.
    • Handle: RePEc:spr:hecrev:v:12:y:2022:i:1:d:10.1186_s13561-022-00397-5
    DOI: 10.1186/s13561-022-00397-5
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    References listed on IDEAS

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    1. Ai, Chunrong & Norton, Edward C., 2003. "Interaction terms in logit and probit models," Economics Letters, Elsevier, vol. 80(1), pages 123-129, July.
    2. Jeffrey M Wooldridge, 2010. "Econometric Analysis of Cross Section and Panel Data," MIT Press Books, The MIT Press, edition 2, volume 1, number 0262232588, April.
    3. Clémence Bussière & Nicolas Sirven & Thomas Rapp & Christine Sevilla‐Dedieu, 2020. "Adherence to medical follow‐up recommendations reduces hospital admissions: Evidence from diabetic patients in France," Health Economics, John Wiley & Sons, Ltd., vol. 29(4), pages 508-522, April.
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