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The effect of childhood trauma on age of onset in patients with schizophrenia

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  • Cem Ä°ngeç
  • Esin Evren Kılıçaslan

Abstract

Purpose: Childhood trauma (CT) has been shown to affect the etiology and clinical features of schizophrenia. In this study, it was aimed to investigate the effects of CT on the age of onset (AoO) and clinical features of the disease by considering factors such as family history, head trauma, birth trauma, alcohol and substance abuse that may affect AoO of the disease. Methods: The sample comprising 200 patients admitted to the outpatient and inpatient care at the Izmir Katip Çelebi University, Atatürk Education and Research Hospital psychiatry clinic, were included in the study. Socio-demographic information form, Positive and Negative Syndrome Scale (PANSS), Childhood Trauma Questionnaire-Short Form (CTQ-SF) and subscale of Mini-International Neuropsychiatric Interview (MINI) were applied. Results: All types of trauma, except physical abuse, were found related to the disease onset age earlier. It was also detected that the factors of head trauma, birth complication, presence of an individual diagnosed with schizophrenia in the family and migration history were not related to AoO of the disease. On the other hand, it was found that physical, emotional and sexual abuses lead to more positive psychotic symptoms, and all types of CT increase the severity of disease and the risk of suicide. Conclusion: This study draws attention to the etiological importance of CT in schizophrenia as an environmental factor by showing that it affects AoO of the disease along with symptomatology. Future studies should focus on the pathogenesis of CT in schizophrenia and the interaction between CT and biological and genetic predisposition.

Suggested Citation

  • Cem Ä°ngeç & Esin Evren Kılıçaslan, 2020. "The effect of childhood trauma on age of onset in patients with schizophrenia," International Journal of Social Psychiatry, , vol. 66(8), pages 763-769, December.
    • Handle: RePEc:sae:socpsy:v:66:y:2020:i:8:p:763-769
    DOI: 10.1177/0020764020943629
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    1. Rosana E Norman & Munkhtsetseg Byambaa & Rumna De & Alexander Butchart & James Scott & Theo Vos, 2012. "The Long-Term Health Consequences of Child Physical Abuse, Emotional Abuse, and Neglect: A Systematic Review and Meta-Analysis," PLOS Medicine, Public Library of Science, vol. 9(11), pages 1-31, November.
    2. G. Baudin & O. Godin & M. Lajnef & Bruno Aouizerate & F. Berna & L. Brunel & D. Capdevielle & I. Chereau & J. M. Dorey & C. Dubertret & J. Dubreucq & C. Faget & G. Fond & F. Gabayet & H. Laouamri & C., 2016. "Differential effects of childhood trauma and cannabis use disorders in ă patients suffering from schizophrenia," Post-Print hal-01482654, HAL.
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