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Comparison of the three-level and the five-level versions of the EQ-5D

Author

Listed:
  • Anne Simone Juhl Christiansen

    (University of Southern Denmark)

  • Marie Louise Sletskov Møller

    (University of Southern Denmark)

  • Christian Kronborg

    (University of Southern Denmark)

  • Ketil Jørgen Haugan

    (Zealand University Hospital Roskilde)

  • Lars Køber

    (Copenhagen University Hospital
    University of Copenhagen)

  • Søren Højberg

    (Bispebjerg Hospital, Copenhagen University Hospital)

  • Axel Brandes

    (Odense University Hospital
    University of Southern Denmark)

  • Claus Graff

    (Aalborg University)

  • Søren Zöga Diederichsen

    (Copenhagen University Hospital)

  • Jonas Bille Nielsen

    (Copenhagen University Hospital
    Statens Serum Institut
    Norwegian University of Science and Technology)

  • Derk Krieger

    (University Hospital Zurich, University of Zurich
    Stroke Unit, Mediclinic City Hospital)

  • Anders Gaarsdal Holst

    (Copenhagen University Hospital)

  • Jesper Hastrup Svendsen

    (Copenhagen University Hospital
    University of Copenhagen
    Copenhagen University Hospital)

Abstract

EQ-5D is a generic instrument to measure health-related quality of life. In 2009, a new version, EQ-5D-5L, was introduced as an attempt to reduce ceiling effects and improve sensitivity to small changes over time. The objective of this study was to assess the measurement properties of the EQ-5D-5L instrument compared to the EQ-5D-3L instrument in an elderly general population with a moderate to a high degree of comorbidity. A subgroup of participants in a large clinical trial completed the EQ-5D-3L and the EQ-5D-5L questionnaires. Based on the collected data, we tested for feasibility and ceiling and floor effects. Furthermore, we assessed the redistribution properties of the responses and examined the level of inconsistency, informativity, and convergent validity. A total of 1002 persons diagnosed with hypertension, diabetes, heart failure, and/or previous stroke completed both the EQ-5D-3L and the EQ-5D-5L questionnaires. The overall ceiling effect decreased from 46% with the EQ-5D-3L to 30% with the EQ-5D-5L and absolute and relative informativity were higher for EQ-5D-5L, and there was a stronger correlation between EQ-5D-5L and EQ VAS. The EQ-5D-5L seemed to perform better than the EQ-5D-3L in terms of feasibility, ceiling effect, discriminatory power, and convergent validity. The overall ceiling effect was higher than that found in patient samples in previous studies but lower than the one found in population studies.

Suggested Citation

  • Anne Simone Juhl Christiansen & Marie Louise Sletskov Møller & Christian Kronborg & Ketil Jørgen Haugan & Lars Køber & Søren Højberg & Axel Brandes & Claus Graff & Søren Zöga Diederichsen & Jonas Bill, 2021. "Comparison of the three-level and the five-level versions of the EQ-5D," The European Journal of Health Economics, Springer;Deutsche Gesellschaft für Gesundheitsökonomie (DGGÖ), vol. 22(4), pages 621-628, June.
    • Handle: RePEc:spr:eujhec:v:22:y:2021:i:4:d:10.1007_s10198-021-01279-z
    DOI: 10.1007/s10198-021-01279-z
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    References listed on IDEAS

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    1. Ines Buchholz & Mathieu F. Janssen & Thomas Kohlmann & You-Shan Feng, 2018. "A Systematic Review of Studies Comparing the Measurement Properties of the Three-Level and Five-Level Versions of the EQ-5D," PharmacoEconomics, Springer, vol. 36(6), pages 645-661, June.
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    More about this item

    Keywords

    EQ-5D-5L; EQ-5D-3L; Health-related quality of life; Measurement properties;
    All these keywords.

    JEL classification:

    • I10 - Health, Education, and Welfare - - Health - - - General

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